Y chromosome

[Watchfulwaiter]

To avoid current derail of thread about Dr Em

So all down to the feelz?

And the Y chromosome can recombine. So your grasp of the biology seems confused.

Is that a biological truth that can't be changed?

But they're not on their way out. And I'm pretty sure that any desire to destroy the planet has very little to do with understanding the small number of genes present on Y chromosomes.

golgiapparatus

The Y crossing over, isn't this something scientists tried to achieve but failed at

Yeah I know men have an X, but we've got two

The Y, despite its best efforts, cannot repair itself, and so dumps all mutations from one dudegeneration into the next. “Adam” passes all his mutations onto his son, who passes his father’s mutations and his own mutations onto his son, who passes his grandfather’s mutations, his father’s mutations and his own mutations onto his son… The destruction, because it is cumulative, is astronomical. Each dudegeneration becomes more and more damaged. Each dudegeneration becomes weaker and weaker.
The X chromosome, on the other hand, has the lowest mutation rate of any chromosome in the entire human genome.

Yeah I know men have an X, but we've got two

...so...?

Mutations=evolution

inkering scientists, in thawing and nudging the Y, were trying to induce Y recombination, and btw, maybe rescue dudes. It also seems likely that tinkerers were on a reconnaissance mission, trying to see if they could move Y’s 45 dying-ass sperm-making genes onto the X chromosome – getting the X to do even more shitwork for dudes. (The X already provides genetic material dude needs for, for example, making his brains (40% of the X is devoted to brain-making), making his balls, and making his future sperm tails lash. (That’s right. Man’s raison detre – and they can’t even make their own balls. “He’s got BALLS.” Sure he does… From mother)). Given the precarious state of the Y chromosome, many genes4dudes once on the Y are now eating out of the fridge over at dude’s other chromosomes. All by themselves, they got up and left. Perhaps tinkerers hoped, if arranged for before the Y totally discombobulates, this colonizing-another-chromosome final strategy could keep dudes around. Since the X isn’t turn-key quite yet, scientists interested in saving their danglies may have to look at hotwiring another chromosome from dude’s own lot.

GottaGetUp

I don't think that's what she means by mutations, I think she means "problems"

No it's not. Crossing over can occur. Rarer because of its smaller size but that is true for all the smaller autosomes.

You do realise that we all (males and females) have 22 autosomal pairs of chromosomes and then the sex chromosomes? So to suggest that males aren't having variation through independent assortment and crossing over is total rubbish.

You also seem to misunderstand 'mutation'.

Not all mutations are deleterious.

You really don't understand the biology and it might be better if you read a little more on the topic.

I'm not so sure it's rubbish

So she's literally wrong then?

Cor blimey, this got weird

Thanks to the scientists posting, it’s very interesting

We all (if we are genetically 'normal') have 46 chromosomes. Of which only two are sex chromosomes. Variation in living things occurs because of mutations in sections of chromosomes which code for proteins. These mutations can give rise to new alleles. These can occur over all 46 chromosomes. Suggesting that variation is limited to the sex chromosomes is total and utter nonsense.

She makes it clear that when she talks about mutations she's talking about the inability of the Y to repair itself.

Nobody is talking about beneficial mutations, which is a random derail

You are repeatedly conflating the Y chromosome with "male", but the Y chromosome actually constitutes a very small fraction of the genetic material in any male human (or dude if you prefer).

God no I totally agree with you that mutations can be beneficial in nature.

But that's not what she's talking about here.

the Y chromosome actually constitutes a very small fraction of the genetic material in any male human (or dude if you prefer).

Yes that's been covered below. The Y doesn't have many genes at all

Very much from a lay persons point of view, I'm completely certain that at some point human males were able to evolve, due to the fact that I'm not married to a primate

I'd also suggest that the fact that the variation in appearance among humans being as wide among males as females, shows that too

So are you suggesting sakura184 that at some point human males have stopped evolving?

All DNA can repair and we have enzymes that specifically do just that.

I will echo what others have said, you seem to be mistakenly assuming that the Y contains all the genetic material in a man. Which is doesn't.

When it does contain is the SRY region which drives the production of the Male phenotype. Presence of a Y equates to the production of a Male phenotype (so long as there is no other DSD) butbit doesn't hold all the genetic variation of males.

Really, you should read some basic biology.

The number for genes does not indicate biological relevance. It's what the genes code for and how they are expressed that matters.

So are you suggesting sakura184 that at some point human males have stopped evolving?

Yes

But any mutation in an individual Y chromosome which is deleterious to the extent that it is incompatible with life will lead to an unsuccessful pregnancy, and any that is deleterious to the extent that it is incompatible with reproduction will not be passed on. Leaving all the other non-mutated Y chromosomes to continue human reproduction.

You talk as if all Y chromosomes are simultaneously mutating in the same way and one day will all accumulate so many mutations that all men will suddenly disappear in a Thanos click.