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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
Thread gallery
14
SilenceInside · 31/01/2026 13:48

That research is not new though, and preserving muscle whilst losing weight is a known issue, regardless of weight loss method. You are told to exercise if you are prescribed WLI, the information is out there and given to people. It is well discussed on the support threads. The majority of people are doing what they personally can to address that.

It’s not a reason not to lose weight or not use WLI.

HazelMember · 31/01/2026 13:52

Tumbleweed101 · 31/01/2026 08:57

I could probably benefit from using them for a while but I’m always a bit wary of new drugs, especially as
it is too soon for long term side affects to be known. Plus I couldn’t afford to pay for something like this long term. I don’t think I know anyone personally who takes them.

I think you are right to be cautious and cost is also a significant factor.

OP posts:
thetallfairy · 31/01/2026 14:00

I have been on them for 20 months

So far amazing

6 stone down

I am worried that some of my family members are flagging osteoarthritis 😬😬😬

HazelMember · 31/01/2026 14:06

thetallfairy · 31/01/2026 14:00

I have been on them for 20 months

So far amazing

6 stone down

I am worried that some of my family members are flagging osteoarthritis 😬😬😬

Well done on your weight loss!

As long as you are doing weight training, you will be fine. That will make up for any muscle or bone loss.

OP posts:
HereIGoOnceMore · 31/01/2026 14:21

thetallfairy · 31/01/2026 14:00

I have been on them for 20 months

So far amazing

6 stone down

I am worried that some of my family members are flagging osteoarthritis 😬😬😬

Lots of people have experienced a decrease in inflammation as an added benefit of taking GLPs and it is likely that arthritic conditions will be added to the co-morbidities that allow prescribing at a BMI of 27 in the near future. It will help people who struggle to exercise to lose weight whilst making it less painful to do so.

TheActualQueen · 31/01/2026 16:26

HazelMember · 31/01/2026 13:27

Muscle loss is a factor so can't be ignored.

https://news.liverpool.ac.uk/2025/01/02/weight-loss-drugs-help-with-fat-loss-but-they-cause-bone-and-muscle-loss-too/

A good weight training programme can offset any muscle loss of course.

Why would you not be exercising if you’re trying to lose weight?
Still wondering why you started this thread.

soupyspoon · 31/01/2026 16:37

SwingTheMonkey · 31/01/2026 12:01

I wonder if op is as concerned about the environmental impact of the first 4 in your list?

Wash your mouth out!!!

(actually dont, I think mouthwash might cause industrial waste)

soupyspoon · 31/01/2026 16:39

ACommonTreasuryForAll · 31/01/2026 12:01

I understand this isn't on everyone's radar or list of priorities, and while choice is limited, it is what it is; we have to accept medication in the form it is currently presented. But a switch to a more environmentally sustainable method of ingestion would be great: tablets or liquid in glass jars / bottles being a gold standard.
I quit using contact lenses because, as a parent, I couldn't justify the plastic waste, though. Ditto most other single use plastics.

I take it you didnt use disposable nappies, no one ever seems to talk about this.

RufustheFactuaIReindeer · 31/01/2026 16:43

Lots of people have experienced a decrease in inflammation as an added benefit of taking GLPs

absolutely, my hip doesn’t hurt when i sleep anymore, that change together with the better sleep happened within days of starting

Boomer55 · 31/01/2026 16:44

ladyamy · 30/01/2026 18:49

Self inflicted

When my late husband was alive, he lost a huge amount of weight. Medics told me to ram him full of dairy, fat , cream cakes,and sugar. He wouldn’t eat this crap unless I did. So, I did.

In the end, he gained zilch weight and I loaded it on. 🙄

He died, my appetite collapsed, has never really returned, and I’ve lost nearly 8 stone.

I put on weight when I was eating too much, and doing to little. . I lost it all when I wasn’t. 🤷‍♀️

HeidiLite · 31/01/2026 16:45

Boomer55 · 31/01/2026 16:44

When my late husband was alive, he lost a huge amount of weight. Medics told me to ram him full of dairy, fat , cream cakes,and sugar. He wouldn’t eat this crap unless I did. So, I did.

In the end, he gained zilch weight and I loaded it on. 🙄

He died, my appetite collapsed, has never really returned, and I’ve lost nearly 8 stone.

I put on weight when I was eating too much, and doing to little. . I lost it all when I wasn’t. 🤷‍♀️

well clearly you personally don't need the weight loss jabs then.

Binus · 31/01/2026 16:50

HereIGoOnceMore · 31/01/2026 14:21

Lots of people have experienced a decrease in inflammation as an added benefit of taking GLPs and it is likely that arthritic conditions will be added to the co-morbidities that allow prescribing at a BMI of 27 in the near future. It will help people who struggle to exercise to lose weight whilst making it less painful to do so.

It's so exciting isn't it! Really encouraging to hear about the potential benefits.

Alltheyellowbirds · 31/01/2026 16:52

Boomer55 · 31/01/2026 16:44

When my late husband was alive, he lost a huge amount of weight. Medics told me to ram him full of dairy, fat , cream cakes,and sugar. He wouldn’t eat this crap unless I did. So, I did.

In the end, he gained zilch weight and I loaded it on. 🙄

He died, my appetite collapsed, has never really returned, and I’ve lost nearly 8 stone.

I put on weight when I was eating too much, and doing to little. . I lost it all when I wasn’t. 🤷‍♀️

Im so sorry you lost your husband. I hope you’re doing ok.

ACommonTreasuryForAll · 31/01/2026 19:27

soupyspoon · 31/01/2026 16:39

I take it you didnt use disposable nappies, no one ever seems to talk about this.

No, cloth all the way, including for sanpro. I know, it's a conversation that should be normalised but people generally look at you as if you've got two heads.

soupyspoon · 31/01/2026 20:30

ACommonTreasuryForAll · 31/01/2026 19:27

No, cloth all the way, including for sanpro. I know, it's a conversation that should be normalised but people generally look at you as if you've got two heads.

Absolutely, people think its unthinkable.

velvetgeranium · 31/01/2026 21:58

godmum56 · 31/01/2026 13:19

I still wonder why people "want to debate" things they have no intention of becoming involved with and that affect them minimally if at all? btw, my Gina tablets come in non recyclable inserters and you will prise them from my cold dead fingers.

Perhaps you could pop onto the many Trump threads and ask them that. Or that long-running Salt Path series which I think are up to thread 20...

This is a discussion forum. You are in AIBU. People want to discuss what they find interesting. They want to discuss what they want to discuss, whether that's politics or towels or weighloss methods. There is nothing peculiar or inherently bitter in wanting to discuss WLI.

As a pp pointed out, you and others who are offended by discussion that may raise some negative potentials have the choice to hide the thread from actives as soon as you see it, or to hide it once you are on it.

godmum56 · 31/01/2026 22:05

velvetgeranium · 31/01/2026 21:58

Perhaps you could pop onto the many Trump threads and ask them that. Or that long-running Salt Path series which I think are up to thread 20...

This is a discussion forum. You are in AIBU. People want to discuss what they find interesting. They want to discuss what they want to discuss, whether that's politics or towels or weighloss methods. There is nothing peculiar or inherently bitter in wanting to discuss WLI.

As a pp pointed out, you and others who are offended by discussion that may raise some negative potentials have the choice to hide the thread from actives as soon as you see it, or to hide it once you are on it.

Edited

Well I think if things don't change soon, Trump is very likely to affect all of us, and I am guessing that the folk who are on the Salt Path thread actually watch the show?

velvetgeranium · 31/01/2026 22:17

godmum56 · 31/01/2026 22:05

Well I think if things don't change soon, Trump is very likely to affect all of us, and I am guessing that the folk who are on the Salt Path thread actually watch the show?

But none of these threads would appreciate someone going on them and saying why are you still talking about this, twenty-thousand posts later, in the case of the Salt Path upset threads. And yet every time anyone starts a thread outside of the WLI board, which has thousands of threads to discuss WLI experiences on, on come the usual suspects to try to shame and disparage and mock posters from discussing whatever aspects they are interested in discussing, or whatever new research that has come to their notice.

Why are people who are seemingly allergic to any discussion and not able to restrain themselves from reacting in this hostile way, in an attempt try to shut it down, not able to simply bypass it, the way the rest of us do when we find a subject triggering? I hide many threads immediately if the topic is upsetting to me.

Wickedlittledancer · 31/01/2026 22:22

velvetgeranium · 31/01/2026 22:17

But none of these threads would appreciate someone going on them and saying why are you still talking about this, twenty-thousand posts later, in the case of the Salt Path upset threads. And yet every time anyone starts a thread outside of the WLI board, which has thousands of threads to discuss WLI experiences on, on come the usual suspects to try to shame and disparage and mock posters from discussing whatever aspects they are interested in discussing, or whatever new research that has come to their notice.

Why are people who are seemingly allergic to any discussion and not able to restrain themselves from reacting in this hostile way, in an attempt try to shut it down, not able to simply bypass it, the way the rest of us do when we find a subject triggering? I hide many threads immediately if the topic is upsetting to me.

I understand you’re having an emotional reaction, but no one is doing what you are saying, they are either correcting misinformation, putting a wider context pointing out biases.

a discussion isn’t just an echo chamber where only those who agree can respond.

Binus · 31/01/2026 22:26

Equally, nobody on those threads would respond well to people who know absolutely bugger all wading in authoritatively. Which has happened on this thread and is a constant in WLI discussion. There's almost invariably people who have strong feelings with nothing back them up/beliefs that actually go against the evidence. If anything this thread probably contains less of that than the average lengthy WLI thread.

I don't know whether OP knows much about obesity in general. But if she does, she's chosen not to really display that in this thread. Most of her posts have been very short and not engaged with the more complex points. It's quite interesting either way.

velvetgeranium · 31/01/2026 22:32

Wickedlittledancer · 31/01/2026 22:22

I understand you’re having an emotional reaction, but no one is doing what you are saying, they are either correcting misinformation, putting a wider context pointing out biases.

a discussion isn’t just an echo chamber where only those who agree can respond.

Haha, there you go projecting again! I thought you weren't going to respond to me? And yet you keep doing it.

Correcting misinformation! What I see is a clutch of posters putting their fingers in their ears and going lalalalalala.

godmum56 · 31/01/2026 22:58

velvetgeranium · 31/01/2026 22:17

But none of these threads would appreciate someone going on them and saying why are you still talking about this, twenty-thousand posts later, in the case of the Salt Path upset threads. And yet every time anyone starts a thread outside of the WLI board, which has thousands of threads to discuss WLI experiences on, on come the usual suspects to try to shame and disparage and mock posters from discussing whatever aspects they are interested in discussing, or whatever new research that has come to their notice.

Why are people who are seemingly allergic to any discussion and not able to restrain themselves from reacting in this hostile way, in an attempt try to shut it down, not able to simply bypass it, the way the rest of us do when we find a subject triggering? I hide many threads immediately if the topic is upsetting to me.

Because those threads are started by people who have a vested interest in the subject. From what I can see, the OP doesn't want to take WLI which is fair enough, neither do I, but feels "uneasy" about it. I don't think I have shamed, mocked or disparaged, just wondered why the Op is bothered about something that they don't want to do themselves? I am not triggered about it, haven't tried to shut the thread down, don't feel any need to defend the choices of other people, neither do I care what they choose to do if it doesn't affect me. I mean I guess my question to the OP is "why do you care?" and if you don't care then why bother starting a thread?

Wickedlittledancer · 01/02/2026 06:58

godmum56 · 31/01/2026 22:58

Because those threads are started by people who have a vested interest in the subject. From what I can see, the OP doesn't want to take WLI which is fair enough, neither do I, but feels "uneasy" about it. I don't think I have shamed, mocked or disparaged, just wondered why the Op is bothered about something that they don't want to do themselves? I am not triggered about it, haven't tried to shut the thread down, don't feel any need to defend the choices of other people, neither do I care what they choose to do if it doesn't affect me. I mean I guess my question to the OP is "why do you care?" and if you don't care then why bother starting a thread?

Edited

My take is it’s people who spend a lot of time on line, read forums like this and think everyone is on them, when in fact it’s only about ten percent of the eligible population, 90 percent not on them, based on last stats of 2.5 million on.

as they think it is much more prolific than it is, they think they are getting left behind, the last fat person standing, that everyone else is on them and they can’t get them, or think fat people can now be effortlessly slim whilst they need to work at it. So they come on these forums and show their resentment or envy, if they can’t have them they don’t want anyone to have them, other than the extreme morbidly obese,

they aren’t understanding this is a health issue, or the wider benefits to society, or they do and they don’t care, for them it’s purely about appearance and weight for them. Their own versus other people’s.

ladyamy · 01/02/2026 07:40

Boomer55 · 31/01/2026 16:44

When my late husband was alive, he lost a huge amount of weight. Medics told me to ram him full of dairy, fat , cream cakes,and sugar. He wouldn’t eat this crap unless I did. So, I did.

In the end, he gained zilch weight and I loaded it on. 🙄

He died, my appetite collapsed, has never really returned, and I’ve lost nearly 8 stone.

I put on weight when I was eating too much, and doing to little. . I lost it all when I wasn’t. 🤷‍♀️

I’m so sorry to hear about your husband. Take care ❤️

HereIGoOnceMore · 01/02/2026 08:04

Don’t worry. I’m enjoying this thread - it’s fun to counter misinformation.