to feel uneasy about what this means long term rather than surprised by the weight regain itself?

[HazelMember]

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

I can understand why you want to wait and see.

More data will come out eventually.

No need to feel sorry for me.

A previous poster mentioned the environmental impact, so I had a quick look.

Yes it is true the insulin resistance/prediabetes can be reversed by diet and exercise.
However this is far far easier said than done!
Humans (in common with all other species) are hard-wired to eat as much food as they can get their hands on and not waste energy with unnecessary exertion!
Those who are prone to insulin resistance/pre-diabetes will be those who find it particularly challenging to resist these deep impulses.

The Wegovy pens can be recycled, the information for that is given out with the pens. The Mounjaro pens are not currently recycled and can be put in household waste. They don't need to go in sharps bins, the article seems a bit muddled about all of that, for some reason. I spend a lot of time reducing our household waste and recycling as much of it as possible above and beyond what is provided by our local council. I am happy that the impact of me personally using an injection pen a month is mitigated by that.

I also feel sorry for you, it’s clear you’ve an underlying issue that’s driving you and you don’t wish to reveal, I don’t think anyone believes you’re just really worried about people and the environment as you fail to balance your arguments, the insanity of all the links kinda underlines it.

its only you who is suffering, starting threads, googling anything negative etc, and I really hope you find peace with the fact the world has moved on, medical science has moved on and we have cured obesity as said, the biggest killer in society,

You’re only having “a quick look” when something negative is mentioned though aren’t you? You’re not listening to the many positives being mentioned in this thread and going off to find things to back those up.

You definitely didn’t start this thread with an open mind, or a desire to learn.

These threads always attract comments such as blood pressure or thyroid medication or asthma inhalers being for life and obesity medication is no different. BP isn’t always a “lifestyle” condition and thyroid problems and asthma aren’t so they are not comparable. My hypertension is genetic. My asthma is genetic. I do everything I can to help both conditions through lifestyle such as keeping a healthy weight, plenty of exercise, healthy diet and not smoking.
These threads are always the same with accusations that “skinny minnies” are just jealous. Jealous of what exactly? Reading threads where posters bemoan the loose skin and other negative consequences is unlikely to make anyone jealous. They are more likely to make people make sure they don’t get fat in the first place. Good for you if you are taking WLI and feel great and are healthier but there’s no need to criticise thinner people as you extol the glories of these medications.

AI also tells me that food production accounts for 25 - 30 % of global greenhouse gas emissions. How virtuous of people to eat less and reduce this impact.

Report the thread then.

No one is forcing you to participate.

Well said!!!!!

They start dragging out all other medications. How everything else should be considered the same!

a “lifestyle” condition

Ah, it's their own fault? In the subpopulation of individuals with obesity and severe obesity, genetic component accounts for about 60%-80%, according to Genetics of Obesity: What We Have Learned Over Decades of Research

That’s getting REALLY tired, you’ve said it to half a dozen people already.

It’s such a stupid and pointless response, not to mention unpleasant and passive aggressive.

Youre basically saying “if you don’t agree with me go away”. Why would you start a thread asking a question if you only want to hear from people who think the same as you?

Well done on your weight loss!

Hopefully people calculating the environmental impact of WLIs will ensure they factor in the other medications that are less likely to be needed with a less obese population.

I doubt the op is slim, although she may claim to be. Or as slim as she wishes. No one is criticising skinny Minnie’s, I’m one of them now. And no I don’t have lose skin, what an odd comment. Yes some get it, many don’t.

Loose skin is a negative consequence of having been obese, not of losing weight. You’d get it regardless of weight loss approach if you are prone to it. It’s not a reason to avoid losing weight or to avoid using WLI as much as it’s used as threat to obese people contemplating losing the weight.

What about how old and haggard we look though?!

I still wonder why people "want to debate" things they have no intention of becoming involved with and that affect them minimally if at all? btw, my Gina tablets come in non recyclable inserters and you will prise them from my cold dead fingers.

and how we have lost all muscle.

Muscle loss is a factor so can't be ignored.

https://news.liverpool.ac.uk/2025/01/02/weight-loss-drugs-help-with-fat-loss-but-they-cause-bone-and-muscle-loss-too/

A good weight training programme can offset any muscle loss of course.

Is it ignored though? It's discussed ad nauseum on WLI threads, either the support ones or the ones started elsewhere to "debate" them.

no way!

There is new research all the time that people may not have come across.

It’s off the charts isn’t it 😂

The injectors have their bingo card but there should be one for the predictable responses they put on these threads.