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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weygovy help!

1 reply

Luna95 · 01/05/2026 06:53

looking for some advice/reassurance/shared experience please! I have just completed my 4th week at 0.5mg after completing 4 weeks at 0.25mg. I felt absolutely fine for the first 6 weeks, however following my 3rd dose of 0.5 I developed a gnawing stomach ache and horrific sulphur burps which was revealed after vomiting. I felt rough for the following day or so but then symptoms resolved. This week after taking my 4th dose of 0.5 I again developed the gnawing stomach ache, the day after the jab I felt awful - shivery, weak and vomited. Symptoms resolved a little but I still didn’t feel 100% by the following day. My appetite was non existent making it really challenging to eat anything at all. I had a couple of episodes of feeling as though my vision was slightly blurry and developed numbness/pins and needles in one hand. Both of these symptoms resolved quickly but did frighten me! I think maybe electrolytes were thrown off by lack of nutrition? But wondering if anyone’s had similar…. Every evening for the next 4 days after that 4th dose the gnawing stomach ache returned and I’d end up vomiting. By day 5 I felt totally normal again… very strange.

So… I am now in a predicament of wanting to continue with treatment but I am extremely anxious that I’ll feel so unwell again. I have already requested to reduce back to 0.25, I feel like I didn’t really need to increase from this when I did as I had no side effects and was losing weight steadily. Has anyone else felt horrific at 0.5 but okay when reducing back to 0.25?

I don’t know whether to take a break for a few weeks as we’re due to go on holiday in a couple of weeks and I don’t know if I want the stress of worrying about side effects etc….

what would you do?!

thank you so much if you’ve made it this far!

OP posts:
Woo383040 · 01/05/2026 08:59

I’m on Mounjaro not Wegovy and almost at maintenance, but have had a similar experience when I first started.

It sounds like your lower dose was giving you plenty of suppression and you didn’t really need to increase, and the higher dose is too strong for you at this point. Wegovy has a half life of 7 days, so half of the previous weeks dose is still in your system when you take the next dose, which I imagine is why you then have the bad reaction when you do.

I had very similar when I started Mounjaro and had a holiday coming up too, and chose to stop, and restart after the holiday, on a lower dose. With hindsight I would have reduced the dose. Can you take a half dose from a Wegovy pen? That way you can see if you get on ok with it, but still have time to stop before your holiday if you’re still having bad sides.

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