TTC/Pregnancy on Prednisolone or similar part 6

[Arianrhod]

A positive thread for all those diagnosed with High or Very High NK Cells and looking to start TTC or already pregnant on Prednisolone and/or Intralipid treatment.

Newcomers very much welcome!

Part 5 www.mumsnet.com/Talk/conception/1391787-TTC-Pregnancy-on-Prednisolone-or-similar-part-5

Part 4 www.mumsnet.com/Talk/conception/1366323-TTC-Pregnancy-on-Prednisolone-or-similar-part-4

Part 3 www.mumsnet.com/Talk/conception/1348773-TTC-pregnancy-on-Prednisolone-or-similar-part-3

Part 2 here www.mumsnet.com/Talk/conception/1323594-TTC-pregnancy-on-Prednisolone-or-similar-part-2

Part 1 here www.mumsnet.com/Talk/conception/1236324-TTC-pregnancy-on-Prednisolone-or-similar

Morning ladies!

choccy that's (cautiously) fantastic news! Your first cycle of TTC and a (cautious) BFP!! Woohoo, I'm so very (cautiously) pleased for you!! :)

lemon I take Folapro l-methylfolate supplements - they're not cheap, unfortunately, but since I'm homozygous it makes absolutely no sense taking folic acid. I also sympathise with the feeling like you'll never get a BFP again, this is my third cycle since TTC after the last early MC and I've always managed to be pg by second cycle until now. Mr S also gave me enough meds for 8 cycles when I saw him in Jan and said "see you when you're pregnant", leaving me thinking 8 cycles? If I'm not pg before then I'll be panicking! If you feel you should see him again, then do - it's your peace of mind after all.

olives I think everyone's different with their reaction to the pred (2:20am the sleep problems started for me this morning :( ) but for me I think by the second day of stopping taking it I'm mostly back to normal sleeping, it comes out of my system pretty quickly. Like you though although I should be resembling the walking dead today with so little sleep, my energy levels are actually ok. What the pred takes away with one hand, verily it giveth back with the other :)

Well 5dpo here and feeling decidedly meh about the whole thing again. No signs of anything, but I know it's really too early to have any symptoms since any fertilised egg wouldn't have implanted yet. Thinking I should be feeling implantation pangs in a couple of days time IF it's going to happen this month, but not holding my breath. Due to see my acupuncturist on Wed, 7dpo, and hoping she doesn't tell me she thinks I'm pregnant like she did once before (when I wasn't!).

/waves to everyone, and another (cautious) woohoo for choccy :)

Whispering well done choccy!! First step ticked off the list as it were

olive just a bit knackered after stopping the pred for me but yes most hideous sleep on it, worse than having a new born! Asked louise about it and she basically said have to put up with it as the pred is the most effective immume suppresant. But i will talk with Dr S tomorrow when I have my follicle scan.

choccy whispered yay from me too!! In the spirit of positivity I'll do the honours with the list update...

Monday 19th March

The babies are arriving!
Stogan - V high NKC - cycle#2, DC#1, Baby girl born Sunday 11/03/12 7lb13.5. Our First Pred Thread Baby!

BFP
3rd Trimester
Digitalgirl - High NKC - BFP cycle#2, DC#2 36+0 Due 16/04/12 Consultant appt 13/3/12
Coconutfeet - V High NKC, Factor II gene mutation, underactive thyroid - BFP pre-pred, started at 6 weeks 33+0
Comedy - V High NKC - BFP cycle#2, DC#2 ? 30+3 C-section booked: 14/5/12
Iggi - High NKC & Hypothyroidism - BFP cycle#2, DC#2- 29+6 c-section booked for 21/5/12
BrownieGecko - High NKC, Hypothyroidism, & Glucose Intolerant. BFP Clomid cycle#3, DC#1 29+3

2nd Trimester
Freelance - V High NKC TTC#1 Hydroxychloroquine, Pred, Intralipids, 400 Cyclogest, Thyroid/hashimotos. MC 1st Pred cycle. DC#1 21+6 Next scan TBC.
Cheerfulcharlie - V High NKC, MTHFR, DC#2/ (metformin, intralipids, no pred). 21+5
batteryhen - High NKC, factor v leiden. DC#1 BFP cycle 3. 18+4 Amnio 14/3/12.
coleyoz - V High NKC. DC#2, BFP cycle2, 18+1

1st Trimester
FrozenNorthPole - RMC, NKC status unknown, Cyclogest, aspirin, 13+2, NT scan 12/03
Mercator - V High NKC, TTC#2. 13+3, Next scan 14/3
Hopefulfor2nd - High NKC - TTC#2. - 12+4 12 week scan this week.
dunnit - V High NKC - TTC#1, on Pred, IVIG, prog and Clexane. 12+4 Nuchal/12wk Scan 16th March
PQ77 - V High NKC TTC #2 (BFP cycle one but mc) 8+0
ChoccyPud - V High NKC - TTC#1 from March (Pred & Hydroxychloroquine) 3+4

TTC
Waiting to test
Pebbles - TTC#1 High NKC, PCOS, super ov cycle 1 (post IVF - 1 chemical, 1 mc)
Arianrhod - V High NKC, MTHFR homo, hypothyroid, TTC#2 (Pred & Hydroxychloroquine)

Waiting to ovulate
Cherrycheeks - V high NKC, TTC#2
Havingkittens - Upgraded from High to V High NKC TTC #1 1st cycle Super Ov
buster76 -V High NKC, Factor V Leiden.
Lemonsherbet - TTC#1 v high/high NK, Mthfr, thyroid issues, pred 1st trim & Intralipids 2nd on bfp
BellyD - V High NKC, MTHFR homo, TTC#1 cycle 2
eurochick - TTC#1 High NKC, pred cycle 4,
Snoopygirl - V High NKC TTC, pred cycle 5, Super Ov Cycle 2
Willitbe - RMC, NKC not tested, TTC #4 cycle 2 (after m/c 12) Fertility consultant prescribed pred.
duggs1976 - High/V High NKC - TTC #1 - IVF cycle

WTTC
ScooterChaser - V High NKC - TTC#2 (Pred & Hydroxychloroquine)
Breezyweezy - V High NKC - TTC#1
AandRmum - High NKC
Cornflakes30 - V High NKC, underactive thyroid
picolina - V High NKC MC on treatment
Brownstag - V High NKC, 3 yo DS is a Pred Baby! TTC #2
Zoeella V.high NKC, Factor V Leiden. abandoned IVF, pos PCOS
Suemays - V High NKC, TTC #2. Superov. (Pred & Hydroxychloroquine)
Holldoll - High NKC - Pred, Cyclogest & aspirin

choccy Whispered congrats to you :) RE your dads drip, do you mean TPN? It's total parental nutrition. It goes straight into he vein, and contains all the nutrients he needs, and is very high in calories. It's not the same as intra lipids, as it contains many more nutrients xx
olives I wasn't too bad on the pred, I did wake up early but being a sleep monster- I just went straight back to sleep.
duggs You are doing so well on all your treatment - Your time must be now surely. I will keep my fingers crossed for you xx
ari - I won't say anything but 5dpo?? Really??!! You could very well be pregnant lady and not know it yet - I will keep my fingers crossed for you too xx :)
kittens I hope you are ok too, your time is coming soon I am sure xx

Big wave to everyone else xxxx

Great first steps choccy! X x

just a quick question, ive been nearly 2 weeks off pred and noticed my joints , knee and hip really stiff and painful, esp when ive been sitting and get up to walk, its a bit better after moving around but still sore, anyone else have this?

choccy everything crossed ofr you!

Oh my goodness Choccy! Well done!! And yes we are all cautiously optimistic with you but here is the place to be cautiously optimistic as we all know how that feels. Great that you are pumping yourself with the pharmaceuticals too! We all have our fingers crossed for you I am sure.

Ari, as you know 5 DPO is still very very early! But that 2ww is a bitch I know.

Pico I definitely still had joint aches for a while after the Pred. It takes quite a while to fully get out of the system I think.

Frozen so glad you have sorted out the risk factor. It is so stressful waiting for results etc.

Digi well done for doing the list too - and for changing Choccy in the spirit of positivity! Hope you're not feeling too physically immobile.

Great Pred article Willitbe! It's actually one I haven;t found before. I thought I had found everything there was to know about it, in my pre-Pred and Pred taking days so it's great to add more research to the thread! Hope it is informative for Lemon and others with AF woes.

Coconut am feeling your pain with the house hunting! We;ve seen 20 places or more so far and nothing to show for it. I am away this week and also away again the end of the following week so am hoping that after this natural break in searching there might be more stuff on the market.

In regards pregnancy etc I am finding it helpful that I have started to feel movements. Sometimes I can even see my stomach jumping when I get an especially big kick! There seemed to be a bit of a lull in kicks yesterday so I had to get the doppler out, but generally it is quite lively in the evenings.

I look pregnant now too - people have started to offer me seats on public transport. Only women so far though! So I've always felt bad and said no. I can feel my stomach expanding some days and today weighed myself and have hit 70kg which I think is roughly 11 stone. Ouch! Mind you, when I first got ill with the thyroid illness and put on over three stone in about three months I did hit almost 12 stone, so I have been heavier than this.

This is a pretty crap post from me as I have been at a geeky travel technology conference all day and still have to finalise an article for the US market, so still working. Sorry if I have missed anything vital xx

Thanks girls

battery you're right I did mean TPN, sorry, thanks for the info.

They managed to squeeze me into NLC this morning so I've had intralipids nice and quickly too. I am SO lucky living close by, though it was a bit of a mad rush down there first thing!

It's all a waiting game at this stage anyway, as we all know only too well. I'll be happy getting as far as a not-definitely-bad 6 week scan.

ari fingers crossed those pangs hit in a few days...

Hey ladies quick hello from me !

Not long now digi eeekkkk so exciting can't wait to hear ur amazing news
Fab news choccyeverything crossed for you x
Hi greenolives sure I remember you ? Thanks for the good wishes and best of luck on ur journey, your in great hands on here !

Great news on the amino battery

dunniT such a lovely post from u and fantastic news
duggs huge good luck wishes for the IVF X
willitbe thanks for the mothers day wishes was a fantastic, surreal and emotional day and my little bundle spoiled me rotten and daddy even got me an eternity ring !

Well I'm sat here with a very wriggly 9 day old baby on my knee eating her fists so I'd better go prepare my breasts (I'm surprised people can see them from space they're huge !!!)

Massive love and hugs to everyone else xxx

Choccy That's brilliant news and great that you got the intralipids so quickly. Fingers crossed!

Ari 2.20 is just not funny I was feeling all positive yesterday as I didn't wake until 5am and then I managed to get back to sleep until I got up for work at 6.20. However after a VERY long and tiring 13 hour shift yesterday I have been awake since 3.30 today- bleurrgh! I am 10dpo today and doing my usual symptom spotting, not testing until Friday though. Hope you have some positive signs over the next few days!

Stogan So glad you were thoroughly spoiled on Mothers day, enjoy those lovely newborn snuggles

Tuesday 20th March
The babies are arriving!
Stogan - V high NKC - cycle#2, DC#1, Baby girl born Sunday 11/03/12 7lb13.5. Our First Pred Thread Baby!

BFP
3rd Trimester
Digitalgirl - High NKC - BFP cycle#2, DC#2 36+1 Due 16/04/12 Consultant appt 13/3/12
Coconutfeet - V High NKC, Factor II gene mutation, underactive thyroid - BFP pre-pred, started at 6 weeks 33+1
Comedy - V High NKC - BFP cycle#2, DC#2 ? 30+4 C-section booked: 14/5/12
Iggi - High NKC & Hypothyroidism - BFP cycle#2, DC#2- 30+0 c-section booked for 21/5/12
BrownieGecko - High NKC, Hypothyroidism, & Glucose Intolerant. BFP Clomid cycle#3, DC#1 29+4

2nd Trimester
Freelance - V High NKC TTC#1 Hydroxychloroquine, Pred, Intralipids, 400 Cyclogest, Thyroid/hashimotos. MC 1st Pred cycle. DC#1 22+0 Next scan TBC.
Cheerfulcharlie - V High NKC, MTHFR, DC#2/ (metformin, intralipids, no pred). 21+6
batteryhen - High NKC, factor v leiden. DC#1 BFP cycle 3. 18+5 Amnio 14/3/12.
coleyoz - V High NKC. DC#2, BFP cycle2, 18+2

1st Trimester
FrozenNorthPole - RMC, NKC status unknown, Cyclogest, aspirin, 13+3, NT scan 12/03
Mercator - V High NKC, TTC#2. 13+4, Next scan 14/3
Hopefulfor2nd - High NKC - TTC#2. - 12+5 12 week scan this week.
dunnit - V High NKC - TTC#1, on Pred, IVIG, prog and Clexane. 12+5 Nuchal/12wk Scan 16th March
PQ77 - V High NKC TTC #2 (BFP cycle one but mc) 8+1
ChoccyPud - V High NKC - TTC#1 from March (Pred & Hydroxychloroquine) 3+5

TTC
Waiting to test
Pebbles - TTC#1 High NKC, PCOS, super ov cycle 1 (post IVF - 1 chemical, 1 mc)
Arianrhod - V High NKC, MTHFR homo, hypothyroid, TTC#2 (Pred & Hydroxychloroquine)
GreenOlives - High NKC, TTC#2 First Pred cycle

Waiting to ovulate
Cherrycheeks - V high NKC, TTC#2
Havingkittens - Upgraded from High to V High NKC TTC #1 1st cycle Super Ov
buster76 -V High NKC, Factor V Leiden.
Lemonsherbet - TTC#1 v high/high NK, Mthfr, thyroid issues, pred 1st trim & Intralipids 2nd on bfp
BellyD - V High NKC, MTHFR homo, TTC#1 cycle 2
eurochick - TTC#1 High NKC, pred cycle 4,
Snoopygirl - V High NKC TTC, pred cycle 5, Super Ov Cycle 2
Willitbe - RMC, NKC not tested, TTC #4 cycle 2 (after m/c 12) Fertility consultant prescribed pred.
duggs1976 - High/V High NKC - TTC #1 - IVF cycle

WTTC
ScooterChaser - V High NKC - TTC#2 (Pred & Hydroxychloroquine)
Breezyweezy - V High NKC - TTC#1
AandRmum - High NKC
Cornflakes30 - V High NKC, underactive thyroid
picolina - V High NKC MC on treatment
Brownstag - V High NKC, 3 yo DS is a Pred Baby! TTC #2
Zoeella V.high NKC, Factor V Leiden. abandoned IVF, pos PCOS
Suemays - V High NKC, TTC #2. Superov. (Pred & Hydroxychloroquine)
Holldoll - High NKC - Pred, Cyclogest & aspirin

Have added myself to the list, hope I've not cocked it up! x

Aww Stogan that's lovely! How are you getting on? Is she gorgeous? Have you had any sleep..?! Can't believe you are sitting there with your little girl at last. Lovely present with the eternity ring too! Is it a clear diamond one? Bet it's gorgeous.

Olives thanks for doing the list! All looks good to me. Yes sleeping on the Pred can be a real pain. I seemed to find it worse for the first week or so but then adjust to it slowly. Didn't notice any serious difference in sleep when upping it to 40mg but then at that point I was pregnant (twice) and of course that comes with other sleep issues.

It is great to have Choccy on the BFP list. We had a bit of a gap in new BFPs after the chemicals. Same thing happened just before me, as there is a big gap between myself and the next person above me (Brownie by the way, I do hope she's ok).

So, I am 22 weeks today and looking forward hopefully to another 2 weeks when I could reach viability. I know things go wrong still but I feel that would be a good milestone. And Charlie is at the same stage as me too.

just a quick one from me to say yay for choccy - really kicking myself as I was at NL yesterday getting intralipids too at I think I must have overlapped with you a bit - I got there just before midday. Was going to text you and scooter seeing as you are both in the vicinity but ran out of time and had massive childcare problems so couldn't hang about (as it was a lovely friend got lumbered with DS for nearly 6 hours all told).

At any rate I slept through the whole IV - am feeling at bit sorry for myself at the moment. Horrible nausea just eating non stop to try and keep it at bay (and I weigh more than free already!) and obviously I would just suck it up and take it as a great sign were it not for the fact that I keep on mentalling that there's something horribly wrong. Next scan on Thursday - will be 8.5 or so, so that should be a good next step (Mr S reckons 9 weeks is the really critical date I think you mentioned once digi?). Sorry for the moan, am just really struggling a bit this week .

Lovely to hear from you stogan

Hello PQ yes 9 weeks is a huge milestone according to Mr S. He told me he sees it as more significant than 12 weeks. So it would indeed be a great sign if all is ok on Thursday.

How lovely that you slept through the intralipids. I know for people with small children it can be quite a relaxing affair!

I know I am probably not the most childcare-savvy person you know but if you are ever really, really stuck do ask me as I might be free and able to at least go hang out at yours for a few hours and make sure DS stays safe and is fed! Whether he would cry all the way through or not is another issue :) but am sure we could happily watch cartoons or something together.

And I know from seeing you a couple of weeks ago that you are still very much a slim thing, so don't worry about that at all!

I was just about to suggest coffee but remembered am off up north tomorrow.

Damn - I really have so much work to do but have got caught up with Dr Google again.

Thanks free, very kind of you indeed. DS would be delighted to hang out with you I'm sure! Just had some more brown spotting so in a dark cave of gloominess. I know I could rush into the EPAU but I think I'll hang on until my appt on Thursday

Quick, someone share some good news!

PQ Oh Hun not more that's crap. It could still be that patch of bleeding you saw before? I'm sorry you're having to worry about more of this. Big hugs and everything crossed xx

And a kind of joke to share. You know how IT people will refer to "picnic" when dealing with stupid queries? Problem In Chair Not In Computer.

Well, DH just responded to me being dopey and missing a very easy point with PIWNIB. Problem In Womb Not In Brain! Charming

Oh heck PQ you didn't need that, but as choccy says hopefully it's just the last remnants from that patch of bleeding you had before. Hang in there girl, we're all rooting for you!

choccy how you doing this morning? Err no, it's afternoon now, well you know what I mean! Are you being a terribly good person (unlike me) and laying off the repeat testing??

Olives I'm so with you on the knackered-ness stakes. Started at 1:50am this morning, dozed and woke and dozed and woke all the way until my alarm went off at 6:15am. Ah well, it's all good practice for those early baby days, right? ;) You're testing at 13dpo, right? Fingers crossed for Friday then, we could do with some more good news!!

I have to say, the last two months the morning I've tested on 12dpo I've then had red spotting in the same FMU session, sorry for the TMI, which has been the herald of the forthcoming AF two days later. AF taking the mickey! I was wondering then this time if I shouldn't .. erm .. collect said sample and wait until I see if I get spotting at the end before using a test. May sound daft, but little point in testing if my body is telling me AF is about to arrive anyway!

stogan what a lovely update, thank you so much for sharing with us! How fabulous of your lovely DH, an eternity ring just seems to beautifully sum up the miracle of your wonderful baby girl. Just lovely!

free fabulous that you're feeling the movements of your little one, how reassuring must that be! Try not to rush around working too much, if that's possible :)

/waves to everyone

LOL choccy .. he's starting early with the quips! :)

Hey ari as I can't get in for a scan until I'm 7+1 (assuming I make it that far...) I shall test every few days to try to maintain calm/sanity/ manage expectations. It was still a shock to see an empty womb last time I want to be prepared even if I don't get any spotting/bleeding again... I feel quite detached ATM which is obv just auto protection. Whatever works!

Right must must do some work...!

Ahh, choccy, so pleased to read of your BFP. Fingers tightly crossed for you! Sorry to hear about your dad too, I hope he's getting stronger. Are they building him up for surgery?

PQ, sorry to hear you're feeling miserable. Could the brown spotting be from the same source as before? Sorry to hear you are suffering so badly with MS too. Hopefully it's a good sign but it's pretty rotten too. I had it pretty badly with a couple of mine.

I've not been on the thread for a good few days so there's lots I've not had a chance to properly catch up on. It's amazing though to see how many of you are in the 3rd trimester now!

Thanks for asking after me on Sunday. I was actually ok. I went to see my granny and auntie which was nice but also quite sad. My granny's grip on reality is getting looser by the day. She has been put back on the medication we were trying though which hasn't done anything for the confusion but she is not agitated and upset now which is at least something. On top of this she has something called Capgras syndrome which is a very surreal condition which really adds to the confusion.

I think my big emotional explosion was in part to be blamed on hormones. The SO treatment and then extreme PMT as a result. So, obviously the first cycle didn't work. I'm now on round 2. Waiting to OV sometime mid to early next week.

Lovely to hear from you stogan. Bet you have cramp in your face from grinning!

Hello all,

Gosh I am having real difficulties getting anything done today.

Kittens you are doing so well, with everything that has happened and is happening to you and the family. You have to remember that sometimes you are allowed to feel emotional - with or without the damn hormones and drug treatments. Really feel for you and your worries about your granny too.

PQ just try to remember that patch of bleeding was nothing to do with the baby and hopefully that is what has caused the brown stuff again. I do know people who have had full on bleeds for weeks and weeks and been fine. I know that doesn't help as we are somewhat special cases, and the people we tend to know that has happened to have not been rmc-ers but that patch of bleeding was there and proving pretty harmless so lets hold onto that. Roll on Thursday too.

Ari I think I am having a case of Choccy's PIWNIB as I can't get my head around what you were suggesting with the testing. But go for it! :)

Choccy you are bound to feel very cautious indeed. You could back away from the pee sticks so you don't go mad checking the depth of the line etc. But then I realise that you want to be prepared again if something is going wrong. Maybe this will be the time it all goes well though!!

Just got my results back from the docs and no urine infection (had suspected one). I am getting a bit of itching though and according to doc google that's something to do with the balance of the PH being out (vaginal ph to spell it out!). Says something about bicarb of soda or even sex as apparently sperm might rebalance things! DH is away tonight and I am away for 5 nights after that, so he has offered to pop some in the post

ROFL free ... surely he should courier it, to ensure total freshness? (thinking of kittens was it, with the courier a few weeks back?)

Sorry to confuse with my testing musings, it was just that AF has sent her spotting-herald on the morning of my HPT testing for the last two months so I was idly wondering whether I should save a sample of the next 12dpo FMU but wait to see if I get the spotting first before testing. Nothing worth really thinking about :)

ari, I know exactly what you mean. I have had that same "pee in pot, dip stick, watch with trepidations whilst continuing with erm, toiletting, wipe.... Ahhhh, ok.... hello AF"

In fact, you know how on the internet cheapie tests it says to let the wee and test stick reach room temp before testing? I've actually thought of putting the pot of wee in the cupboard to cool (how funny does that sound?) and then coming back to it a bit later. Meanwhile AF may or may not show up before wasting a test.

Mmmmm free, I hope there is not breakage of the vessel in transit! You could also try some of that Balance Activ or Fem Bio gel.

Yes, that was me with the courier. Although it ended up in my handbag on the tube in the end.