You are now discussing pseudo science I suspect. Science cannot 'transcend' the physical to ever make a male person a woman or vice versa. No matter how you wish it could happen in the future, unless a device is invented to turn back time and totally recreate a body from the atom level and change every cell in that body.
A male person has experienced life as a male person from the moment they were born and this shapes their life. In fact, it could be said that female people in some societies are still negatively discriminated against from conception. I doubt you can say the same about male people.
No person is born in the wrong body. No person claiming to be a woman but is male has any true concept of what being a 'woman' is. It is only their interpretation of womanhood.
If you cannot see this, then you will be disappointed if you hold onto the physical science will be transcended in any way to make what you wish to be true, true.