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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To think it will be revealed WLI cause physical aging

830 replies

Tuliptana · 02/03/2026 07:14

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

OP posts:
Thread gallery
18
Unpaidviewer · 02/03/2026 09:06

Such a silly OP. Most people aren't using WLI to get to seriously underweight levels. WLI aren't causing ageing, the fat behind the skin makes it appear plumper. Most people using WLI will be far healthier after dropping the weight, is that not more important? And IMO most people look better and are more confident after weight loss.

Maia77 · 02/03/2026 09:08

I think it happens when you lose a lot of fat too quickly.

DarkForces · 02/03/2026 09:09

Imdunfer · 02/03/2026 09:05

Have you criticise with no idea what support a GP has to give someone on GLPs? From what I've read, it's a lot. Has your pharmacist sent you to a dietician? (I have no experience of it, just what I've read)

Do you know how long the waiting list is and how ill you have to be to get wlis on the nhs? I do. I also can compare my experience of getting long term medication on the NHS which has potentially dangerous side effects with that of getting prescriptions for wlis privately. It's far more thorough, but I appreciate that spoils your narrative that wlis are the Wild West of prescribing.

Imdunfer · 02/03/2026 09:09

Binus · 02/03/2026 09:03

Basically this.

It's also quite touchingly naive of that poster to think the NHS is going to do a better job at monitoring than the private prescribers are currently offering.

Can somebody tell us what support they are getting from an online pharmacy, who knows where in the world, where they got their GLP by taking a picture of the scales with them stood on them holding the dog? I'd be really interested to know.

BIossomtoes · 02/03/2026 09:10

Fearlesssloth · 02/03/2026 08:23

OMG I just googled Kelly Osborne (haven’t seen a picture of her in about 15 years). She is absolutely unrecognisable! She looks like a frail, elderly anorexic lady

She was so pretty before she did this to herself. It’s really sad.

DarkForces · 02/03/2026 09:11

Imdunfer · 02/03/2026 09:09

Can somebody tell us what support they are getting from an online pharmacy, who knows where in the world, where they got their GLP by taking a picture of the scales with them stood on them holding the dog? I'd be really interested to know.

Edited

What on earth are you talking about? I have live weigh ins, consultations with a pharmacist and regular advice and support. Not sure where my dog comes into it but she could do with losing a couple of pounds.

Imdunfer · 02/03/2026 09:12

DarkForces · 02/03/2026 09:09

Do you know how long the waiting list is and how ill you have to be to get wlis on the nhs? I do. I also can compare my experience of getting long term medication on the NHS which has potentially dangerous side effects with that of getting prescriptions for wlis privately. It's far more thorough, but I appreciate that spoils your narrative that wlis are the Wild West of prescribing.

Why are you reacting as if I'm criticising you going private? I'm in no position to throw stones at that glasshouse!

I'm criticising you criticising the NHS GLP progress with no knowledge of it.

AmythestBangle · 02/03/2026 09:13

@blossomtoes I wouldn't say she "did it to herself", which is judgemental and implies blame. She has mental health struggles. Which no-one chooses to have.

Calliopespa · 02/03/2026 09:13

EatMoreChocolate44 · 02/03/2026 07:20

Any extreme weight loss will age your face, that's why so many celebrities get fillers and have that 'pillow' look. Ozempic face is a thing apparently. Personally I think as you get older people look better with a little bit of weight on but everyone is different.

Personally I think as you get older people look better with a little bit of weight on but everyone is different.

I agree with this - and I believe there is also quite a bit of evidence that, as well as looking better, it is in fact healthier to fall in the overweight (though not obese) category after a certain age.

But you will get hounded to death on here OP for criticising WLI weight loss: lots of posters get properly wound up if anyone so much as raises a question about them.

HeidiLite · 02/03/2026 09:14

BerryTwister · 02/03/2026 09:06

@PurpleCoo if you are looking lean and defined, then you need to stop the WLI, if you haven’t already.

why? Those drugs are also legitimately prescrived for maintenance.
I'm not stopping my thyroid medication just because my levels are now fine.

Imdunfer · 02/03/2026 09:15

DarkForces · 02/03/2026 09:11

What on earth are you talking about? I have live weigh ins, consultations with a pharmacist and regular advice and support. Not sure where my dog comes into it but she could do with losing a couple of pounds.

Edited

You're incredibly defensive about taking a GLP, aren't you?

I'm talking about how other users of this forum have described obtaining GLPs from the multitude of less reputable online pharmacies.

DarkForces · 02/03/2026 09:15

Imdunfer · 02/03/2026 09:12

Why are you reacting as if I'm criticising you going private? I'm in no position to throw stones at that glasshouse!

I'm criticising you criticising the NHS GLP progress with no knowledge of it.

I do have knowledge that they don't have the capacity to provide support to everyone who is obese on the nhs. I work in the nhs and am very aware of the strain on it. They do not have the resources to provide the level of service I get privately. That's why they target it at the most at risk.

Survivingnotthriving24 · 02/03/2026 09:16

Kelly Osbourne has had a gastric sleeve and I think a fairly obvious buccal fat removal procedure, she claims to not have used injections so not sure it's a fair example. It's not the injections, its considerable weight loss that causes accelerated aging.

Notsosweetcaroline · 02/03/2026 09:16

Op factually and scientifically it is the opposite, there is now trials looking at the fact they are anti ageing.

so in real life they have found that the drugs are either slowing, stopping or reversing ageing in people. Inside, our organs.

from what I’ve read, as we grow up and then age, we get ill or we abuse our bodies, be it alcohol or fatty food etc, or we get viruses, and it damages our cells. This causes inflammation, and our cells carry that inflammation, the marker of the damage for ever, this is what ageing is and it is cumulative.

what they have found is the drugs reduce inflammation, and this reduction allows cells to regenerate, thus slowing, stopping or reversing ageing.

Kelly obsbournes face is really not the indicator here. But the scientific findings, and those are it’s the opposite.

the reason they need to now do trials to confirm the findings as if the findings are accurate and these drugs are anti ageing, then they have effectively found the fountain of youth and it can have a huge and much wider impact on us as humans.

MsGreying · 02/03/2026 09:17

One wli lady I know is moving into collagen drinks. I assume they feel old.
This one is dressing like their teen daughter and they're going out like twins. I can't imagine anything worse for the teen but I guess it makes you feel old and look old if you're comparing yourself to a teen

AmandaBrotzman · 02/03/2026 09:18

BerryTwister · 02/03/2026 09:06

@PurpleCoo if you are looking lean and defined, then you need to stop the WLI, if you haven’t already.

Why??
WLI are also used to maintain weight loss. Why should she stop using them and risk weight gain? Tell us you don't understand obesity and WLI without telling us...

Imdunfer · 02/03/2026 09:18

DarkForces · 02/03/2026 09:15

I do have knowledge that they don't have the capacity to provide support to everyone who is obese on the nhs. I work in the nhs and am very aware of the strain on it. They do not have the resources to provide the level of service I get privately. That's why they target it at the most at risk.

This discussion is like pulling teeth 😬. Yes, it's restricted because of the level of support they have to offer to anyone on it.

Could you just put it out of your head for a moment the notion that anyone is criticising your decision to go to a reputable supplier privately?

gostickyourheadinapig · 02/03/2026 09:19

Imdunfer · 02/03/2026 09:00

Pharmacies are part of the NHS?

If that were the case, the NHS would provide the premises and would be responsible for hiring-and paying-the staff.

BIossomtoes · 02/03/2026 09:19

There are a lot of extremely defensive pen users on this thread!

AmandaBrotzman · 02/03/2026 09:19

AmythestBangle · 02/03/2026 09:13

@blossomtoes I wouldn't say she "did it to herself", which is judgemental and implies blame. She has mental health struggles. Which no-one chooses to have.

Well she did choose to have the fat carved out of her cheeks at some point.

DarkForces · 02/03/2026 09:20

Notsosweetcaroline · 02/03/2026 09:16

Op factually and scientifically it is the opposite, there is now trials looking at the fact they are anti ageing.

so in real life they have found that the drugs are either slowing, stopping or reversing ageing in people. Inside, our organs.

from what I’ve read, as we grow up and then age, we get ill or we abuse our bodies, be it alcohol or fatty food etc, or we get viruses, and it damages our cells. This causes inflammation, and our cells carry that inflammation, the marker of the damage for ever, this is what ageing is and it is cumulative.

what they have found is the drugs reduce inflammation, and this reduction allows cells to regenerate, thus slowing, stopping or reversing ageing.

Kelly obsbournes face is really not the indicator here. But the scientific findings, and those are it’s the opposite.

the reason they need to now do trials to confirm the findings as if the findings are accurate and these drugs are anti ageing, then they have effectively found the fountain of youth and it can have a huge and much wider impact on us as humans.

I wonder how quickly the 'concern' about these amazing drugs will vanish then?

LaurieFairyCake · 02/03/2026 09:20

Total bollocks, my inflammation is now not discernible after being at goal weight on WLI’s for a year. Had a recent Thriva set of expensive blood tests that confirm I’m the healthiest in decades - not pre diabetic, all liver and kidney, thyroid functioning all improved.

before WLI’s I was having steroid injections in my knees, hips, one shoulder

I’m bloody decades younger now and can exercise when I couldn’t before.

ridiculous misinformation being spread about the injections.

Imdunfer · 02/03/2026 09:20

AmandaBrotzman · 02/03/2026 09:18

Why??
WLI are also used to maintain weight loss. Why should she stop using them and risk weight gain? Tell us you don't understand obesity and WLI without telling us...

At that point in time, the user needs to accept that they are entering a drug trial with entirely unknown long term consequences.

DarkForces · 02/03/2026 09:21

Imdunfer · 02/03/2026 09:20

At that point in time, the user needs to accept that they are entering a drug trial with entirely unknown long term consequences.

Okey cokey. Fine by me.

Binus · 02/03/2026 09:21

Imdunfer · 02/03/2026 09:09

Can somebody tell us what support they are getting from an online pharmacy, who knows where in the world, where they got their GLP by taking a picture of the scales with them stood on them holding the dog? I'd be really interested to know.

Edited

More than I've ever had from the NHS for the other medications I've had, but perhaps I ought to get a dog. For example, I took a medication that required me to submit blood pressure readings and the NHS was fine with me doing it myself at home, no checks. Nothing to stop me lying.

And sadly, I doubt the NHS would be able to offer all obese people the frequent consultation access I have with my private provider.