While I understand what you are saying about not judging people based on partial information, it seems to me that Knox is actively courting judgement of her personality through the TV dramatisation and the comedy show (admittedly based on the very short clip I have seen of the latter).
The TV series is certainly all about her "quirkiness" as she calls it - it reverts to this theme time and time again, the message seeming (to me) to be that other mere mortals - people who are not her - simply can't comprehend and handle how hilarious, out there and zany she is. Just as one example, there is a brief scene of her in a restaurant with Meredith Kercher and her English friends (all characterised as hysterical, up-tight fools) in which Knox picks up her plate and licks it clean, and the other young women look at her askance - as well they might, surely? I'd be irritated and a little revojted is somebody did this when I was out for a meal with them. But we are supposed to feel that they were judgemental twats for feeling like this.
There is also a later scene when Knox speaks quite cruelly to one of the young English women who is sobbing - again, it seems we are supposed to side with Knox, for being a hard talking realist brave enough to tell it as it is - to me she just seems unnecessarily nasty.
My point is, in this instance I make no apologies for making a judgement on Knox's character because that's what she's inviting us all to do! Mine just isn't the judgement I think she wants us to make.
And of courses I don't think she should have been vilified for having sex toys or an active sex life. I don't think she should be vilified at all - she hasn't done anything evil.
But much as I feel sorry for her, I also think she is an unpleasant, not very bright attention seeker, and that a comedy show linked to a brutal sex murder is massive error of judgement, and offensive not just to Kercher's family but potentially to all victims or sexually motivated violence, and those who love them.
I don't think she should be silenced. But I do think she should have exercised better judgement, and that if she believes it's important to have her story heard, she could have chosen more appropriate ways to achieve this.