Y chromosome

[Watchfulwaiter]

To avoid current derail of thread about Dr Em

The first scientist to discover that the Y was the sex-determining chromosome was a woman called Nettie Stevens who studied mealworms.

Is that the sort of thing we're after?

scientificwomen.net/women/stevens-nettie-102

The thread is because there’s somebody on another thread claiming a Y chromosome is a broken X. I wonder where the other arm goes. Does it just float around the testicles aimlessly?

Ah, would have made more sense if I'd read the other thread.

I read somewhere that the Y chromosome is a mutated X, so men are just women with mistakes! Sounds right to me.

The female X is in possession of about 2,000 genes. The male Y, — once a normal X, has corroded over time into the shriveled lower-case-letter it is today. The Y coming gift-wrapped in the sperm of most any dude you now know has lost about 1,955 genes — ie, over 97% of itself. Currently, the Y chromosome is a trainwreck of about 45 surviving genes. (Some geneticists count 27). These hangin-on-by-their-pinkies-genes are primarily devoted to sperm-making. The rest of the Y chromosome is a wasteland of meaningless repetition. This rate of repetition is between 99.94 – 99.997%. Scientists were shocked by this repetition, and at first, could not distinguish one male from another, — not even from opposite ends of the planet. Sequencing the Y took longer than planned due to the excruciating tedium of this repetition. This repetition is the frantic but failed attempt of the Y at do-it-yourself self-repair.

trustyourperceptions.wordpress.com/2013/09/01/dudesaredoomed1/

Yup because wordpress blogs are the best place to learn about all sorts of things.

Must not get sucked in. Going to bed.
xkcd.com/386/

EndoplasmicReticulum

So you're saying it's not true? I've read this in a variety of sources, not just on a wordpress blog.

Endoplasmic you bastard! I need to go to bed too, and now I'm going to spend an hour surfing xkcd. (Just hit random and came up with this gem... xkcd.com/492/).

I mean it's either true or it isn't. It's not like biology is a grey area is it.

You don't think it's factually correct. That's the funny thing about biological truth and facts though, they remain, and through all the hyperbole they cannot be changed

Women have about 1.5% more genes than men, — the same difference between women and female chimps, — or men and male chimps. Humans don’t have that many genes to begin with; plants have more genes than humans. An approximate 1.5% difference is major — major enough that it can result in an entirely different species.

The Y chromosome has degraded over millions of years. This isn't contested:

www.smithsonianmag.com/science-nature/y-chromosome-may-be-doomed-180967887/

In 2004, in an article titled, “The Degenerate Y Chromosome – Can Conversion Save It?” Graves responded to Page: “(The discovery of palindromes) will not lead to a drive towards a more functional Y. The forces of evolution have made the Y a genetically-isolated non-recombining entity, vulnerable to genetic drift and selection for favorable new variants sharing the Y with damaging mutations. Perhaps it will even speed up the decline of the Y…”

WordPress blogs as article sources
Seen it all now.
I have a WordPress blog, anyone can write anything on there.

Yeah but the blog I linked to references all the scientists in the field, along with their pictures and research history, so if you want to research further yourself using scientific journals etc knock yourself out

You literally expect me to go and find journals for you, and the names of scientists and so on, when you can just do all that yourself

The rest of the Y chromosome is a wasteland of meaningless repetition.

FWR derailers in a nutshell.

I think this is the topic women are really not allowed to talk about

They come rushing in don't they? It's like a big sign saying "Don't go there".

I think the Smithsonian Institution in Washington is a pretty well-respected source. But let's all pretend it was just made up on Wordpress so we don't have to engage with any facts or discussion.

It’s not the number of genes that matter, it’s what they do. A single gene is the difference between having, or not having, cystic fibrosis, sickle cell disease, Fragile X syndrome, muscular dystrophy, or Huntington disease.

A Y chromosome isn’t an X with a bit missing. It has the sex determining gene. The SRY has profound effect on male development. It takes the Male down a completely different developmental pathway. We talk about that every day on this forum. It’s why women’s sport is going to go down the toilet if biological men are allowed to compete. It’s not some inconsequential gene like the one determining eye colour.

The number of genes are irrelevant. What the hell kind of argument is that women are more like plants than men are because they have more genes?

Are women with Turner’s Syndrome less than other women because they have only one X chromosome? Are men with Klinefelter’s more than women because they have XXY karyotype? Or how about XXXY? They must be really bloody special; they must have the combined superpowers of a man and a woman, mustn’t they?

The reason the Y has so few genres is that it has evolved to deliver one specific gene that makes a world of difference. If it had a shit-load of other vital genes only one half of the population would inherit them. Thats why the genes that are exclusive to the Y chromosome, such as the SRY gene, are largely concerned with sexual dimorphism.

All men have an X chromosome. They have all the genes that women have, but they also have a Y chromosome that suppresses some of those genes and expresses other genes that women don’t have.

Facts from the article, feel free to dispute if you can:

"the Y chromosome has degenerated rapidly, leaving females with two perfectly normal X chromosomes, but males with an X and a shrivelled Y. If the same rate of degeneration continues, the Y chromosome has just 4.6m years left before it disappears completely. This may sound like a long time, but it isn’t when you consider that life has existed on Earth for 3.5 billion years.

The Y chromosome hasn’t always been like this. If we rewind the clock to 166m years ago, to the very first mammals, the story was completely different. The early “proto-Y” chromosome was originally the same size as the X chromosome and contained all the same genes. However, Y chromosomes have a fundamental flaw. Unlike all other chromosomes, which we have two copies of in each of our cells, Y chromosomes are only ever present as a single copy, passed from fathers to their sons.

This means that genes on the Y chromosome cannot undergo genetic recombination, the “shuffling” of genes that occurs in each generation which helps to eliminate damaging gene mutations. Deprived of the benefits of recombination, Y chromosomal genes degenerate over time and are eventually lost from the genome."

"shrivelled" - oh dear

Not allowed to talk about?
Why? Sorry, but if you come across as talking utter bollocks you're going to get questioned like someone did to your post on the other thread.
All I said was any Joe Bloggs could put together a WordPress article, which they can.

m.youtube.com/watch?v=nQcgD5DpVlQ

Lots of fun facts about the Y chromosome on this Ted talk:

Still doing it I see Roses.

There's an article there from the Smithsonian magazine saying pretty much the same thing. Are you able to engage with that?

I think this is the topic women are really not allowed to talk about

If a day has gone by since I joined this forum in which we didn’t discuss Y chromosomes, I must have missed it.

The difference between XX and XY is the molecular basis of women’s oppression.