To think all these weight loss jabs are a bad move?

[Pineconecollector]

I’ve seen so many people recently saying they’re on Mounjaro - someone wrote on Facebook that they were struggling to eat anything at all, hadn't eaten for over 48 hours. Just zero desire to eat anything. Surely that can’t be healthy?

I also know of someone who has lied to an only e pharmacy to get the jab, because her BMI would be considered too low to be prescribed it. She’s wanting to get down to a size 6.

True, but many of those conditions can’t be changed by lifestyle alone and require medical intervention.

To be clear, I think morbid obesity is a disease impacted by genetics. The difference is some
people who might not be in that category are still queuing up to acquire the medication - which like everything does has side effects.

Subcutaneous injections are not invasive

I hadn’t realised you were a geneticist. Have you any peer reviewed papers I can have a look at to support your views?

You show me yours and I’ll show you mine. 20 years in biotech.

@InductionHobRocks this medication is for those who are obese, as well as the sub category who are morbidly obese. People who are morbidly obese have a more pressing need to lose weight, so the risk/benefit analysis is obvious. But being "just" obese still comes with long term risks and poorer health outcomes. So the benefit of these injections to lose weight is still worth the risks. That's the whole point of the analysis of the research, by the MHRA to decide who to approve this medication for. But for some reason, people with very little accurate information on these injections seem to be totally confident to disagree with the MHRA and all the other relevant bodies that have looked at these medicines and approved them.

Again, it's simply not true that eat less move more (ie lifestyle change) works. The failure rate for this type of advice to drive weight loss is enormous. Obese people have heard and understood the message but it hasn't worked for them.

The drugs are not aimed at people who want to drop a few pounds. They are aimed at those whose health is impacted by or likely to be impacted by their weight.

Many drugs are open to abuse but we don't withold them from those who need them just in case they are used by those who don't.

My sister in law died. She was on weight loss injections for around 18 months or so. - developed pancreatic cancer, lasted 6 months after diagnosis. Is it related, who knows?

I don't know what the answer is, but I do know it's a measure of desperation that so many people sign up to it.

Good luck everyone, I wish you well in your weight loss journey whichever road you choose.

Did you read my post or just post a response with no reference to it?

Where did I say eat less move more?

You said lifestyle change. Obese people have usually tried very many changes to their lifestyles. What advice would you give that you think would turn back the increase in obesity?

Right. How does that make you able to confidently claim that morbid obesity is impacted by genetics? What if someone has a bmi of 39? Just a greedy fat bastard, unable to stop eating cake?

I tried Mounjaro for two months ….the constipation I experienced was off the scale, I came off them and went onto the NHS diabetes remission programme instead…meal replacements for 12 weeks followed by a phased reintroduction of food….im now on the final phase and I’ve been under the care of a dietician the whole time.

Thes GLP1 drugs are absolutely amazing for many people but didn’t suit me….I'm in remission from diabetes thanks to the meal replacement plan and close support, but will always have to watch my weight.

Your post came across as flippant; it was also totally ignorant and extremely rude to those of us, including some GP and other medical professionals, who're taking this life changing, licensed and prescribed weightloss injection. It deserved the lite response and more.

If we're "hangry", at least it means we're eating less calories like you want us to, doesn't it? We're not still stuffing our faces while doing the jab, like some posters have said about the WLI. It's a win.

Precisely
And if they eat a few extra cakes and hit the magic 40 morbid obesity category, BOOM! Our 'geneticist' and no doubt also 'endocrinologist' @InductionHobRocks deems them worthy of treatment

Laughable

I believe they are angry that we are NOT stuffing our faces, actually.
They want us to be obese and suffer all the associated comorbidities
That's the only explanation here, frankly

( Sounds like you are a fellow doctor!)

I couldn’t care less how many calories you eat
I simply stated it doesn’t teach good eating or exercise habits. Which is true. And it’s touched a nerve with people - which has everything to do with how they feel about themselves and nothing to do with me.

If you lose weight on tablets or jabs - good for you. But presumably you’ll be off them one day and unless you make the effort to eat better and exercise you ain’t keeping that weight down

That’s a very weird take and a massive projection “Dr”

I’ve been told on this thread I want people to be fat, I’ve also been told I want them to be thin.

I think you all need to find a way to be less grumpy and snappy TBH

Of course you don't care. It was obvious from your first post. Anyway, you sound ridiculous so I'll let you plop on and go. I'm not about to repeat facts that are all over this thread if you weren't too lost in your own half-baked preaching to care to do basic reading.

"It doesn't teach good eating or exercise habits" - Wow! Mindblown! Who woulda thunk that? Thanks for that valuable tidbit and the rest of your post - it's a new lesson for us fatties for sure.

I think it's utterly reasonable to be tetchy about people thinking that it's earth shatteringly novel to tell obese people to eat less and move more, and that unless they do things differently the weight will be regained. I mean, no shit. Do you genuinely think that people who are obese and using weight loss injections aren't aware of that? Why do you think it's vital to "inform" people of this?

You'll find the jabbers are not at all grumpy. The opposite, we are delighted with a treatment and are enjoying regaining our health.

We are rightly irritated by those who don't take the medication, haven't taken the time to understand them, yet feel they are somehow a 'bad move'

The medical community is citing them as a miracle drug. Read last month's BMJ, which had a lot of discussion about it.

Or that original study on NEJM in 2022

These are fantastic drugs, happy jabbing everyone!

I think you all need to find a way to be less grumpy and snappy TBH

Tell us what you recommend since you're here doing the preaching. Should we eat more, eat less, do more exercise, do less exercise? What should we do that wouldn't gather any criticism from those obviously better and wiser than us?

That is true of every weight loss method, including behavioural interventions to teach better diet and exercise behaviours (see list to BMJ article below). Not why you think this works as a unique objection to weight loss injections? The comparator is also failure to maintain, and not success.

What are you even taking about?

What’s laughable is you literally making up responses to comments people haven’t made because you’re in a frenzy.

Are you so unaware there ARE genes associated with obesity in the same way there are with breast cancer. If genome sequencing was used as a diagnostic we’d be having some very different conversations.

WHERE did I say anything about only people with a BMI of 40? i didn’t. More absolute nonsense.