Self dosing 3.75mg on a 5mg pen?

[Gizmosgremlins]

Hello all, I've been on mounjarno for 8 weeks at 2.5mg. Weight loss was great first 6 weeks but nothing for last 2. I have however continued to feel sick. I want to increase dose but worried about feeling even worse. Pharmacist and google tell me taking anything other than the prescribed dose is a big no no. My preference is to use the clicks to take a partial dose of 3.75mg. Is it commonly done by folk on here? Has it worked for others? Thanks.

It's absolutely done by plenty of us on here. There's the people like you who want to go up slowly to balance SEs with effectiveness and there's people like me who've reached maintenance but are trying to minimise costs by using a higher dose pen for smaller doses. And loads somewhere in between. 😁

It's technically against the "rules" because of the official line on using an open pen within 30 days but some pharmacies are getting more relaxed about that. As long as you practice good pen hygiene and keep the pen refrigerated (that's my opinion anyway) you should be fine. Ultimately it's up to your own risk assessment but it's very common now.

Monj even has a click calculator:

https://monj.co.uk/mounjaro-click-calculator/

You don’t even have to go as high as 3.75mg. My OH went up to 3.25mg and found it very effective for many months, and after a year is still only on 3.75mg.

Great, thanks both! Feel much more comfortable doing that than jumping straight up to 5mg

If you feel sick then dont increase. Maybe do less..

I used 3.75 for a few months and was fine, however stopped working so jumped up to 5 a few days ago.

i am floored. I’ve actually called in sick to work as that exhausted. Does anyone used an intermediate dose between 3.75 and 5?

I was doing 4mg for a while. 48 clicks (of a 5 pen).

Divides nicely into the 5mg pen so you get five complete jabs instead of four.

You can use a pen for any dose you want if you calculate dose per click. I take 33 clicks from a 5mg pen. 30 clicks is 2.5mg so 33 is 2.75 mg.

I do this. 45 clicks of a 5mg pen once every 10 or 14 days. I know that means the pen is open much longer than 30 days but it's working for me. Although I'm not trying to lose - just maintain and not binge etc

I went to 3mg initially, then often just increased by a click or 2 when I needed to increase, keeping a record of my dose on Shotsy and a spreadsheet.

I take 3.75mg and it is working for me.

First pen 2.5mg - Felt OK but lost very little weight.

Second pen 5mg - Felt completely wiped out for the whole four weeks. Lost very little weight.

Third pen 5mg - Take 45 clicks = 3.75mg. Minimal side effects. Losing one or two pounds per week.

Good luck OP !

As 2.5mg is only a therapeutic dose , if you are losing on it, then that’s great. No reason not to increase by halves.
I had the opposite issue, I followed the manufacturer instructions when I started in April 2024 and lost nothing, even gained ! .. didn’t begin to lose until 7.5mg but soon plateaued ,went all the way to the top where I lost about 20lbs a month. I never had a side effect beyond mild constipation.
Basically, the reason I say this is to demonstrate how people seem to respond so differently, therefore altering your dose once you know how your body responds makes sense.

i would just say that I couldn’t of put up with a 1 or 2 lb loss per week for the cost ! I could do that with weight watchers/on my own and with 8 stone to lose would have cost me squillions and taken over 2 years. I lost 80% of mine over 5-6 months on 15mg at 15-18lbs a month.