Breastfeeding and eczema research
Posted on 24/08/2011

A worldwide study led by King’s researchers has found no clear evidence that exclusive breastfeeding for four months or longer protects against childhood eczema.

The findings, published today in the British Journal of Dermatology, have prompted the researchers to call for a review of the current UK breastfeeding guidelines with regards to eczema.

Conducted by researchers at King’s, along with the University of Nottingham and the University of Ulm, Germany, the study looked at data from 51,119 children aged eight to 12 from 21 different countries. 

The research was carried out by gathering information on eczema, breastfeeding and time of weaning by parental questionnaires. Children also underwent a skin examination for eczema and skin prick testing to environmental allergens, including house dust mite.

Earlier studies have suggested a protective effect of breastfeeding on childhood eczema, and the UK Department of Health currently recommends exclusive breastfeeding for six months to prevent eczema, in line with the World Health Organisation. However, a review of the more recent literature found no evidence for a protective effect of exclusive breastfeeding for three months or longer on eczema development, in keeping with the findings from this study.

The authors also point out that there is mounting evidence to suggest that the early introduction of potentially allergenic food proteins, such as peanut, could increase tolerance to these foods, rather than causing allergy, although this remains to be confirmed in intervention studies.

This worldwide study therefore sought to investigate to what extent exclusive breastfeeding protects against childhood eczema. It concluded that children who were exclusively breastfed for four months or longer were as likely to develop eczema as children who were weaned earlier.

The research was part of Phase Two of The International Study of Asthma and Allergies in Childhood (ISAAC), the largest epidemiological research project ever undertaken. 

Dr Carsten Flohr from the Asthma, Allergy and Lung Biology Division at King’s said: ‘Although there was a small protective effect of breastfeeding per se on severe eczema in affluent countries, we found no evidence that exclusive breastfeeding for four months or longer protects against eczema in either developed or developing nations. 

‘We feel that the UK breastfeeding guidelines with regard to eczema should therefore be reviewed. Further studies are now required to explore how and when solids should be introduced alongside breastfeeding to aid protection against eczema and other allergic diseases.’

Dr Flohr added: ‘It is widely accepted that breast milk is the most important and appropriate nutrition in early life. Especially in the context of developing countries it is also important to keep in mind that exclusive breastfeeding reduces the risk of gastrointestinal infections compared to mixed or bottle feeding. Our study does not change this notion.’

Nina Goad of the British Association of Dermatologists said: ‘The size of this study means that its findings are very significant, although the authors recognise that further studies are required. Following these further studies we may need to review the UK’s advice on how long mothers should breastfeed exclusively for, and at what age we should be weaning our infants, in relation to eczema prevention.

‘This study isn’t about the benefits of infant formula milk versus breast milk, nor is it questioning other benefits of breast feeding, but it is about whether breastfeeding exclusively for prolonged periods and weaning after six months, as opposed to after four months, has any impact on eczema risk.’

For more information please contact Emma Reynolds, Press Officer at King’s College London, on 0207 848 433434 or at [email protected]uk.

Notes to editors: 

The paper, ‘Lack of evidence for a protective effect of prolonged breastfeeding on childhood eczema: Lessons from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two’ is published in British Journal of Dermatology and can be viewed online at www.brjdermatol.orgg.

The Scientific Advisory Committee on Nutrition (SACN) is currently undertaking a review of the scientific evidence underpinning the United Kingdom infant and young child feeding policy, stating that since the Committee on Medical Aspects of Food Policy (COMA) published its report ‘Weaning and the weaning diet’ in 1994, there has not been a thorough risk assessment of such evidence in the UK. (www.sacn.gov.uk) 

ISAAC, The International Study of Asthma and Allergies in Childhood, is a unique worldwide epidemiological research programme established in 1991 to investigate asthma, rhinitis and eczema in children due to considerable concern that these conditions were increasing in western and developing countries. ISAAC has become the largest worldwide collaborative research project ever undertaken, involving more than 100 countries and nearly two million children. Its main aim is to develop environmental measures and disease monitoring in order to form the basis for future interventions to reduce the burden of allergic diseases, especially in children in developing countries. 

For more information about King’s, see the ‘King’s in Brief’’ page.
Errr no mainly