Will you be getting the COVID-19 vaccine?

[sloganhan]

It’s looking like this vaccine will be here sooner rather than later. I’m not sure how I feel about it to be honest.

Will you be getting the vaccine?
YABU - YES
YANBU - NO

@Rebelwithallthecause That's why they're doing the trials. If transverse myelitis does show as a very rare but possible side-effect, that vaccine won't go into production.

This is a response from a Dr to the recent BMJ paper on the pausing of the oxford vaccine trial and it doesn’t fill me with confidence...

Dear Editor,

Biologic Products can lead to a vast array of Adverse Effects; many of them manifest late. Subacute Sclerosing Pan Encephalitis (SSPE) can develop 1 to 30 years after exposure to a Virus or a Vaccine; the average time before SSPE Manifests is about 7 years from such exposure. So, certainly however large the Trial Group is, such late manifesting Adverse Effects will not surface in the short time that the Fast Track Trials are trying to prove the Safety of the Vaccines.

It should not become a case of a Cure worse than the Disease.

Arvind Joshi; MBBS, MD; FCGP, FAMS, FICP;

@Gancanny

Vaccine development usually goes roughly like this:

Research team wants to look in X Disease > applies for go ahead to start research > wait > approval given > applies for funding for research > wait > funding awarded > research starts > research is promising > reports findings > wait > findings reviewed > wait > reviewed support initial findings > apply for permission to proceed to next step > wait > permission granted > apply for funding to proceed to next step > wait

And so on and so on.

Many of the steps in research and development involve applying for funding and waiting for approval.

The covid vaccine wasn't starting from zero, there have been several ongoing studies into a coronavirus vaccine for years and the research into those was able to be carried across. They have been given all of the funding they need and the funding is there when they need it with no delays due to "apply and wait", and they are able to run stages concurrently rather than consecutively. None of the stages are being missed out and none of the safety protocols have been cancelled or suspended.

This new vaccine is an example of how quickly medicine can advance when given proper funding.

Your correct. There have been ongoing Covid vaccine research for at least 20 years specifically since the SARS outbreak. I suggest you look at what happened to the animals they tested the vaccine on when they reintroduced the virus to vaccinated animals. It failed. Gravely. Now we have skipped the animal trials and gone full in to human trials.

92% of people will not need this vaccination.

I would, I've volunteered for the trials. The email o got recently says testing is going to go on until mid next year so it could be a year before it's even ready.

This isn't going to go away any time soon.

Now we have skipped the animal trials and gone full in to human trials.

No, we have not. That's just not true. Why do you think this is true?

Now we have skipped the animal trials and gone full in to human trials.

The Imperial and the Oxford trials both used animal testing in the early stages of their development.

I'll give it a couple of years to see what it does to others first, then I might consider it.

Yes

100%.

I want the pandemic to be over and I really want to be able to come to England and visit my parents.

@Gancanny

Now we have skipped the animal trials and gone full in to human trials.

The Imperial and the Oxford trials both used animal testing in the early stages of their development.

Moderna was doing animal trials in May:

www.nature.com/articles/d41586-020-01092-3

Yes definitely, although it will be a while until I’m offered it. I’m vulnerable but not on the priority list. If you don’t want to get it great, more for the rest of us who want it and will be able to travel etc. once we have it. Will be a long, boring life for those that don’t want it as looks like there will be vaccine passports as there as for some other diseases.

Lots of information on SARS-CoV-2 vaccines in this twitter thread by a Professor at the Department of Microbiology Icahn School of Medicine at Mount Sinai:

mobile.twitter.com/florian_krammer/status/1310372301314101250

Absolutely!

@GoldenOmber

Now we have skipped the animal trials and gone full in to human trials.

No, we have not. That's just not true. Why do you think this is true?

They have been trying this on animals for over 20 years with no result they are already trialing it in humans. Your telling me that in the space of six months they perfected the animal trials and were able to move on to humans?

The Oxford trial also states vaccinated ferrets shown mild resistance to the virus. When did mild resistance become good enough?

The skipped the animals to get the big money pay out. Who ever wins this race will make hundreds of billions.

The independent board, Fauci said, could decide "the data is so good right now that you can say it's safe and effective." If the clinical trials were to produce results that are overwhelmingly positive, scientists would have a "moral obligation" to stop the trial early and make the vaccine available to all participants in the study, speeding up the process to make it more widely available

They are rushing it.

I will eventually, but I'm young and healthy (and fought it off fine when I had it in April) so I would make sure I waited until those who really needed it were able to get it.

I’m late 50s, white female, of healthy weight, no underlying conditions, on HRT and VitD. I’m willing to take one for the team and have signed up for the trial. I’m not worried about speed of development or anything like that because I don’t believe corners have been cut.
However, I don’t believe a vaccine is imminent, despite what I heard in a meeting earlier this week, and if I’m honest I don’t believe there ever will be a vaccine.
I’m having my flu jab this weekend and taking sensible precautions against Covid.

Personally I don’t want the younger generations to volunteer to take it unless they are done with having children.

No, just like I don't (and wont) get the flu vaccine.

They have been trying this on animals for over 20 years with no result they are already trialing it in humans. Your telling me that in the space of six months they perfected the animal trials and were able to move on to humans?

You're talking about different vaccines. There is not one single vaccine they've been banging away at for 20 years. And there is not one singular 'they' developing vaccines, there are multiple different teams developing multiple different approaches, who are doing animal trials as part of standard vaccine development. Plus in at least one vaccine (possibly all but I don't know), extra animal trials to check specifically for ADE, which is the problem I think you're referring to in the original SARS-1 vaccine attempts.

You do not know what you are talking about here. Please stop scaring people, and yourself, by cobbling together random things you have heard from different places and declaring the bad scientists are going to kill us all.

I'm a doctor. I have had many of my colleagues become severely unwell, some go to intensive care, and very sadly some died. Many were young and fit. All working age, obviously. We saw the young and the old admitted due to coronavirus.

I highly recommend uptake of the vaccine. Initial stock will be for those at higher risk, but it will be eventually rolled out. It's important that those who can receive it, to provide herd immunity, and protect the minority who will not be able to be vaccinated due to a medical reason

@blueberrypie0112

Personally I don’t want the younger generations to volunteer to take it unless they are done with having children.

Could you expand on why this is? I still hope to have children and I’m ECV so need the vaccine. Is there evidence it’s harmful to fertility? If so please can you direct me to the research?

More like they become pregnant and didn’t know if and this vaccines didn’t work out well.

@Cabinfever10

Yes I really want it so much so that I've signed up to be a test subject. I'm just hoping that the need me🤞

Same here.

@blueberrypie0112

More like they become pregnant and didn’t know if and this vaccines didn’t work out well.

Is this something you personally think or have you evidence for it? It’s quite worrying if true...and I need you to provide evidence for what you are saying and if it is true.

@GoldenOmber

They have been trying this on animals for over 20 years with no result they are already trialing it in humans. Your telling me that in the space of six months they perfected the animal trials and were able to move on to humans?

You're talking about different vaccines. There is not one single vaccine they've been banging away at for 20 years. And there is not one singular 'they' developing vaccines, there are multiple different teams developing multiple different approaches, who are doing animal trials as part of standard vaccine development. Plus in at least one vaccine (possibly all but I don't know), extra animal trials to check specifically for ADE, which is the problem I think you're referring to in the original SARS-1 vaccine attempts.

You do not know what you are talking about here. Please stop scaring people, and yourself, by cobbling together random things you have heard from different places and declaring the bad scientists are going to kill us all.

Bad scientist trying to kill us? Where have I said that? Im not scared of a vaccine I wont be taking. You should be scared about believing a government that doesn’t know what day it and pushing a vaccine no one knows what the long term effects are and you can’t legally sue them if it makes you or your children ill. Swine flue vaccine was safe until children started developing life effecting narcolepsy.

I’ve said they are rushing a vaccine they have spent 20 years trying to make particularly since SARs. And yes multiple big pharmas were involved. But still no Covid vaccine.

You have one of the biggest investors and drivers of the Covid vaccine even saying they will cut trials short if they start to get promising results.

But hey if you want to be the guinea pigs that’s your business I’ll sit back and watch