This is certified bollocks.
Comments like these are misogynist and create a hostile environment for female employees.
In this instance the innuendo is clear - this man is suggesting that your lips (mouth) or more likely your genital lips will be inflamed by sexual activity.
I'd advise you to go back to HR using these terms:
"John Smith's comment suggested that during my time off my lips or, more likely, my genital labia would be inflamed in a manner which calls to mind sexual activity.
There is a history of similar comments by John Smith.
Severally and in combination, these comments create a hostile environment for female employees.
In failing to address this complaint, [Company Name] are choosing to allow this hostile environment to continue. "
As a general rule, raising a formal grievance about things like this will definitely change the culture, because organisations are very wary of having a paper trail like this.
Please, destroy these motherfuckers.