On Mounjaro for 15 months and now symptoms??

[Vivienneon]

Wondered if anyone else has experienced this or can offer insight.

I’ve been on Mounjaro for around 15 months and have been very lucky with minimal to no side effects. Was on 12.5mg dose for a while but recently went up to 15.mg. About 4 days after my first 15mg dose I developed horrendous diarrhoea, which I’ve had on and off for 6 days. I do have gut issues so it might be related to that (although this level of out-of-the-blue diarrhoea is unusual) or it might be a bug and totally unrelated to Mounjaro. Is it likely that I’ve been fine on Mounjaro all this time - going up through all the other doses etc - but that this dose increase has caused this?

Possibly. Did you need to move up a dose? Could you go back down?
Could also be a bug

@MrsMiagi well I wanted to try it as my weight loss had stalled but if I suspect it’s the cause of this (it’s v grim) I’ll definitely go back down.

Hey, I have been on Mounjaro a similar amount of time and in maintenance on 15mg for the last six months or so. No/very few (and very transient) symptoms for the first 13/14 months. I went down to 12.5mg in months 14 and 15. In month 16 I was turning forty and wanted to lose a few extra lbs in advance of my big day, went back up to 15mg and have had symptoms since. I stayed at 15mg this time, too (month 17). I’m not really sure why I did tbh, I think I just did the “reorder” and got 15mg. Anyway, I am having a solid 48 hours of feeling pants afterwards; nausea, headaches etc; and weird bowel movements all week (soft and frequent, then constipated and bloated).

I contacted my provider who looked at my BMI etc and suggested I was potentially using a dose “too big” for my current BMI and that my body is struggling trying to process such a big hit now it’s much smaller (BMI 19.8).

I’ve been advised to go back to 12.5mg and see how I get on there.

Have you got quite a low BMI now? Could it be that for you?