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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

3rd week at 0.25 Wegovy, side effects but no weight loss

2 replies

redpickle · 08/04/2026 17:16

i took my third 0.25 dose of Wegovy on Friday. I’ve not had any side effects at all since starting except sulphur burps. I’ve also had no appetite suppression or weight loss. I’m tracking calories as I usually do but it’s still not shifting. Last night I had the most almighty D&V for several hours. I seemed to purge and there was nothing left! (TMI sorry). I’ve got one more dose at 0.25, then I’m supposed to go up to 0.5 the week after.

Not really sure what to do. Should I stick with the lower dose which isn’t really working for the weight loss but maybe I need longer to adjust? Or increase it and risk more D&V? I’ve ordered through Voy and their AI advice is to do another month at 0.25. That seems a bit pointless when it’s not causing any suppression at all. I cant afford Munjaro either at this stage.

I know I’m only on the ‘intro’ dose at the moment but it’s powerful enough to make me feel quite ill, but not actually reducing food noise or hunger. What should I do?

OP posts:
WappityWabbit · 08/04/2026 17:29

I think a lot of people tolerate Mounjaro better than Wegovy so if it’s definitely not working for you, maybe give MJ a go?

SilenceInside · 08/04/2026 17:31

Could you wait to see if things settle down after your next dose and then leave ordering the next pen until after you’ve done your 4th 0.25mg dose?

Or, is it possible with Wegovy pens to do a half dose? If so, then you could get the 0.5mg and decide on the injection day whether to do 0.25, 0.5 or even somewhere in between. Not sure how the Wegovy pens work so not sure if that’s an option.

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