All these people taking weight loss appetite suppressant drugs?!!

[OnHerSolidFoundations]

Is it me or is this a bit sinister?

I think to be fair, most people understand that its short hand for 'most type 2 diabetes is lifestyle caused/contributed'

There are always exception to the rule and outliers and you are one of them

Just picking up on your point about metformin, my OH has had the same for many years, he has been on metformin for probably about 20 years, awful gastric issues caused by it.

I was prescribed it many years ago due to PCOS and trying to get my weight down as a comorbid factor of that, I stopped taking it due to the side effects. I often wonder if I should have just braved it out and tolerated it but I couldnt.

It's a horrible horrible drug to be on. And the joke is that Wegovy is now available to diabetics in our NHS trust but guess what, they can't guarantee sourcing it so aren't risking starting people on it. My diabetic nurse said I'm an ideal candidate due to my good lifestyle and intolerance of Metformin

If Ozempic/Wegovy was a cancer treatment and people were going without because it was being used as a weightloss drug..... there would be outrage.

I've already explained all this, re-read the posts.

My partner is on both though, so you might not come off the metformin.

Both statements are incorrect. Wegovy doesn't cause weight loss, it just makes it easier for people to achieve a calorie deficit. They still need to eat healthily and exercise. If they carried on as they were then they wouldn't lose a pound. Injectibles aren't something you take instead of dieting.

I think this thread is another in the same vein of ones we see nearly every day on here, Fat people are wrong

They're wrong for being fat in the first place and then they're wrong for losing weight in the wrong way.

Just wrong'uns all round

And as evidenced by posts above, there is a belief, god knows where from, that somehow drugs (or surgery, this often is said about WLS) just make you lose weight in and of themselves.

YOU STILL HAVE TO EAT LESS!!

And whatever route you take, SW, WW, Jane Plan, Cambridge Diet, Slim Fast, fasting, calorie counting, low carb, low fat, surgery, medication, you still just eat less than you need and that loses you weight. Some of those routes can be tolerated better by some, one size does not fit all and there should be no shaming and judging for how someone loses weight, its bloody hard work all round and life long for most of us.

Here's what you actually said "Well, you might think that's what you mean but it's not what you actually wrote."

Ok, enough is enough. I'll leave you to it - whatever it is.

Selective reading I see.
Can you just move on please?

And that’s exactly why this drug is used

I'm concerned by possible side effects that are, as yet, unknown. It's like anything though when it comes to risk, some will be more cautious than others. I personally wouldn't take it because I had side effects from taking fat binders in the late 00's (liver issues) which made me cautious about lots of meds and potential side effects. We are all different.

i am the same - I’ve already got digestive issues so for me the risk isn’t worth it. But I also chose not to vape as an alternative to quitting cigarettes for the same reason.

You still get to eat whatever crappy food, albeit less, you want and you just inject yourself after.

Not true at all.

If you don't eat well on Wegovy you don't lose.

It has already been shown to be far more dangerous than amphetamine - which is the drug previously used for weight loss, not meth - which had the attached problem of addiction, but none of these severe side-effects of Ozempic et al.

Amphetamines don't cause stomach paralysis, gallbladder issues, and suspected thyroid cancers, etc etc.

I'm old enough to remember the Fen-Phen phase - a weighloss miracle drug, so they thought - until it was banned, after it was found to cause heart problems.

Here is a list of weightloss drugs that have gone onto the market and then been found to have serious side-effects or problematic results. It's not unusual:

https://www.ncbi.nlm.nih.gov/books/NBK581942/

@violetlozenge- if there is such a large body of evidence that these GLP-1 medications are dangerous- why are they also being handed out to diabetics in increasing numbers? Surely if they are that dangerous, they are dangerous for everyone?

I think if you are being prescribed a drug for its known and researched use, and under the supervision of a doctor who is aware of its potential side- effects, then that is a very different situation than someone sourcing the drug off the internet because they want to lose 30lbs.

If only the government made meaningful changes to rules around food production and supply.

The real issue is that most people now eat ultra processed food and shops and adverts and national holidays and cafes are full of crap, calorie laden food. It's so hard to resist eating a crappy diet when it's become societies norm.

Cut the issue off at the root. Rather than trying to fix people decades into the habits/addictions.

I think what's sinister is the people who won't want these drugs to work. There's enormous money in the diet industry (look at all the books) and then there's the junk food industry.

I also think a lot of people don't want people to lose weight for other reasons. They like shaming people who are overweight.

I think these drugs will get better and better. And more available. And be used as a preventative by some. I take pills for high blood pressure and for under active thyroid daily. The new drugs will become thought of in the same way.

I don't think this idea is realistic though.

I've heard that
I think the theory is you don't want to be underweight, break a hip/fall/get unwell and lose more weight because you're unwell
Reserves to lose instead

My nan had a stroke and wasn't particularly tiny (maybe 8-9 stone) but she went down to 6 stone after the stroke before she recovered. Now if she had been 6 stone to start with...

I think that's wishful thinking. There has already been one lawsuit filed from patients who developed gastroparesis:

Ozempic, Mounjaro manufacturers sued over claims of "stomach paralysis" side effects - CBS News

Long-term effects of these drugs used for weightloss are as yet unknown, but the known severe side-effects along with the black box warning for possible links to thyroid cancer would give me pause.

There is also the case of developing "Ozempic face":

Plastic surgeons warn 'Ozempic face' has taken over Hollywood (nypost.com)

"I think these drugs will get better and better. "

This is why I said the above @violetlozenge.

Do you think the blood pressure medication we have now are the same as the original ones? And other similar drugs? There's already huge efforts being made by plenty of other big pharmaceutical companies to produce more drugs doing the same. Drugs that are tablets are in use/coming to market. Ozempic/wegovy already, of course, has the competitor Mounjaro which has produced slightly different results. These drugs are still in comparative infancy.

As I say, lots of vested interest from various quarters to pour cold water on these drugs. Lots of industries will lose money.People like to feel overweight people should go through a punishing regime to lose weight.

Plus one lawsuit?

Oh I've just read your other posts @violetlozenge. 🤔

Then you will know I am averse to unnecessary risk. The weightloss drug I used and liked when I was young was taken off the market ultimately - but it did not cause the severe side-effects of these newer drugs, just addiction potential.

I think if one was morbidly obese, and under the supervision of a doctor, the benefits might outweigh the risks.

Not sure what that face is meant to signify...

People often lose weight in their face. It’s the first place people noticed my loss too. Happy to have Ozempic face it’s a bit more wrinkled now too. The thyroid cancer link has been debunked already. For anyone reading and wanting to try it speak to an endocrinologist or bariatric specialist. These drugs are only going to get better and better in the coming years.