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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

TTC Super Ovulation part 2

999 replies

suemays · 17/05/2012 17:45

hey ladies,

There are a few of us who are ttc after mc's, however there will be ladies out there who are also ttc for the first time or second or third without success. If anyone is on, considering or had success on a super ovulation programme then do join us. How long did it take ? Did you try IUI with it.. ? Did you have PCOS?

Kicking this off and hoping some of you will join....

part 1 here:
www.mumsnet.com/Talk/conception/1385998-TTC-Super-Ovulation

OP posts:
Arianrhod · 04/10/2012 22:51

Thanks rainbows but the LAD results really are a show stopper. Without paternal antibodies my body will kill off any embryo every single time. I think this might just be our end of road.

Mel3062 · 05/10/2012 06:06

Ari im so sorry about your results I've everything crossed for you except legs as its my scan today ;) xx its not fair the struggle we all have

Pebbles73 · 05/10/2012 07:24

Oh st Ari am so sorry, what a total nightmare and as Rainbows said I desperately hope this one works out for you, you so deserve it.x

Good luck for today Mel.

lemonsherbet · 05/10/2012 08:47

ari I am sorry, is it worth seeing Dr G to see if there is anything that he can suggest. I think he routinely does these tests. Would you be able to do IVF with them selecting the 50% that are not identical to you? I have no idea just guessing here. The other thing is you still have a BFP so your little one is hanging in there. So this one may still work out for you

Chasinrainbows · 05/10/2012 08:50

Mollie I'm 4+5 so still very early days.

Good luck with yor scan today mel

jaffajiffy · 05/10/2012 08:58

ari just lurked on the pred thread and don't really know about these tests but it sounds like bad news after bad news for you, which is so hard. I suppose you're just waiting for your body to reject whatever's going on in there? Seems so hopeless even though you have a BFP! I'm very, very sorry. What does Mr S say about the results? it's so hard. I will say a little prayer for you.

mel good luck today.

duggs1976 · 05/10/2012 08:59

ari sent message on pred thread about seeing dr gorgy. As heroic as dr s has been for some folk - he is limited. PM me if you'd like more details x

duggs1976 · 05/10/2012 09:00

Agree with lemon!!

jaffajiffy · 05/10/2012 09:00

PS and like the others I'm going to hope against hope that the little bean defies the odds.

Arianrhod · 05/10/2012 09:34

Thanks ladies, but this one is already over for us, BFN this morning. Posted in full on the pred thread but even with LIT treatment there's very little chance it will work for us, because of our 100% DQa match. I just don't see any further avenues for us, even with Dr G, as I don't think I'm prepared to go through donor LIT (white blood cells get injected into you from someone other than your OH), neither the huge cost nor the still-low chance of it working. Even if we could afford IVF - which we can't - it would have to be donor sperm, as it seems I am just too genetically close to OH, and that I won't do.

mel good luck for your second follie scan today, I hope they've improved!!

Mel3062 · 05/10/2012 09:42

Aww thanks ladies xx hugs Ari

jaffajiffy · 05/10/2012 10:11

ari I'm so sorry. Sending every good wish your way as you process this loss and the results x x

Chasinrainbows · 05/10/2012 10:12

So sorry Ari :( Xxx

Arianrhod · 05/10/2012 10:36

Thanks ladies.

Oh, and kittens, I meant to say last night but was too busy trying to see wood for trees ... yes, I found the intralipid experience a bit odd on Monday too. I don't know if they were really busy, or what, but I sat there for 20 mins with an empty intralipid bag wondering if they were coming back, and in the end I went out to reception with my drip in tow to see! They did check my blood pressure twice, once before and once during, and the nurse did come in once to check but then left me to it, which was very different to the last time I had ILs done. Did they do yours in your hand?? I only ask because they did that to me the first time and had a right old time trying to get it in (and it HURT like hell); this time, they remembered, and did it in my arm, and it went in as easy as pie. If they did yours in your hand, ask them to do it in your arm next time!!

Mel3062 · 05/10/2012 10:54

Got 4 on each ovary today!! All quite small though measuring 7,4,5,3,9,5,6,8 so ill see what mr s says, I had one at 10 on mon so why has it gone to 9?!

Havingkittens · 05/10/2012 11:06

They did it in my arm in the end. They tried all over the place on each arm and hand. I do have tiny and invisible veins though and apparently each one they tried branched off so they couldn't get the cannula all the way in. I was extremely tired and a bit dehydrated I think. They ended up getting me to drink more water and rest for a while before they came back and managed to do it on the second try after that. I don't think that bit was their fault but it was slightly traumatic.

I posted on the pred thread just now but Ari, I'm so sorry for the rollercoaster you've been through this past few weeks with your latest chemical and now your devastating results. You've got a lot to process. Sending you a big fat hug. xx

BellyD · 05/10/2012 11:50

Hi Ari just wanted to say I am so sorry about your chemical and your test results. Must be a huge amount to take on board. I wish things were so different for you.

For what it's worth after taking advice from Dr Duggs we went to see Dr G in our enforced ttc break and I tested -ve to LAD as well. Mr S totally dismissed this result as irrelevant (although he was pretty unimpressed we had been to Dr G mind you) and an allergy/immunology specialist I also went to see rubbished it too (although his field isn't rmc as such). I was gutted with my result too - our levels were really low, would need a vat of white blood cells to get anywhere near 100%. So I am burying my head in the sand about it and hoping Dr S and the other guy are right, although a part of me does feel it makes sense. I, like you, read negative and thought that was good news - wrong.

My tnf aplha is also high which requires humira. Not sure if anyone apart from Choccy has taken that? Again side effects hideous, especially if you are hyper allergic to things like I am. Half of me thinks we should throw everything at it as it will prob be our last try and the other half of me is terrified of how I will react to the drugs both in the short term and long term. We have decided to try once more naturally until Jan. This time taking the steroids from bfp and see what happens. Been for a follie scan today and have 5 ripe ones, one too large but others all good and lining ok. Mr S said it was the response of a 20yr old!

Really thinking of you Ari.

Arianrhod · 05/10/2012 12:01

belly Thanks, and thanks for posting about your testing, I'm really interested in what you're saying. Mr S rubbished it? Really? How on earth can he do that, when all other consultants everywhere say it's so very relevant - and it makes total sense, too? I'm stunned, to be honest - if your body cannot distinguish between your OH's DNA and your own enough to know that an embryo is 'foreign but ok' and so to be protected, then it makes perfect sense that your body would kill it off, surely? Scientific sense, too.

I haven't heard from Mr S and obviously won't until I go in to see him on the 17th (there isn't a non-scan appt free until then anyway, so Cheryl said to keep my original scan appt) but it sounds belly like you and I are in a very similar position with regards to LAD - I too would need a vat of white blood cells to get anywhere near a positive result.

On the TNF-alpha front - do you know there are some supplements that might help this too? I PMd some info to choccy, don't know if it was of any help but PM me belly if you're interested?

I don't know what to think now - I'm still stunned that Mr S can be so dismissive of this. How?

Arianrhod · 05/10/2012 12:02

And kittens thanks so much, appreciate any and all hugs right now :)

Arianrhod · 05/10/2012 12:05

belly Sorry, I meant to ask, could I ask what your LAD results were? PM me if you would rather. I'm still stunned at Mr S's response ...

Arianrhod · 05/10/2012 13:02

belly .. just a bit of a follow-up ... been reading around the other fertility boards (trying to get my head around why Mr S doesn't 'believe' in low LAD being a problem) and found this post, from a lady April last year:

I was LAD negative when tested prior to this IVF tx as well as having an aggressive DQ match with DH and a v. strong NK response. So you'd think a prime candidate for LIT?

However, CARE only prescribed Intralipids and steroids for this - as this is what was deemd to work. i.e. it was enough to lower my body's NK response. LIT was never mentioned. It has thankfully seemed to work...

She had a baby, after four miscarriages not on immune treatment, with just intralipids and steroids.

Go figure!

LJ71 · 05/10/2012 14:13

Ari sending you even more hugs. Thinking of you xx

BellyD · 05/10/2012 14:20

Ari will dig out my results and post them later this eve for you, I think some of the percentages were single digit! Mr G said prior to the test that he thought I would test positive for it as I have been Preg 5 times I was bound to have developed antibodies to DH - obv not! Mr S was in a huff and said he wouldn't interpret anyone else's results, he barely glanced at the LAD test before dismissing it but he couldn't help himself look at the tnf alpha test which he was interested in. Would be very interested to hear about the supplements if you wouldn't mind pm'ing me. That quote is fascinating. Don't know what to make of it all. X

Arianrhod · 05/10/2012 14:26

Ha! Well considering Mr S himself ordered my tests, he'll jolly well have to look at my results - but if he doesn't believe in LIT, as I'm increasingly reading more and more don't, I don't know quite what difference it makes. I have just been having a trawl through the support forum for the CARE Fertility centre (IVF) and it seems their 'main man' Dr George no longer prescribes LIT for low LAD, even when DQa matches are involved - he just ups the frequency of intralipids. I really don't know what to make of it all. Will PM you.

Arianrhod · 05/10/2012 14:27

And thank you LJ :)