Meet the Other Phone. Only the apps you allow.

Meet the Other Phone.
Only the apps you allow.

Buy now

Please or to access all these features

AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

to feel uneasy about what this means long term rather than surprised by the weight regain itself?

682 replies

HazelMember · 28/01/2026 18:03

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

A woman, wearing bright red nail polish and unbuttoned blue jeans, injects herself into the skin and soft tissue of her lower abdomen with an obesity jab pen.

People coming off weight-loss injections risk fast weight gain

Overweight people shed large amounts on jabs but gain 0.8 kg a month on average once off them, study shows.

https://www.bbc.co.uk/news/articles/c050ljnrv2qo

OP posts:
Thread gallery
14
Ihateboris · 28/01/2026 18:27

Happygirl79 · 28/01/2026 18:24

You are absolutely spot on

Pharmaceutical companies are basically legal drug dealers. THEY WANT you to get addicted.

Gwenhwyfar · 28/01/2026 18:28

HazelMember · 28/01/2026 18:15

It would make sense for them to be more widely available as it would be cheaper for the NHS in the long run.

I would think that they will be more easily available on the NHS in future.

MO0N · 28/01/2026 18:28

Ihateboris · 28/01/2026 18:27

Pharmaceutical companies are basically legal drug dealers. THEY WANT you to get addicted.

Of course, they want a guaranteed income stream to protect profits & keep jobs.

SaintAgatha · 28/01/2026 18:31

HazelMember · 28/01/2026 18:22

Does this mean I have a problem with fatties being thin? To quote the language of the pp.

I think you’re being disingenuous. And you didn’t answer my question about statins.

Turmerictea · 28/01/2026 18:31

I took the tablet form for 3 months and lost two stone. Ive regained about 8lbs albeit very slowly. I thought Id go back on the pills and four days in, I got pancreatitis. So I can never take the meds again.

Back to faux keto and working out for me!

soupyspoon · 28/01/2026 18:35

CraftyMintHedgehog · 28/01/2026 18:22

I disagree.

This is a HUGE issue. It is a drug that needs to be taken continuously otherwise you lose all benefits. For those who might struggle with money, or have a change in financial circumstances, or the price of the drug goes up, then they have no choice but to stop.

But ultimately, people already know this so need to make sure they have the financial means to continue or accept that they will have to find a more sustainable way to lose weight.

The drug is made by Novo Nordisk, so what's to stop them suddenly pushing the price up? I mean, it would make them a LOT of money now all these people are so reliant on it. They have HUGE pricing power here.

This is how a lot of successful diet things work. Herbalife is the same - it's a starvation diet that is only sustainable if you keep paying the exorbitant prices for their shakes. As soon as you stop, the weight goes back on. And the people selling this stuff are making a HUGE amount of money from it, and throw huge party conferences to celebrate!

So YABU to accuse people of starting a bashing thread when this could become a huge headache for many people trying to lose weight.

Which is why it should be available on the NHS

This worry about unsustainable 'treatment' applies to lots of things that many of us have to purchase or source privately because the NHS doesnt supply it or wont do it in a timely way. See therapy as another example.

MagpiePi · 28/01/2026 18:40

Gingercar · 28/01/2026 18:15

I think it’s incredibly naive to think that you’re going to stroll off into the sunset without working very hard to maintain a weight loss. I’m on WLI and hope to drop them at the end. Most of my “naturally slim” friends work very hard at staying slim. I want to be like them - keeping an eye on my weight and reining myself in if need be. I definitely don’t want to stay on the drugs, despite having had no side effects whatsoever. I was obese, I’m not any longer. I was prediabetic, I’m not any more. I had high blood pressure and cholesterol, I don’t any more. I hope I can do it myself. I’ve been able to eat pretty normally on WLI l, I didn’t get full and had “food noise” so I hope I got used to using willpower and eating sensibly as much as the drugs.

You’d probably count me as ‘naturally thin’ but like your friends, it takes a lot of hard work to stay this way. From what I’ve heard other people say, I have all the food noise going on, but cope by having quite a restrictive and controlled diet and some pretty unhealthy attitudes to food, exercise and myself.
If they are now saying that people could stay on WLIs for life once they’d reached a healthy weight, why can’t people like me take them? I’d love to take a drug that stopped the constant battle that’s going on in my head.

Bruisername · 28/01/2026 18:42

I agree OP. I think they are great for tackling obesity but long term use of any drug should be avoided if at all possible and with obesity it’s important to tackle the underlying causes (societal I mean - as a pp said - pushing unhealthy foods alongside the WLI isn’t great!). Or even therapy if over eating is a trauma response.

of course the pharmaceutical companies have an incentive to keep people on them for life so why would anyone address the underlying causes of obesity

mindutopia · 28/01/2026 18:47

It’s shocking that this is shocking to anyone. There are no shortcuts to good health. It takes effort and discipline. I say this as someone who is overweight and enjoys food, but healthy food and exercise. It’s obvious this was always going to be the way things played out, but I think a lot of people are committed to believing it will be easier than it is (but it won’t).

Verytall · 28/01/2026 18:49

Many of the drugs are under patent, which is why they're so expensive. Once those patents expire it'll be possible for other manufacturers to make generic versions so it's likely there will be cheaper options available. That's why the big companies are trying to come out with new versions, so they can get the new patents and keep making money.

HazelMember · 28/01/2026 18:49

QuickBlueKoala · 28/01/2026 18:23

Weight loss only works if you change your lifestyle. Weightloss drugs are no different, so no surprises here?

Did I say there was any surprise?

OP posts:
ForeverScout · 28/01/2026 18:49

SaintAgatha · 28/01/2026 18:31

I think you’re being disingenuous. And you didn’t answer my question about statins.

I think it's a leap to say the OP is being disingenuous. I have similar thoughts about WLI, and that's coming from a place of living alongside someone on long-term SSRI meds. Should they not have taken them? Not at all - SSRIs saved their life. Are there serious implications and side effects of long term use, and significant issues weaning off them (should you not want to be on them the rest of your life) - yes. Ergo, SSRIs shouldn't be handed out like lollies whenever someone is feeling a bit sad.

I can be in support of medication treatment for serious depression while also being concerned at the potential for unintended long-term addiction (for lack of a better word, coming off can be a real bitch if not impossible, and no one tells you about that at the beginning) and the very real side effects, meaning my overall position is that both these issues should be weighed in the balance every single time a potentially long-term medication is prescribed. It doesn't mean people shouldn't use the "wonder drugs", more that the decisions made around them should not be taken as lightly as they seemingly are.

HazelMember · 28/01/2026 18:50

SaintAgatha · 28/01/2026 18:31

I think you’re being disingenuous. And you didn’t answer my question about statins.

Report me to MHNQ

Hide the thread

No one is forcing you to participate

OP posts:
Yellowsubmarine55 · 28/01/2026 18:51

If people doing anything diet wise be it slimming world, weight watchers or wli, if they don't change habits and return to eating rubbish in large quantities then gains will be expected. It's not isolated to wli.

It's a shame it's not available more on NHS but that's on its knees so not surprised. People who want to afford it will change spending priorities as it'll be important for their health.

As for side effects they're very rare, caused by what you eat and are treatable.

These articles are everywhere and are sensationalised aiming to panic people into believing there's no hope after losing weight so the only option is to stay on them.

nervouslywaitingagain · 28/01/2026 18:52

TempNameForObviousReasons · 28/01/2026 18:20

These WLI are going to come back and bite everyone on the backside in a few years.

Yeah, definitely being 24 stone, incredibly unfit and terrified of having a heart attack was a much better choice! I’ve lost 11 stone on MJ over 18 months. I’m now training for an ultra marathon, I’m bloody fit and I have completely and utterly transformed how I view food. Before it was something nice to stuff my face with, now it is fuel. What I eat and when I eat dictates how efficient my running is and how good my recovery is. I’ve been working back down the dosages (12.5 was my highest), mainly as when I was upping the distance running wise I was struggling to eat the required calorie intake to fuel it. If I can come off it then I of course would, but if I have to be on it for life then it is worth it for me. It’s absolutely transformed my life.

SalmonOnFinnCrisp · 28/01/2026 18:53

I'm on them and dont disagree.

The real solution is preventing obesity in the first place.

I'd like to see a lot more energy put into preventing childhood obesity / encouraging stable weights....
because ime if you are a fat child you are fat /struggling with fat for life.

LaurieFairyCake · 28/01/2026 18:55

There will be pills available for £20 a month in a couple of years

Gingercar · 28/01/2026 18:55

LookingThroughGlass · 28/01/2026 18:17

That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

They have the choice to maintain the eating habits they've adopted on WLI - it may be hard but no harder than starting a diet from a position of being obese.

This has always been my aim. I will have hopefully lost 5-6 stones while on WLI and I may have another stone to go when I come off them, or I may be at goal and have to maintain it. Either way, it will hopefully be a lot less daunting task than what it felt like with six or seven stones to lose..

HazelMember · 28/01/2026 18:55

Yellowsubmarine55 · 28/01/2026 18:51

If people doing anything diet wise be it slimming world, weight watchers or wli, if they don't change habits and return to eating rubbish in large quantities then gains will be expected. It's not isolated to wli.

It's a shame it's not available more on NHS but that's on its knees so not surprised. People who want to afford it will change spending priorities as it'll be important for their health.

As for side effects they're very rare, caused by what you eat and are treatable.

These articles are everywhere and are sensationalised aiming to panic people into believing there's no hope after losing weight so the only option is to stay on them.

If people doing anything diet wise be it slimming world, weight watchers or wli, if they don't change habits and return to eating rubbish in large quantities then gains will be expected. It's not isolated to wli.

Yes of course but the article says:

People who come off slimming jabs regain weight four times faster than dieters

OP posts:
soupyspoon · 28/01/2026 18:56

ForeverScout · 28/01/2026 18:49

I think it's a leap to say the OP is being disingenuous. I have similar thoughts about WLI, and that's coming from a place of living alongside someone on long-term SSRI meds. Should they not have taken them? Not at all - SSRIs saved their life. Are there serious implications and side effects of long term use, and significant issues weaning off them (should you not want to be on them the rest of your life) - yes. Ergo, SSRIs shouldn't be handed out like lollies whenever someone is feeling a bit sad.

I can be in support of medication treatment for serious depression while also being concerned at the potential for unintended long-term addiction (for lack of a better word, coming off can be a real bitch if not impossible, and no one tells you about that at the beginning) and the very real side effects, meaning my overall position is that both these issues should be weighed in the balance every single time a potentially long-term medication is prescribed. It doesn't mean people shouldn't use the "wonder drugs", more that the decisions made around them should not be taken as lightly as they seemingly are.

What about bipolar or schizophrenia (other psychoses)?

soupyspoon · 28/01/2026 18:57

Yellowsubmarine55 · 28/01/2026 18:51

If people doing anything diet wise be it slimming world, weight watchers or wli, if they don't change habits and return to eating rubbish in large quantities then gains will be expected. It's not isolated to wli.

It's a shame it's not available more on NHS but that's on its knees so not surprised. People who want to afford it will change spending priorities as it'll be important for their health.

As for side effects they're very rare, caused by what you eat and are treatable.

These articles are everywhere and are sensationalised aiming to panic people into believing there's no hope after losing weight so the only option is to stay on them.

Im of the opinion that the panic is led by food producers and manufacturers/supermarkets so that people think they wont bother losing weight at all and keep eating food they dont want or need, keeping profits high.

TwentyFourHoursToTulsa · 28/01/2026 18:57

People are already on them longterm. For diabetes. You want them to stop?

My DH is on medication for high blood pressure longterm. Should he stop?

LeafyMcLeafFace · 28/01/2026 18:58

Jackiepumpkinhead · 28/01/2026 18:05

Another WLI bashing thread, what fun. I’ll get my bingo card ready.

That’s the first one for the bingo card as soon as anyone mentions WLI

soupyspoon · 28/01/2026 19:00

HazelMember · 28/01/2026 18:55

If people doing anything diet wise be it slimming world, weight watchers or wli, if they don't change habits and return to eating rubbish in large quantities then gains will be expected. It's not isolated to wli.

Yes of course but the article says:

People who come off slimming jabs regain weight four times faster than dieters

What are the stats about the amounts, is it that they regain faster but regain evreything they lost, or more than they lost or less than they lost and how does that compare to SW and WW and Jane plan and keto and all the others?

HazelMember · 28/01/2026 19:01

soupyspoon · 28/01/2026 19:00

What are the stats about the amounts, is it that they regain faster but regain evreything they lost, or more than they lost or less than they lost and how does that compare to SW and WW and Jane plan and keto and all the others?

Don't know. You could try and look it up I guess.

OP posts: