Hi all
Jardins, I'm afraid I haven't really had the runs - I'm more the other way. But, when things do move and I do have to go, I really have to go right then, and, erm, despite feeling constipated, am softer than normal. Sorry if that's TMI, but you asked!
On the amnio front, I don't know what to say, it's all such a tricky subject. Is 1 in 344 a risk based on bloods or a combined test, or is it your background risk for your age? My background risk is 1:450 (or thereabouts), but I had the combined test (nuchal measurement, combined with weight, age and bloods) and was adjusted to 1:8700. So, I suppose I would say if you are just going by your age, and you are concerned, then try and get an adjusted risk? My information said that the combined test picks up 95% of high risk pregnancies, with the blood test alone picking up only 65%. But you've got to do the nuchal measurement before 14 weeks I think.
Erm, I'd also say that you only had a 1 in 8 chance of your pregnancy reaching this point - don't know if that helps put into perspective the kind of risk 1 in 344 is? It's still very small in percentage terms (0.3% if I've done my sums right), while the amnio carries a risk 0.5%to 1% of spontaneous miscarriage. And I think I'm right in saying that an amnio still only gives you a probability, not a definite answer. I think a chorionic villus sampling is more accurate, and carries a similar risk of miscarriage. I also believe that you can get stats for particular clinics, so you can choose to go somewhere with a low miscarriage rate.