Meet the Other Phone. Flexible and made to last.

Meet the Other Phone.
Flexible and made to last.

Buy now

Please or to access all these features

Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

IVF/ICSI/FET - any more for any more?

999 replies

jumpingjackhash · 05/01/2012 10:05

Hi all, we're about to start FET following an unsuccessful round of ICSI last year (well, we got the bfp, but then I miscarried shortly after Sad). But... time to get back on the bike and go again...

Anyone else going through this?

OP posts:
ellangirl · 30/01/2012 20:41

Blimey, got phone call finally at 5.20pm saying I'm booked in 7.30 wed morning. Cue last minute dashing around to run to kennels and cattery(after catching the cats and dumping DS next door), and actually booking the blooming ferry which leaves first thing. Ovitrelle at 8pm, now just got to pack and we're good to go!!

CareBear1 · 30/01/2012 20:46

Knackered so sorry to hear that, how heartbreaking. Hope u take it easy over the next few days. Good luck to everyone else at your various stages. I've got to have more blood tests done then we'll be doing an fet round.

bugsylugs · 31/01/2012 04:38

rakkers great news fembie is on board hope you get plenty of rest and not too much mentalling
monkey good luck for this morning think

bugsylugs · 31/01/2012 04:39

Oops b phone. Meant to say thinking of you and baby dust for bfp
ellangirl hope all sorted and calm ferry journey

jumpingjackhash · 31/01/2012 10:54

Great news Rakkers, hope it goes well for your ellan!

Monkey good luck! [everything crossed emoticon]

OP posts:
zeebee1 · 31/01/2012 19:33

Hi all
Feeling like my AF is coming v soon - typical - just when i had an inkling that just maybe we'd skip the FET as we'd conceived naturally! Ha! Sorry - TMI all!

Knackered - so so sorry to read your news - what hard luck - this is all such a roller coaster emotionally at every stage - thinking of you and sending you positive vibes. Was that your first FET?

Rakkers excited to hear about your Fembie - fingers crossed for a sticky 9 months! I found the Zita west CD post trasfer v good during 2 WW - really does stop you mentalling (a bit!) too right re cold awakenings - jeeeeze it's artic out there!

jumping those side effects sound horrid - hope youa re coping OK?

Have good tues eves all
ZB

KnackeredCow · 31/01/2012 20:35

Thanks for kind words all.

Jumping hopefully I've made up the quota of frosties that don't thaw on this thread! I guess if I'd had a DET it could have still failed, but it seems really gutting that I only had one put back when there was only one to freeze, and there's a significant risk it simply wouldn't survive the thaw. Been doing quite a bit of digging around the subject and apparently clinics are supposed to consider the number of embryos available for freezing before doing an eSET because of those very risks.

Anyway, hope you're surviving on the meds and the side-effects are bearable. Not looking forward to another round of IVF and the medication required.

This whole fertility malarky just takes over life.

Ellan Best of luck for tomorrow. Hope you get lots of eggs.

Rakkers Really chuffed to hear that your replacement was successful. Hopefully the wait to test day is bearable for you.

Bugsy it's so tough isn't it when you lose an embie that may have survived if put safely back.

Chicken Really hope the increased drug regimen does work for you. I think IVF / ICSI is more an art than a science all the time. Really do hope you respond well. The injections get easier after the first couple of days. I don't think I was very good at doing them. Ended up covered in bruises, but it was a small price to pay!

Zebee We all hope for that last minute reprieve, don't we? It would be great to get it and not have to go through another cycle. Fingers crossed you do, but if AF does arrive at least it's helpful to know that the next cycle may well be fruitful. Yes, it was my first FET but only had one in storage as just two good quality blasts after IVF. One transferred, got pg but early mc. One frozen.

Well DH and I are being reviewed by doctor at clinic on Thursday and am going to dust myself off and book in for a (self-funded) IVF cycle. Looks like I'm stayin' on this thread for a while. Desperate to go again. It was devastating to lose the frosty BUT nowhere near as bad as the early mc.

Out of interest, does anyone know what their clinics policies on eSET are? Do they go for it still if you only have one to freeze?

CareBear1 · 31/01/2012 22:07

Just a small recommendation as some of you have mentioned zita west's meditation cd -if you've found that helpful try mindfulness meditation, particularly the body scan one by Jon Kabat-zinn. Its so relaxing and the only thing in years that's helped take my mind off fertility shenanigans.

monkeybumsmum · 31/01/2012 22:37

Thanks for your messages, but unfortunately it was bad news Sad It wasn't a surprise though, so when the call came we were able to discuss dates for the next round. I'm starting with the pill tonight, with a stimming start date of beginning of March. Off we go again...

KnackeredCow I'm really sorry to hear about your embryo not surviving. Our clinic always says there's only a fifty percent survival rate of frozen embryo's, but I'm so sorry to hear that this happened, you must have been devastated. Do you know when you'll start again, and what protocol you'll be on?

CareBear thanks for the recommendation, I'll have a look into that!

ZeeBee hope AF doesn't come!!

Hi to everyone else, I'm off to bed now - I'm feeling pretty emotionally exhausted tbh Sad

bugsylugs · 31/01/2012 22:39

knackered I am sure you have said but how old are you. Care were very happy for me to put 2 back their preferred option I could have put 3 back as old G.
Hope evryone ok not posting more am in some discomfort and similar to last m/c think products stuck in cervix sorry prob tmi. will call epau tomorrow if no change. SAU covers at night so not keen to go there.

KnackeredCow · 01/02/2012 08:04

Monkey So sorry to hear that things didn't work out for you Sad

Good that you've got your next start date though, not that it's really much consolation. We're seeing doctor tomorrow for a review and he'll book us in for next cycle. Don't think it will be Feb as our clinic is fully booked at the moment, so that's irritating. But you never know. Opted not to see our consultant but to see the reg instead as was two month wait otherwise and I did well during IVF so they'd already said no need to change that. I'll be doing the short protocol again.

Bugsy Really sorry to hear you're in so much discomfort Sad. Hope you're coping OK for now. Thinking of you at this time.

I'm only 33 hence clinic's reluctance to do a double blast transfer. I would go for an eSET again (because I did get pg), but only if we have a minimum of 3 top quality blasts for the freezer left over after fresh replacement. The risk of loss during the thaw process is unacceptably high to me now.

lizziebennet · 01/02/2012 12:28

This reply has been deleted

Message withdrawn at poster's request.

ellangirl · 01/02/2012 14:06

Hi lizziebennet, I think if there were only 2 at day 2, all clinics would put them both back. eSET is mostly recommended at day 5 transfer because they can be more sure of the quality and therefore choosing the best single one. Doesn't mean your day 2 transfer won't work, they just don't go to day 5 unless they have at least 4 or 5 good ones at day 3 because they don't want to risk them all arresting and not having any to put back. good luck with testing when will that be?

I just had EC this morning. They had expected 16 ish eggs, but in actually fact there were only 11. Am concerned and disappointed because last time I had more eggs(15), and there was still only one early blasto by day 5. Ah well, tis done now so keep your fingers crossed and play the Barry white tunes for my eggs and dh's swimmers to get doing their thing overnight!!

Interesting discussion about single transfer and freezing. I had lovely chat with embryologist today about this, as she said a good result as far as they're concerned would be one blast to put back and one to freeze. I asked about survival rates for frozen and she said 80%, and with a 30% ish chance of pregnancy from that single one. Basically, if we only have 2 left, I want them both in (I'm 28 so they're pushing eSET, but I get the feeling that with one failed cycle behind us, they're more willing to consider det). I'm not prepared to take the risk of paying for more drugs, plus travel etc to find it hasn't thawed. I can see on here how hurtful that is. We are at gcrm in Glasgow by the way.

Busy sorry you're in pain, hope you feel better soon Brew

ellangirl · 01/02/2012 14:07

Bugsy even. Damn autocorrect!

lizziebennet · 01/02/2012 14:53

This reply has been deleted

Message withdrawn at poster's request.

ellangirl · 01/02/2012 16:16

Just heard all 11 were injected successfully. Is your cycle funded lizziebennet? Strange that. But if an embryo is meant to make it, it will, and prob do better inside you than in a lab Grin. Clealy I hope you don't have need of it again in the future, but I cannot fault gcrm for their service and treatment so far, if you're ever looking for somewhere else to try!

jumpingjackhash · 02/02/2012 09:57

Hi there, it's interesting (but a bit depressing) to hear the variations on thaw success rates with FET. We were told around 70-75%, so it seemed like a good enough chance, although DH is now wondering if we should have just gone for the full icsi cycle this time. Helpful for him to consider this NOW, just as I'm feeling particularly shitty thanks to the drugs! I swear it's taking all my strength not to blow atm! Blush

OP posts:
lizziebennet · 02/02/2012 10:57

This reply has been deleted

Message withdrawn at poster's request.

ellangirl · 02/02/2012 13:55

Only 7 fertilised. The drop off rate is traumatic isn't it!
Jumping if you have the frosties there, it seems right to give them a chance. It is a good chance. How many do you have frozen? I just heard today that a friend has a bfp following a double 3 day transfer of not very good quality embryos after thaw. Goes to show you anything's possible!!

zeebee1 · 02/02/2012 15:15

Oh hello there AF - how delightful to see you this month (NOT) Angry How silly of DH and I to think we would just maybe not have to start the FET route afterall.... argh. So I guess i'll be ringing Guys tomorrow morning and arrange for drugs to be delivered so I can start the sniffs.....

jumping do you start sniffing on day 21 of your cycle? I hope you are OK -I hate thinking about all the "what ifs" and "buts" it's something that we can't control I guess - and that's why it's SO frikkin frustrating! My DH always tries to cheer me up by saying - we've come through the worst of it - and i just say - how do you know the worst could still be yet to come - so it's happy days in our house [humm]. I think you've just got to have faith in what stats Guys tell you and believe...

So many of our friends and members of the family seem to be having babies at the moment and I am forever going out in my lunch hour and buying YET another baby card - makes me feel even worse on bad days.
sorry - rant over !

welcome to lizzie and congrats for getting this far - only another 8 days til you test... that's not too long. Monkeysbum how are you doing?

ZB

ps - Biscuit's and Brew for all from me

lizziebennet · 02/02/2012 16:19

This reply has been deleted

Message withdrawn at poster's request.

KnackeredCow · 02/02/2012 16:57

Hello all

Lizzie I agree with ellan that the eSET policy is mainly applicable to day 5 blast transfers at most clinics. As yours was a day 2 transfer, I'd try not to worry (much easier said than done though)! Fingers crossed you get a bfp. If the worst happens, and you don't, it's great that you get 2 NHS cycles.

Ellan 11 eggs is really good. It's higher than the average they get at the clinic I'm with. And it is quality, not quantity that counts. 7 fertilisations is really good too. That's over 60%, which is great for ICSI.

Jumping There is a really good chance yours will successfully thaw. I was really unlucky, but like you say, the variability in thaw rates does make you think. At least we're all asking the question of our clinics now.

ZB completely with you there about the trauma of buying new baby cards. It's so tough isn't it.

Well DH and I got reviewed by doctor at our clinic today after failed thaw on Monday. He was absolutely lovely and said he would feed it back to the embryologists that we hadn't been told the significant risk of a failed thaw. He said that although we consented to eSET before the cycle, the clinic should have reviewed the decision with us prior to ET. He did say that we'd still have been advised to go for an eSET. However, he was also quite critical of the HFEA and said there is a target on all clinics to reach a 10% multiple birth rate this year, and he implied that clinics get fined if they don't meet it. Shock He also said that the PCT wouldn't necessarily fund DET, so it was unlikely we'd get very far if we did complain as we were on a funded cycle.

We discussed the risks involved with a multiple pregnancy and twins. I pointed out that the absolute risks are still quite low and that only talking about relative risks can be misleading. DH told him that he found the language that had been used very emotive and not appropriate for allowing informed decision making. For example, before our first cycle of IVF we were told, "the perinatal mortality rate in twins is double that of singletons". DH said that perinatal mortality is actually quite low, and then pointed out that double is still pretty small! Doctor agreed and said a lot of the statistics and language used are misleading because basically the cost of caring for those twins who do have problems has been linked to the increased rate in twins due to IVF. He also said that lots of twins are perfectly healthy.

Once we demonstrated that we understood and accepted the implications of having twins, he said he fully supported our decision to have a DET! So plan is now in place for next round; DET if 3 or fewer top quality blasts and eSET plus frosties if 4 or more.

And then we got incredibly lucky and got a cancellation slot for a fresh IVF cycle. We start on what would have been test day! So - never thought I'd hear myself say this - roll on AF, which is due a week today!

Gosh - sorry for mega post but feeling much, much better about things now.

zeebee1 · 02/02/2012 17:42

Great news knackered sounds like you had a very good chat with your consultant. So true re DET vs eSET. We um-ed and ah-ed before decided to go with 2 embryos first time around because we felt Guys were pushing for us to do eSET, but with my grand age (38 then (39 now Hmm)) and that we really pushed that we wanted DET they let us. PLUS we have 2 lots of friends with IVF twins and they had perfectly normal births and their twins are all fine and healthy... phew! Great you begin your course so soon as well - BRILL!
ZB

ellangirl · 05/02/2012 12:08

Hello all, how are you? Knackered glad you get to start again soon- not often you look forward to af arriving!
I had transfer yesterday, as it happens a double 3 day transfer of an 8 cell top grade, and a 7 cell, there was only one other decent one at day 3- another 7 cell, so it wasn't recommended to go to blasto. They're culturing on the other ones to see what haooens. Interestingly the doctor who did the transfer has just been cited in articles saying women should get more choice as to whether they get one or 2 embryos transferred.

FatimaLovesBread · 05/02/2012 19:57

Hi everyone

Just been catching up on everyone's situation. That's great news about the DET knackered! I'm worried that our clinic will push for eSET as i'm only 25 but would rather have DET, is it only really relevant when looking at Blastocyst transfer?

I got my drugs delivered on Tuesday and have my prep appointment this Wednesday then just have to wait for AF to arrive so I can start stimming. AFs due on the 17/18th but last month was 4 days late so really hope it comes on time or early this time