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Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder if there will be any fall out from skinny jabs?

1000 replies

TheLemonGuide · 20/04/2026 16:40

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

OP posts:
Binus · 05/05/2026 17:10

I think this argument does need to acknowledge that some of the developments in Western society that lead to a change in the number of calories taken v burned are unalloyed positives that it would be bad to try and reverse. Like better quality heating and fewer people engaged in hard manual labour.

Backawayfromthesausage · 05/05/2026 17:11

Whoknows101 · 05/05/2026 17:02

I agree with you that it is biological in the sense that it's pretty obvious that there is a large proportion of the population that have a significant physiological propensity to obesity in the "right" conditions. Which is why many individuals are now left with no choice but to medicate themselves because they have no other option.

Where we seem to disagree is that I think it's equally obvious that the conditions that have revealed this propensity and caused the current epidemic are predominantly socio-economic / environmental in nature. Such as the vast, unrestricted supply of unhealthy food advertised & cheaply available to us from a young age, for example.

It’s just not that simple. People get fat by eating roo much,not simply as they eat the wrong foods, simply the world and us in it evolved.

But I’m failing to see the issue, the horse has bolted. if a safe drug comes out which helps people resolve it then that’s great, food retailers are already seeing a huge movement away from unhealthy foods.
and in the 60s people were doing drugs ti stay slim. And smoking. It was not some golden Eutopia full of healthy people eating small portions of healthy food. It was an era filled with smokers, many taking drugs to become smaller. With some real dodgy drugs coming to market. Fortunately eventhing has tightened up since them, people consumed so much more alcohol . You could drink drive. There was no safe limits in weekly consumption till the 80s.

the world evolves./

Witchonenowbob · 05/05/2026 17:12

JacquesHarlow · 05/05/2026 16:53

Aye, so you are ! Entirely pissed off that fatties are now thin more likely

Oh look, it's another poster who needs to believe that us lifelong "thin" people are annoyed that overweight people can become thin.

Breaking news to you - I don't care what your starting position was or your finishing position. I repeat what I said: I am genuinely happy for you.

And good lord - I have not displayed ANY rage or angst.

none.

Don't use emotional words to try and paint me as unreasonable, when I have not used any myself other than positivity.

I have calmly put forward a few arguments and then watched as the predictable onset of emotional language was sprayed at me.

This reply of yours, and others, is more proof to me that people on this thread want to vehemently shut down anyone who tries to raise any argument other than "the jabs are the best thing ever and we wouldn't have had an option otherwise because we tried everything".

Calmly put forward an argument??

To remind you, you said

They will find and forensically take apart any evidence, anecdotal or otherwise.
There is a cult-like fervour in this country in the UK for these drugs, led by people who would never have been able to achieve a successful weight loss outcome otherwise.

Hardly calmly, in fact very inflammatory and very demeaning about people who use WLI.

SilenceInside · 05/05/2026 17:13

The outcome might be seen as dystopian, but it comes from a set of fairly fundamental concepts for survival - to have abundant food available and to minimise energy outlay. Those are excellent strategies for animals in their environment, to ensure their survival, successful reproduction and survival of any offspring. Humans have just been far too successful at it, in some parts of the world - usually at the expense of the other parts.

Backawayfromthesausage · 05/05/2026 17:17

another example is in the 60s, 50 percent of the population smoked. 50. Now it’s 10. To try to pretend 60 years ago we were all slim and healthy is nonsense.

whall we do, put everyone back on the fags, as smoking declined, obesity increased. It all contributes.

ChunkyMonkey36 · 05/05/2026 17:23

Backawayfromthesausage · 05/05/2026 17:17

another example is in the 60s, 50 percent of the population smoked. 50. Now it’s 10. To try to pretend 60 years ago we were all slim and healthy is nonsense.

whall we do, put everyone back on the fags, as smoking declined, obesity increased. It all contributes.

I’m obese and smoke, so that puts that theory out.

Unless of course I was just very good at getting fat in spite of the fags!

Binus · 05/05/2026 17:30

I was thin when I smoked and didn't become obese til after stopping! Some of our bodies are just plain awkward.

But nicotine is an appetite suppressant. Obviously it doesn't work on everyone, like WLIs don't, and it's also possible for any effect to be outweighed by other factors. It does however mean that it's a factor needing to be taken into consideration when making comparisons. The UK didn't start counting smoking rates til 1974, but it wasn't far below 50% then and everything I could find suggests it was dropping before that. If we're comparing the 2020s to the 1960s, of course half or even a majority of adults taking an appetite suppressant regularly is relevant.

Backawayfromthesausage · 05/05/2026 17:32

ChunkyMonkey36 · 05/05/2026 17:23

I’m obese and smoke, so that puts that theory out.

Unless of course I was just very good at getting fat in spite of the fags!

Edited

I didn’t suggest everyone who smoked was thin, there has always been fat smokers. What I was saying is smoking for many is an appetite suppressant and it’s well know that stopping has led to weight gain for many.

InfoSecInTheCity · 05/05/2026 17:46

ChunkyMonkey36 · 05/05/2026 15:46

Why would anyone be pissed off because someone else who was fat is now thin?

Surprising a it’s not that uncommon, I have ‘friends’ who since I’ve become one of the thin ones no longer invite me on shopping outings, the only thing that’s changed about me is that I can actually fit into the clothes in the shops they want to visit now and look good in them. I very rarely talk about my weight and if anyone says anything I just thank them and redirect the conversation back to them because I don’t want to become a diet bore. So I have to assume I was fulfilling some kind of ‘fat friend’ role in their lives making them feel better about themselves.

Usernamechanging · 05/05/2026 18:40

There is a cult-like fervour in this country in the UK for these drugs, led by people who would never have been able to achieve a successful weight loss outcome otherwise

Absolutely. And it's fucking amazing. It works. It really works. I am not as fat as I was and am reducing further. I am down 5 (count 'em!) dress sizes. Another 2 to go. What on earth is wrong with that? Do you really want me to continue as a morbidly obese person when there is an alternative I am able to afford? Why does it bother you so much?

icecreamflowers · 05/05/2026 23:35

Have not yet found the article I read that stated 100 cases of sudden blindness in people taking WLI in the US. However, found this in another article:

In addition, USA TODAY’s review revealed at least 110 plaintiffs across both the federal and state lawsuits allege the drugs caused sudden blindness or severe vision changes,

GLP-1 weight-loss drug lawsuits allege serious side effects

These are allegations, yet to be proven in court. But both the WHO and the EMA seem to think there is a causative link and risk of NAION with WLI, and recommended the rare risk be added to updated product information back in mid-2025. From the WHO:

The use of semaglutide medicines and risk of non-arteritic anterior ischemic optic neuropathy (NAION)

SilenceInside · 05/05/2026 23:45

No they don’t think there’s a causal link, the additional warning is an extremely cautious response to a possible correlation. In the same way that there was a mention of specific types of thyroid cancer even though there has not been a single case of thyroid cancer that’s been linked to GLP1s. It was based off one toxicology study on rodents.

icecreamflowers · 05/05/2026 23:54

They don't think there is a causal link?

The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) reviewed all available data on NAION with semaglutide, including data from non-clinical studies, clinical trials, post-marketing surveillance and the medical literature. PRAC concluded that NAION is a very rare side effect of semaglutide, potentially affecting up to 1 in 10,000 users.

icecreamflowers · 06/05/2026 00:13

Binus · 05/05/2026 15:13

I can believe you didn't invent the at least 100 figure yourself (mentioned!), that it came from someone else, but we have absolutely no reason to place the level of trust in them that you do. And this is not your first convenient failure to back up a claim.

It's a bit concerning that you think anyone daring to question your beliefs and unverified assertions is belligerent.

So sorry, unable to find the 100 figure article. Found an article, see post above, that states 110 known of.

Backawayfromthesausage · 06/05/2026 06:52

icecreamflowers · 06/05/2026 00:13

So sorry, unable to find the 100 figure article. Found an article, see post above, that states 110 known of.

people are not disputing there are people suing and alleging the drugs caused their eye strokes. People have disputed your statement a hundred people were blind due to the drugs, it has been pointed out to you multiple times this is absolutely not a given. The number of plaintiffs does not change this. If you’d said there is a hundred very unwell people who were at risk due to there obesity and diabetes suing the manufacturer in the USA as they allege the drugs caused it, not their weight and health conditions no one would have pushed back at you.

i also don’t have any idea where you’re going with this. There is over 50 million people on the drugs globally, yes, 100 or so people in the USA allege the drugs caused it, the only 100 of the 50 million.

it may have increased the risk, it may not. The fact remains, these people were at risk anyway, and at risk of even worse health effects due to their weight and health conditions,

the law suit is also that the manufacturer should have warned there was a tiny increased risk of a very rare side effect, something if you read the documentation will be very hard to prove, because 100 out of 50 million is so tiny and again, these were very unwell people in the first place.

MoneyJo · 06/05/2026 06:54

icecreamflowers · 06/05/2026 00:13

So sorry, unable to find the 100 figure article. Found an article, see post above, that states 110 known of.

So that's about semaglutides (although the post by @SilenceInside at 23.45 is important on this). Nothing about tirzepatides then?

Plasticdreams · 06/05/2026 06:55

Mithral · 20/04/2026 16:53

Injecting yourself is not a big deal - lots of conditions require this.

I had to inject myself for a few weeks after having a c section

IDontHateRainbows · 06/05/2026 06:55

Binus · 20/04/2026 16:56

They do. And the NHS already relies on people to do a loooooot of self reported things with no/minimal supervision. Many of us have experience of being asked to take our own blood pressure, weight and the like. If that's a risk, it's one that goes well beyond merely WLI users.

Although I can't see that we've anything like enough HCPs to stop being able to take people's word for a lot of things in healthcare.

There are virtual wards in most hospitals now aka patient stays at home and reports their vitals to a team of nurses sat in hospital.

Tattletale26 · 06/05/2026 07:05

Ukefluke · 05/05/2026 15:36

"Genuinely happy for them".
Aye, so you are ! Entirely pissed off that fatties are now thin more likely

""What I find fascinating as ever is the sheer passion and anger that some on here will argue with, in support of these weight loss jabs"".

Hm, what I find more fascinating as ever is the sheer passion and anger that some on here will argue with, AGAINST these weight loss jabs.

Such rage and angst about a medication they dont take.

This. They're furious that fatties have found a true solution that genuinely works, and desperate for the other shoe to drop.

It's quite satisfying actually watching their bitchy hatefulness thwarted:)

I lost nearly three stone on mounjaro, it was dead easy with the jabs and it's stayed off for a year, using maintenance shots.

The day after I started taking it, I immediately felt no nausea, inflammation went down, had far more energy than usual and food noise - which is VERY MUCH a real thing - vanished.

Zero negative side effects 18 months on.

Fabulous outcome and very satisfying watching them wail and gnash their teeth 😁

Witchonenowbob · 06/05/2026 07:10

icecreamflowers · 06/05/2026 00:13

So sorry, unable to find the 100 figure article. Found an article, see post above, that states 110 known of.

Your posts are about allegations?

Any actual facts?

Witchonenowbob · 06/05/2026 07:14

Tattletale26 · 06/05/2026 07:05

This. They're furious that fatties have found a true solution that genuinely works, and desperate for the other shoe to drop.

It's quite satisfying actually watching their bitchy hatefulness thwarted:)

I lost nearly three stone on mounjaro, it was dead easy with the jabs and it's stayed off for a year, using maintenance shots.

The day after I started taking it, I immediately felt no nausea, inflammation went down, had far more energy than usual and food noise - which is VERY MUCH a real thing - vanished.

Zero negative side effects 18 months on.

Fabulous outcome and very satisfying watching them wail and gnash their teeth 😁

Well done! Pleased for you!

I bet you are loving your new self? Enjoying life? Sprung in your step?

That’s what pisses people off!

It’s a great breakthrough, long may you reap the great benefits.

Backawayfromthesausage · 06/05/2026 08:00

I do wonder what the objective is from these posters posting misinformation. These threads are constant, and I strongly suspect it’s the same small handful of posters haunting them posting negatively. Negativity is fine, but it has to be factual. If someone posts false information it will be corrected. Accusing people of nit picking when that happens, it’s just bizzare.

they can’t think they will stop the roll out of the drugs or restrict people getting them, they can’t think they can stop people taking them. So what’s the objective. Burst the happy bubble of people on them due to uncontrolled spite and envy?

I can fully understand if you are fat and can’t access them why you’d be jealous. I can also understand if you struggle to maintain and can’t access why you’d be jealous, whay I can’t get is posting shite about them due to it.

Binus · 06/05/2026 08:12

icecreamflowers · 06/05/2026 00:13

So sorry, unable to find the 100 figure article. Found an article, see post above, that states 110 known of.

Thanks for providing a source.

It refers to allegations that have not been proven in court. So again, you don't know that 100 people have permanent blindness as a result of trusting this drug. The newspaper appears to be accurately describing the stage the proceedings are at, but it isn't any more than that.

ChunkyMonkey36 · 06/05/2026 09:33

Tattletale26 · 06/05/2026 07:05

This. They're furious that fatties have found a true solution that genuinely works, and desperate for the other shoe to drop.

It's quite satisfying actually watching their bitchy hatefulness thwarted:)

I lost nearly three stone on mounjaro, it was dead easy with the jabs and it's stayed off for a year, using maintenance shots.

The day after I started taking it, I immediately felt no nausea, inflammation went down, had far more energy than usual and food noise - which is VERY MUCH a real thing - vanished.

Zero negative side effects 18 months on.

Fabulous outcome and very satisfying watching them wail and gnash their teeth 😁

Nobody gives enough of a shit about individual fatties losing weight to “wail” about it.

You would have to have truly nothing going on in your life to be “furious” or “hateful” about someone else losing a couple of stone. Very dramatic response to someone else’s body.

Your weight loss might be the centre of your universe, but it’s not the centre of anyone else’s. Nobody’s bothered. It was your fat body and now it’s your thin body.

I’ve lost a stone in 6 weeks (so far!) - though apparently not through a “true solution that works,” despite it currently working.

I am nowhere near arrogant enough to think that you, or anyone else cares about that information, but I’m not doing it to get an emotional reaction from strangers, I’m doing it for myself. I don’t need a group round of applause, and I’m not interested how “furious” a woman on the internet is about my body decreasing in size.

In fact, if I don’t take to the internet to repeatedly proclaim my own wonderful work, the strangers on here won’t even know that weight loss has happened to form an opinion on it. Weird, eh!

Backawayfromthesausage · 06/05/2026 09:39

ChunkyMonkey36 · 06/05/2026 09:33

Nobody gives enough of a shit about individual fatties losing weight to “wail” about it.

You would have to have truly nothing going on in your life to be “furious” or “hateful” about someone else losing a couple of stone. Very dramatic response to someone else’s body.

Your weight loss might be the centre of your universe, but it’s not the centre of anyone else’s. Nobody’s bothered. It was your fat body and now it’s your thin body.

I’ve lost a stone in 6 weeks (so far!) - though apparently not through a “true solution that works,” despite it currently working.

I am nowhere near arrogant enough to think that you, or anyone else cares about that information, but I’m not doing it to get an emotional reaction from strangers, I’m doing it for myself. I don’t need a group round of applause, and I’m not interested how “furious” a woman on the internet is about my body decreasing in size.

In fact, if I don’t take to the internet to repeatedly proclaim my own wonderful work, the strangers on here won’t even know that weight loss has happened to form an opinion on it. Weird, eh!

Well they clearly do. I know you’ve read the thread, there’s been a shit ton of wailing and teeth gnashing, Christ some of it has been horrific,

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