to think more negative effects will come out from Ozempic use?

[nameey]

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

Come on! Everyone feels upset it’s so hard to get face to face appointments with NHS doctors these days!

That doesn’t mean we want more appointments to move online it means we want more doctors.

Obviously in your case it was clear cut that it was worth prescribing a weight loss drug & that the benefits would almost certainly outweigh any potential risks. But what about all the people getting weight loss drugs via private pharmacies who aren’t obese? I would say it’s too easy to do that at the moment. And all the people saying they plan to stay on weight loss drugs for life on a maintenance dose…don’t they realise they won’t qualify for it anymore once their BMI is in the normal range or even the overweight range. Or do they intend to lie about their weight once they no longer qualify?

1- loosing weight when you’re overweight, let alone obese, isn’t a vanity issue. It’s a health issue. And if it was that easy ‘to just loose weight’ people wouldn’t be overweight or obese!!

2- all medications have risks. I’m sure you use ibuprofen? About 2000 people DIE each year from normal use of ibuprofen. Paracetamol? Many people develop liver issue from regular use (aka within recommended disable etc…)
And yet there are many other ways to deal with a headache tyat dint involve using painkiller. Starting by ridding it out. I hope that’s what you’re doing because otherwise, it’s just comfort right? Why put your life at risk fir a bit of comfort hey…

People who don’t feel there’s anything to debate will presumably leave this thread. No one is forcing you to read other peoples opinions or reply to them.

We all know all medications have side effects. Please actually read the posts you are responding to.

The question is, what are the chances that over time, new, unexpected, serious side effects could emerge?

Maybe a large number of people who take it gets dementia. Maybe longer-term use will be shown to lead to osteoporosis in a significant number.

Or something else which is serious enough to change the balance of harms when considering whether to take the drugs.

"Everything has side effects" is not an answer. A number of weight loss drugs over the years feel out of use due to side effects or other issues. Sometimes because users no longer consider the trade off reasonable. In other cases, it's because whatever the users think, the medical establishment decided that it wasn't appropriate - being addicted to speed for example isn't a good trade off for losing weight.

Some people seem keen to dismiss the idea that significant risks to medications and treatments can emerge later. If it's been tested they are sure it must be ok.

My post was essentially saying - this is a drug with a system wide effect on the body, that people will take for a long period of time - I think those are the kinds of drugs where serious side effects do sometimes unexpectedly emerge.

1- private pharmacies are bound by the same rules. I have a private prescription even though my BMI is well into the obese category. Why? The cardiologist that advised me to go down that route also said ‘it’s so hard to get it in the NHS. If you can, just go private’.
Its not because you go private that you dint really need it for health reasons.

2- the legislator decided that a BMI over 28 was enough to get the medication. Not people. Not pharmacists. But somehow, the health benefits were seen as good enough fir overweight rather than obese people too. If you have an issue with that, you need to take it to the legislator and doctors who took the decision

3- the really big issue isnt pharmacies or doctors etc… it’s all the other people like beauticians that provide that medication. It’s the fakes. Now THAT is an issue. Let’s concentrate on that.

From the NHS website Gastroparesis - NHS

It doesn't sound like anything anyone could test for prior to the jabs anyway.
Considering the long term damage of smoking, drinking and eating chemicals in our food I'm not sure it will put off people being on a 6 months weightloss jab.

Why wouldn’t they qualify? That’s the whole point of a maintenance dose. That you started obese, have got to a healthy weight but continue the medication for as long as you choose. You don’t get to a healthy weight and suddenly have to come off it. You may have trouble moving pharmacies but there’s no reason why you can’t stay on a maintenance dose, long after you’ve reached your goal weight.

And it’s not easy to obtain since rules were changed in January of this year.

@Twiglets1
You've just outed yourself as completely uninformed despite asserting yourself as being an expert on prescribing practices I'm afraid. It is perfectly possible and legal and within Nice regulations to continue to use WLIs once you reach a healthy BMI, long term, to maintain the health benefits.

@Twiglets1 you're incorrect about BMI and not being able to continue with the medication. The BMI requirements are to start, then obviously you need to continue to take the medication until you get to a healthy BMI. That's the intended use of the medication. Mounjaro can be taken on an ongoing basis for maintenance if needed. Many pharmacies offer this service and will continue to prescribe as long as you aren't losing weight to the point of going towards the underweight territory. Diabetics clearly can expect to stay on Mounjaro long term if it's working for them and they're not losing weight.

Nope, literally nobody has said there is no chance of side effects emerging at a later date, please read the posts.

Years ago I was on an antidepressant for a few years that was later found to potentially cause an enlarged heart in some users. I had to have reasonably regular echocardiograms - thankfully didn’t have any issues. Would it put me off starting a medication that could hugely benefit me because at some point in the future a serious side effect could be linked to it? Absolutely not. Same with this drug.

So in 2023 there were an estimated 20 million people on this drug so 18 cases of ileus is a concern however incredibly rare and not enough to warrant removal of the drug. It is a less than a 1 in a million chance.

So back to my previous stament the fda and mrha here constantly over see this data and if a concern is high enough they freeze or withdraw a drug.

The other gi issues were identified at clinical trial.

Yes exceedingly rare side effects may emerge but the 1 in a million chance does not outright the positives of the drug.

Do you mean losing weight?

(a) pharmacists can prescribe off label. That doesn’t mean it’s not legitimate
(b) Wegovy is the exact same drug as ozempic and is the weight loss branded version

You know you’ve lost the argument when that’s all you’ve got left. I’m actually cringing for you. Just as well it’s anonymous eh?😳

I am not disappointed by you or what you say 😂

Carry on with the drugs, I don't care either way. It is not that deep 😂

Anyone is free to start a thread, Just because you don't like it doesn't mean it is daft or mad. Why not just be happy with your drugs and stay away from the thread?

If you are so happy with the drugs then why is there the need to keep saying how happy you are and showing so much defensiveness and making accusations? Maybe it is time for you to do some deeper inner work.

The people are keep banging on about being happy are usually the unhappy ones.

Have a great weekend!

The osteoporosis is a lot more likely to have come from her long-term eating disorder.

Why are people so Ill informed posting, what’s actually possessing you. Are you not embarassed by yourself? I’m embarassed for you and I don’t even know you. I’d be sitting cringing myself inside out if I was posting shite like this.

mounjaro is approved for life time use. You can stay on a maintenance dose of your choosing, as long as your body weight doesn’t go into the underweight category. It also doesn’t wear off.

i will stay on, my gp is supportive of this, even though it is private prescription.

i aM also fortunate I can afford to do so. Others will come off and go it alone. But we have the choice.

you may now need to go lay down and hyperventilate. Not only can we get slim, we can stay that way !

Well I feel it’s important to challenge people posting shite. Wanting me to not challenge you and stay away isn’t going to happen.

if I wasn’t happy on the drugs I’d not take them, try to think logically will you. No private pharmacy is knocking on my door, demanding money and holding me money and injecting me. Why would anyone take them and not be happy to do so.

it does seem to really piss you off people are so happy. Now I’m secretly unhappy and need deeper work. Yeah ok. I will do that when I shimmy into my size ten jeans.

😂

So you let the lost weight loose then.

What do you mean?

The correct use of the words loose and lose.

Losing something is causing its loss.
Loosing something is causing it to become loose.

Maybe side-effects will come to light in future, but probably not given it has already been in trials for years. I think massively reducing people's chances of cardiovascular disease and diabetes is worth it.

Mounjaro is a strange one, in that I don't think there has ever been a prescription drug treated quite so much like a fun consumer product (chummy forums, mango emoji, tweaking how you use it). Which gets a few backs up in people who don't use it.

In an ideal world I'd like to see more tailored dosing than the guidelines of 2.5mg, 5mg etc. There are a few people on too high a dose and not able to eat properly, nauseous etc for days on end and think that is normal for the drug. That, I would have thought, would be more likely to lead to long-term side-effects than taking a more specific tailored dose.

But while the NHS can't roll it out widely (and don't have GP time to spare on closely helping people), and most private prescribers see it as a one size fits all consumer product, people are possibly left to their own devices and forums a bit too much.

How about 'loser'. Did I spell that correctly? I'm sure you are very familiar with the word.