I’ve lost 7 stone on Mounjaro and plan to be on it for life. AMA

[LifeOfAShowGirl]

:)

But the healthy eating IS the medication. It doesn't melt off fat. It reduces your appetite so you can make healthy choices and not want to constantly eat. That's exactly what the medication does.

Well done OP

this thread shows there is still a lot of people who don’t understand obesity and how these drugs work. It really isn’t a case of ‘eat less and move more’ for people who are predisposed to being obese and have had a lifetime of it

these drugs don’t just suppress your appetite or make you crave salad. They work on how you actually process food and your blood sugars

Emerging studies show that those who come off the drugs will put the weight back on. Something like 97% of people which is rather depressing . And no ‘cementing in good habits’ will change that

I lost 75 lbs last year and I take a maintenance dose now.. I’d certainly like to work towards taking as low a dose as possible and of course not take any at all but I’m taking it slowly for now

And yes - the making better choices and eating well IS the drug doing its thing.

and it’s almost impossible to explain that to someone who hasn’t taken it

@LargelyBusiness don’t forget that the clinical trials will all have had a placebo group for comparison. Mounjaro significantly outperformed those on placebo. If it didn’t it would have been unlikely to have been approved as a treatment for weight loss.

They will put weight back on if they have not changed the eating habits that led to obesity.

While I don’t disagree that some physiognomies are more inclined to store far than others; that women are are more inclined to do so than men; and that post-menopausal women more inclined to do so than younger women: at the same time to get obese you have to eat far too much food and not do enough exercise.

If that is conquered, and there are many examples of people slimmed down from obesity and maintained the loss naturally, then there’s no reason to suppose anyone would need life dependency on these drugs.

Do you have a source for these claims?

4 mmols is borderline hypo - in older people that is considered a hypo

I've been on drugs for various things and am currently on medication for high blood pressure and under active thyroid long term. My Dh has been on very many very serious long term medications for over 12 years. We are both hard wired to look for side effects in the leaflets that come with the medications. And any changes in advice.

I'm just about to take the plunge ordering mounjaro; to see if I can get approval that is.

Maybe people who bring up side effects aren't used to that being a given that they can occur? It's a risk assessment that we have to take. People seem to think in 2025 that we shouldn't take any risks.

Well done op and the rest of you! Stories like yours are giving people hope.

“4 mmols is borderline hypo - in older people that is considered a hypo”

And?

When i was skinny in the past i generally sat around 3.7-4.0mmol/l fasting glucose, so i think it is right for me. I was hungry but not desperate.

Are you aware of what hypoglycaemia is and how dangerous it can be?

Do you have any medical qualifications?

I'm perfectly aware, thanks. It's part of my job!!

Yes I'm aware and I'm sure @Periperi2025 would be in consultation with her hcp about it.

And by the way ...

"Hypoglycaemia in the absence of diabetes is diagnosed by the lower blood glucose of <3.3mmol/l" JRCALC update 02 Apr 2025

Hope that alleviates your faux concerned for my welfare.

Are these also unmedicated side effects of unmedicated obesity?

@PopstarPoppy

Also from the study you referenced:

"Compared to usual care, GLP-1RA use was associated with a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimer’s disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions."

Fat people are capable of reading about risks and benefits of anti obesity medication and then making a decision that works for them.

Good grief. Just caught up with the thread, the op, like me, was fat, not stupid. I wonder how many people angrily demanding the op comes off the drugs, are overweight themselves or struggle to maintain a healthy weight and are resentful she can do it with drugs. How many given the chance would jump at taking the drugs.

she’s made an informed choice. She clearly knows more about the drugs than those angry with her. From what I can see this is ask me anything, not “ explain the drugs I’m on and demand anything of me”

op. Well done in taking control of your health. Genuinely enjoy the new healthy you, this medication is one of the biggest medical science advancements in decades, for such a simple thing, a synthetic peptide, a peptide we produce naturally, the health benefits are amazing for us as humans, and we are all just at the start of this scientific journey. Obesity rates are starting to reduce across the globe, soon our,populations will be fit and healthy again, obesity a small percentage of people, and with it we will see th4 reduction in cancer, diabetes, heart attack and strokes, to name just a few things.

obesity is the biggest killer we face as a population, the number one and biggest cause of cancer. And that’s before we discuss the other signficant health issues it causes, death, disability, pain.

so keep going, you got this.

This is a great post as it illustrates how difficult it is to really understand how it works and feels until you have tried it.

I read about it for months and months before taking the plunge. And wow… it’s just instantly possible to do all those things. Make the good choices. All the self sabotaging behaviour, willing you to eat crap recedes.

and it’s unfortunately true that many don’t do this. They just start jabbing and eat less of the same crap and lose weight. But if you make the effort alongside the jabs to make good choices it’s so very much easier and rewarding. I really enjoy food now and do not miss or even think about the things I used to crave.

It’s not about it costing so much - if that were the case then everyone who bought an expensive gym memberships would continue to attend. And it’s no placebo!

I do see both sides of the argument for stopping or staying on it for life. I think it’s a case by case thing for each person. I was not obese for most of my life. Only for a few years perimenopausal. So it’s my intention to try weaning off and monitor - but make sure I have a back up plan to get back on (some providers will let you restart within a timeframe if you need to - not making you wait until obese again) . However I do believe for many, obesity is a lifelong genetic condition and staying on will be the only answer. No one would tell them to come off medication for other chronic conditions once they were on top of the symptoms. And if it turns out to be necessary for me I won’t hesitate to go back on.

interesting thread OP. I’ll keep following to complete my bingo card - noones mentioned ozempic face yet? Disappointing!

I wish someone would’ve mentioned the Mounjaro arse. U didn’t have much there to begin with but it’s gone!

Which claims? Surely you can Google.

Btw I don’t know where “physiognomies” came from it was supposed to say physique.

The claims you’re making.

Yes, which ones?

About health impacts etc. it’s typical to back up your claims with evidence.

I’m curious, how do the injections actually reduce “food noise”? And have you noticed any loose or sagging skin from the weight loss? I’d be a bit worried about the skin losing elasticity and ending up with extra skin after a severe weight loss.