I'm 45. One DS, 10 with SEN.
I work FT and have supported DH through a career change as the sole breadwinner.
No family support and suffered bereavement young ( lost my mum at 19).
I have a stressful life situation - but I have learned how to get balance and be happy.
My advice:
Menopause and peri menopause suck. Have started HRT and my goodness it's made a difference. Don't mess about - it's worth it. Very simply it's a hormone deficiency- and totally treatable.
Find activities that bring you joy - and do them often. For me it's sea swimming. I get up early most days and meet two like-minded ladies on the beach when conditions are good. It's amazing and sets us all up.
Find a sport you enjoy. Not for physical health but for mental health. For me it's running and walking.
Invest resources, time and money in your physical and mental health.
Get a pension.
Don't give up your financial independence
Use sunscreen
Have goals - ie mine is to travel more - this will be cheap ( camping!) but a nice way to see Europe.