IVF/ICSI/FET - any more for any more?

[jumpingjackhash]

Hi all, we're about to start FET following an unsuccessful round of ICSI last year (well, we got the bfp, but then I miscarried shortly after ). But... time to get back on the bike and go again...

Anyone else going through this?

Oh Care . Really sorry for you. Is your DH there with you?

Really sorry Carebear - it is just not fair. xxx

So, so sorry Carebear. Absolutely dreadful news. I don't know what to say, but very saddened to hear it didn't work.

Take time off work if you need it. It's important to look after your health and wellbeing at times like this.

Thanks guys, that's really sweet of you - and it helps to know other people understand, and care! x

Duggs, am just thinking through next steps, and you said you didn't mind questions, so do you mind if I ask, if I wanted to estimate how much it might cost for all appointments, tests and drugs to see Mr S and go through say 3 cycles on his plan without ivf (is that super-ovulation?) how much ballpark would you say that would be? Also these tests for NK cells and things, are any of them ever available from the GP, do you know if its worth me going to ask and if so what the tests are called?

thanks, x

hi care .. ok well yes the immunology theories do apply to IVF implantation failure too so I can see why you are asking.

GP should do as many tests as possible - the usual for lupus, blood clotting disorders etc. NHS won't recognise NK cells (unless you are lucky enough to have a consultant that practices this)

Dr S - £300 initial appointment.
£300 for NK cells test.

Then if you do have elevated cells his programme offers an 85% success rate.
There is a thread on mumsnet called TTC pregnancy on prednisolone -there are 6 threads and about 30-40 women on them. Half are pregnant on his programme and half are still TTC. Some via IVF, some via Super Ovulation and some naturally. Many have children already and have had a number of miscarraiges since or failed IVF.

A typical SO cycle is about £50 for letrozole (like chlomid) and ovitrelle and then £200 for Dr s mid cycle scan and ovulation.

I would recommend you have the nk cells test before you try another cycle esp if your blasto or embryo was a high grade and uterine lining healthy.

Any questions any time just ask.
Massive hugs. You will get there. It won't feel like it now but you will x

Thanks for this duggs. We were told all our blastos were of good quality, and now 3 have failed to implant. The lining was not bad, just about 8 mm on the last scan prior to transfer which i don't think is very big, but ok? Who knows but sounds like its worth investigating, I think I will give it a try.

Ok care so u know u can get good quality eggs out that is excellent news as that is something more difficult to fix. Seed and soil analogy. the soil now needs looking at. If lining thick then it very well could be immune issues. The more failed attempts the more active the cells can get. Do y suffer with many colds etc recently? If not that be an indicator. Super duper immune system. Is treatable. You should get appointment quickly enough either in Harley st or Epsom. X

Hi Carebear - hope you managed to get some sleep - you must be absolutely exhausted . Agree with duggs - perhaps some other issue - and perhaps would put your mind at rest if you do more tests.
On the other hand it might simply have been there was nothing wrong and you just haven't had a lucky break yet - don't give up hope and try not to panic (easier said than done I know) xxx

Care I am so so sorry to hear your news. Please look after yourself and come and have a rant if you need to ((hugs))

A friend of mine who's been trying for her second for 4 years (PCOS) has just been told that the clomid isn't working and they can't do anything else for her. She needs IVF but they won't offer it. She's devastated

I actually had some good news yesterday, sorry for not filling you all in earlier. The scan showed that my lining has thickened up 1.8mm since Sat, one follicle has only grown a little bit, but the other has grown 2mm since Sat. The dr still wanted to cancel but we pushed tot ry more and they've said that IVF isn't an option now as we only have 2, but they will consider IUI if the follicle grows to 16mm!! I was so happy they didn't canel the cycle! I think the nurse had to fight our corner (we didn't actually speak to the dr ourselves) so we're still going. There was another, 5mm follicle which the nurse said she didn't think had grown, but I've got another scan tomorrow and if it has grown, and the others have too, I'm going to push to continue IVF.

Just popping in to send hugs to carebear so devastating. Give yourselves some time. Sod work. Thinking of you

Glad you're getting some more positive news Josie - keep us posted!

Josie - good news you must be pleased.
Care - hope you are feeling ok today? Thinking of you...

Afm: just had scan and womb is still not thick enough - so I'm now on the lovely patches! Another scan next week so maybe FET w/c 9th April... Fingers crossed! This is the looooongest build up ever! At least it's sunny outside and I have a morning off work so going for a wander and a coffee somewhere nice.

Hi care thinking of you today.

Josie that is good that you have had some postive news, make sure you keep fighting your corner.

Zeebee My fingers are crossed that your egg collection will finally be w/c 9th April, hope you enjoyed the sun and your coffee this morning.

Sorry Zeebee that was supposed to say egg transfer not egg collection, oops

Thanks lumili - just boring to yet again be waiting! Still I am certainly enjoying the sunshine - mustnt grumble
X

zeebee That is one of the worst things with IVF - the waiting!! However, at least are going along in the right direction and you will get there in the end :) Glad you are enjoying the sunshine :)

Good afternoon everyone!
It?s so blooming sunny, I love it

Carebear I know that you?ll be feeling devastated, but I am thinking of you and sending you lots of love.
As I have been reading, it sounds as though you have the good ingredients to make your little cherub, it?s just the frustratingly illusive timing we?re all hankering after. Chin up chick, it will come right soon, you'll see x
On a personal note: Thank you for your YouTube link, it brought a tear to my eye. DH and I have been texting each other (since watching the film) that we?re going to be creating ?a real human being? ? And so (in true TTC nature) of course this is now a sign!

It is great news that our stubborn perseverance avails again Josie! Don?t let them bully you into bending to their way. It?s your body and you should decide what happens.
I won?t claim to know much about the different protocols, but I am with Lumili ((waves)) in that Knackered ((waves)) is like the oracle of this thread and gives the best advice, but carebears comment re older processes is worth investigating too. Wishing you the most luck x

Jumping/Karbea I hope you two are managing to stay sane? Thinking of you!

Has anyone heard whether Millymoos DH is ok? Did he survive the weekend
I hope you?re well and managing to channel that irritation x Good luck for the scan on Thursday!

Raspberry How are the embryos doing? x

Sending lining thickening vibes hate that word, erm, energy to Zeebee -
Apparently, if you rub just under the medial malleolus here?s a link
This is suppose to encourage bodily fluids?

I am in good spirits today, and tbh have been throughout down regulating, but today we were given the go ahead to start stimulating on Thursday. Apparently, I have down regulated. Hurrah!
Anyway, so if anyone needs me I?m currently taking residence on cloud 9 .

Hello all... care I see u posted on ttc pred thread. pebbles should reply she had a couple of failed ivf cycles then saw dr s and was diagnosed by him. Lurking for news from raspberry on her CGH embryo results?!? Waves everyone else

Zeebee fingers crossed your lining thickens soon, the waiting must be awful

Angel hurray for starting stims soon

Waves to Duggs

Isn't it strange how singing and dancing along to loud music playing in the house can make you forget all your worries for half an hour! I highly recommend it :) Apologies if you all think I am mad . Just thought I would share it with you.

Hi all - thanks so much for all your messages. Lumili please share the songs!! Anything that makes you forget ttc and dance around like a luny sounds good. I will now think of you as Luny Lumili!

Duggs I have been proactive today and got an appointment with Mr S. I feel like its worth exploring every avenue at the moment.

Josie that's great news, well done you for sticking with it and not giving up. I'm sure that's the spirit that will help us all get there in the end.

Zeebee sorry for more waiting - just think of it as extra preparation time to create the perfect environment!

Angel so glad you love that song too - that film really got to me and this song is just stuck in my brain at the moment and seems to go straight through me. My only complaint is its too short, I keep having to press play again.

Yes Raspberry what news? Do you mind if I ask, is the CGH just because of a previous result? I was wondering how you knew to have that tested. I'm sure you said it in one of your previous posts and I'm just being lazy and not reading back through.

Question: If we had 6 embies that made it to blasto stage, does that rule out chromosome issues or is would implantation failure also point to possible chromosome issues? I'm so clueless on this topic.

Raspberry though i do agree - could just be one of those things. I'm just having those maddening thoughts of trying to work out why!

Jumping and Karbea hope you're getting on ok, thinking of you.

LizzieB well i should be bleeding again soon so we can rant on here together!

Hi Millymoo, what news?

Well overall today - I could have been worse. My mood today reminded me of.....my 5 yr old self with grazed knees with a wobbly bottom lip trying to be very brave and not cry. Made it through the whole day at work and have got on with organising things for next treatment round. I'm lucky to have more treatment left on the NHS, and we have 3 blastos left in the freezer so am just trying to concentrate on that. Oh and we're going to go camping and cycling for a weekend which we wouldn't have done otherwise. Hmm, am typing this to try to convince myself! Actually part of me feels like this is mile 22 of a marathon and i just want to lie down in the road. sigh. Anyone else?

Hi to anyone else i missed. x

Oh and some words of wisdom from my Randine Lewis meditation cd - don't hold on to the hurts. You have to let them go, otherwise they create dark patches in your heart. You have to open your heart, let the hurts go, and let the pretty pink light in.