To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Why would I lie? I dont really care either way. I wouldnt take them myself, due to my scientific background, although I need to lose a couple of stone, am trying the gym, but my mother is a T2 diabetic and I have obese family members whose lives are severely curtailed by their weight so I think it is great they have been developed, for those people. I can't universally get behind them though when I hear people, who have no idea about how they work or the mechanism of action, talking about them like they're an illegal drug and competing to go from a size 10/12 to a size 6/8.

You can’t lump everyone together like that. I’ve lost a couple of stone, with one more to go on WLIs. It’s taken 9
months so far. I don’t want to lose any more than another stone because I’m in my late 50s and I don’t think being too thin would look good. I’m not in a rush, my aim is to be slim and healthy going into my 60s. I have no health conditions and all blood tests are fine, but I feel lighter, fitter and more confident. I wasn’t massively overweight but I feel better in every way and people have commented on it.

Yes, there are people on WLIs who are basically losing weight by starving themselves and it’s not good. But neither is any sort of extreme diet and that isn’t everyone. There are many people using them as an aid to weight loss and changing their lifestyle and eating habits. That’s a good thing and to suggest it’s doing damage to internal organs based on no evidence is just nonsense.

Couldn't agree more. 👏

While variations will exists, I find it unusual that someone would know so many people obtaining the drug deceptively.

It is notoriously difficult to guess someone’s weight, chubby can be obese. We see it on here all the time, overweight told they look slim, healthy weight models claimed as underweight, people have lost sight of what obesity looks like. It is chubby for most people.

and you’ve misinterpreted the info on the health benefits of being over weight as we age, it can protect against ailments such as osteoporosis but the dangers of it remain, they don’t go away as we are older, so needs to be offset by the risk of heart attack, stroke, diabetes, joint degradation, fatty liver, high blood pressure, high cholesterol etc.

im always surprised people seem to think as we age the risks go away, they do not. If anything they escalate, and it’s a personal decision if you wish to take all those risks to have the small benefit of potential osteoporosis protection, which isn’t even a given,

It wasn't osteoporosis I was referring to: it was studies on longevity, which are a pretty good proxy for overall health.

Oxford university disagrees with you.

https://www.ox.ac.uk/news/2009-03-18-moderate-obesity-takes-years-life-expectancy

And studies will be based on actual overweightness, not an approximation of a chubby person who actually happened to be obese because people had become used to seeing obese people.

@Notsosweetcaroline i’m still class 2 obese so I’m posting as a thick fat person 😆 I’ve jumped between 4 different pharmacies so far and while there’s info on their website (as there is across the internet) I’ve not spoken to a single human being yet and nobody has asked me about my dietary intake, exercise or anything like that, when I request my prescription. I do feel like that’s a gap that could/should be addressed by providers. As it is, I shop around to get the cheapest deal from a GPhC registered pharmacy.

Like you said, after years of trying to lose weight I consider myself pretty clued up on the science of weightloss (putting it into practice pre-WLI was the hard part). I am also very aware that a lot of the people taking the meds, sometimes from not legitimate sources, are not as chronically online as I am - are they getting the messages about eating enough food and maintaining lean muscle etc?

I am a WLI convert, but I do also think the method of delivery could be better and more holistic - might also mean we wouldn’t have to deal with as many snidey articles about how we’ll gain it all back as we’re all insatiable gluttons.

And what has that got to do with friable tissue and an anecdote from a plastic surgeon (who have a vested interest in getting people under the knife rather than taking weight loss injections if they were part of the American system)? Are you seriously suggesting I'm more at risk undergoing surgery at a healthy weight than when I was obese? People have been on these drugs for decades now and I'd think there would be a clear correlation by now.

Personal responsibility is a thing, I understand fully as no one is personally coaching you you feel it’s a Wild West, so why don’t you buy from a pharmacy that offers that, many do, would you like some recommendations?

I don’t feel I need this, I am educated and personally responsible so I chose a pharmacy that doesn’t wish to do consultations.

you can’t pick one which doesn’t offer it then whinge you want it. Buy from one who does offer it. As said, we can provide recommendations for ones where you do regular check ins and consultations.

Longevity alone or longevity of health. Two different things which sometimes overlap.

As a nation we have decades of illhealth ahead of us because although we live longer than we used to, that is not in good health.

As I said, I don’t feel I do need it right now - I’ve done years of various bootcamps and coaching to give me the basics. I’ve just been surprised at the lack of oversight so far. My comment was in the context of the wider theme of this thread, whether there are sufficient support and safeguards for those who might need it and are there likely to be longer term consequences to health if there aren’t? Maybe those will all be cancelled out by the benefits of weightloss 🤷‍♀️

I get what you’re saying too. I think there should be far more accountability in the market. The market seems to be responding to the non-obese people wanting the drug to lose weight when they are already a healthy BMI but they want to get skinnier by asking for photos in real time. It is scandalous how easy you can get these drugs without any personal contact. But, it’s a private free market. I’m a fellow fattie who like you did loads of research and am well educated and connected so I’m actually getting support from professionals who happen to be close friends. And Mumsnet groups are supporting me. And, to be blinking honest, Mumsnet support got me through years of infertility, IVF and raising my twins on my own and were far more helpful than 95% I encountered on my “journey”. Never under-estimate the power of the sisterhood or enlightened women, please.

If you feel you need extra support there's a list of pharmacies that provide it at https://monj.co.uk/mounjaro-support-help-providers/ .

I found the plastic surgeon article, it as in glamour magazine. It was specifically talking about face lifts and reduction in facial fat and muscle causing more sagging and harder surgeries. Totally anecdotal and I couldn’t see any studies or science to back it up, just the opinions of plastic surgeons. However it looks like there could be some truth to the assertion but it’s more to do with muscle loss, which could be seen potentially in other forms of extreme weight loss. Who knows? Until it is studied properly it is hard to gauge

I don’t - I was commenting on the fact others might but that it’s not a standardised offer, and maybe it should be.

I'd rather have the option of buying it as an additional service as it would just push the price up for a service I don't need (and you say you don't either). My provider has live updates, nutrition information, free access to Nutrable, a support forum and a website. I can book in with a pharmacist for £5. I really don't see what else would help.

Ffs

I also don’t feel it should be standard as it has a cost, I genuinely don’t need it, I’m fully aware and knowledgeable on what to eat, what a healthy diet is, and what work outs are required. I have no need to have check ins and consultations on my journey.

my understanding is most fat people have tried unsuccessfully to lose weight and keep it off for years before starting these jabs, and most know fully what to do, sure there is a small proportion who don’t, and the additional help is available to them if they require it.

plus as a pp said, the info is all over the internet anyway,

the problem is the societal perception of what is 'healthy' or 'overweight' is now totally skewed because most of the population is overweight. Someone you perceived as 'chubby' was very possibly obese, and definitely would be overweight. Even being slightly overweight is bad for your health (with the exception of frail older adults where it may be helpful)

Maybe read your link. And you will it shows zero evidence for the comment that was being challenged.

Zero.

Agree we really need to move away from subjective perceptions of chubbiness. They're no help at all. They certainly aren't a valid barometer of obesity.

Agree - someone up the thread talks about women with size 14/16 "mum bods" and how they were barely even overweight.

I had one of those size 14/16 bodies. And, being fairly tall at 5'8" , I probably carried it better than shorter people. Yet my starting weight when I was a size 16 was 17st 10lbs. My BMI was 37.7. That's not "barely even overweight" that's not far off morbidly obese. I was also obese at a size 14 and now, as a size 12, I'm technically still a few pounds overweight.

Even being slightly overweight is bad for your health (with the exception of frail older adults where it may be helpful)

Have a look at the Stanford studies on this.

It points to skewed methodologies that have tended to lump overweight and obese in the same category. In fact, they challenge the suggestion that overweight, especially at the lower end of a BMI overweight bracket, does have these impacts.