Good health - none of us really have much control over this. Main ones for me are disability due to a car accident where I was stationery and mh issues which are a mix (the experts think) of genetics, physiology, brain chemistry and trauma - no cure available for either
Another saying another child (there's a lot of us eh!) - lost 3 before dd to mc, dd was a tricky pregnancy and birth and revealed that to have another pregnancy due to a rare medical condition would likely have killed me. I wanted a big family but it wasn't to be. It's been hard to come to terms with esp as ex has a large family with wife 2 (6 kids)
My heart goes out to those in similar circumstances and of course even more so to those who've been unable to become parents when they wanted to and those who've lost children 
I'll admit I'm smiling a little at the non singers, I've sung all my life and honestly at one point thought everybody could at least carry a tune...then I met a lovely friend who is amazing in many ways but has a voice that could cause physical pain! She's fantastic! But seriously if someone ever held a gun to her head to make her sing they'd regret it!
Men who whisk you off your feet and generally into big romantic gestures are often narcissists - it’s about them not you -and not good partner material.
Have to say I agree with this
Heart also goes out to all of you that have had difficult family relationships, inc of course abuse and to all those who've experienced trauma