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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Wegovy newbie

75 replies

Ellswells3 · 01/04/2026 19:09

Hi!
I hope it is ok to post, I know there are many similar.
I have never had WLI before but started Wegovy yesterday evening (0.25). I feel absolutely no different, no side effects, no reduction in appetite? I know it’s very early and it probably needs to build up but it is feeling very anti-climatic! Can anyone shed any light on/ reassurance on the Wegovy journey?!

Thank you!

OP posts:
soupmaker · 09/04/2026 09:44

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creamcheeseandlox · 09/04/2026 13:32

lechatnoir · 09/04/2026 08:56

I'm just looking into buying options for Weygovy so hope to be joining you within the week - any retailer suggestions or discount codes welcome. I can't really afford £100+ a month but just so sick of this extra weight I'm carrying and decided this is the summer to finally shift it especially as we're going away with friends in september and I want to look forward to it rather than dread & avoid being poolside (especially as one of the ladies is a mega gym bunny and looks AMAZING)

I have a referral code for med express. We both get £50 off I think....

jabsahoy · 09/04/2026 14:22

Having a nightmare (ie no response to chat bot tickets raised!) with ME not delivering so wouldn't use them @lechatnoir

If my pen is not here by end if today, I'll be requesting a refund and trying somewhere else- given their lack of response to the delivery issue I expect it'll take me forever to get a refund.

jabsahoy · 11/04/2026 22:03

Pen finally arrived earlier this evening so will be doing jab #1 tomorrow!

Possibly having a bit of cheese and crackers session now 😄

Tsulsaquoola · 12/04/2026 16:38

My 0.25 Wegovy pen is in the post and I plan to start Friday as I have a day off. I’m 56, post menopausal, and I’ve never weighed this much - I’ve battled with my weight my entire adult life and feel like I’ve tried everything. I always put the weight back on. I’ve just tipped over from overweight to obese - my BMI is 30 - and I thought enough is enough. I also have high cholesterol and a strong family history of heart disease and stroke. At some point I think I stopped wanting to lose weight for vanity reasons (though I can’t deny I’d love to be able to fit in my clothes again) and into wanting to lose weight because I’m frightened I’m going to die prematurely or have an extremely unhealthy old age.
l am, however, scared to death: side effects; that I’ll stop enjoying food (I like cooking and I like cooking for other people); that l’ll have to stay on it for life or, conversely, come off it and I’ll put all the weight back on.
I’ve only told my dh and he’s very supportive but I’m still feeling really worried. I do have a tendency to overthink, you may have noticed 🤣

LauraC1984 · 12/04/2026 18:41

I’m pleased your pen finally arrived @jabsahoyhow are you feeling so far?

hoodiemassive · 12/04/2026 18:48

@Tsulsaquoolathere is a new April Wegovy starters thread which you might find supportive.

Just try to remember that it’s one jab a week so if you do find the side effects too much then you can easily stop.

Am on my second week and have no side effects to report.

Tsulsaquoola · 12/04/2026 19:04

@hoodiemassive thank you, I’ll have a look for it

Ellswells3 · 12/04/2026 19:49

Is anyone else finding their thirst massively suppressed? Weirdly I still crave the food but I could go the whole day without having a drink - which obviously isn’t good! Wondered if others had this?! Trying to make a conscious effort to have a drink but for example today where I’ve been busy I had an approx. 400ml glass of squash with breakfast and then a Pepsi can around lunch time and nothing else! Normally I would drink around 2L!

OP posts:
Ellswells3 · 12/04/2026 19:49

To add - drinking is what makes me feel nauseous?! Quite annoying really as I only ever drink 0 cal drinks so won’t help my weight loss lol!!!

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LauraC1984 · 12/04/2026 20:20

Bizarrely it’s totally opposite for me! I’m thirst all of the time so I’m drinking loads and if I don’t drink enough, I start to feel nauseous which goes as soon as I drink more water! It’s strange how it affects everyone differently isn’t it! How you finding this week?

Ellswells3 · 12/04/2026 20:43

LauraC1984 · 12/04/2026 20:20

Bizarrely it’s totally opposite for me! I’m thirst all of the time so I’m drinking loads and if I don’t drink enough, I start to feel nauseous which goes as soon as I drink more water! It’s strange how it affects everyone differently isn’t it! How you finding this week?

That’s so weird isn’t it! I have to say I’m a bit annoyed that it is this way round for me!

This week has been ok, I haven’t been perfect but I do think there is some mild appetite suppression in the background (or whether it’s just I’m trying harder) because I haven’t been as ridiculous with food as usual and have been able to make better choices. How have you found it?!

My worry is that my eating is so behavioural, like it is very rarely hunger that makes me eat anyway and more habit / stress / boredom etc. I feel that I can eat even when I am not hungry so worry that even with appetite supression I’m going to have to really try hard with my diet. I understand you have to work with the drug but I was kind of hoping for some momentum from the drug to push me forward without having to feel like I am on a diet all the time!

Also has anyone started exercising? I know I need to start because of the risk of muscle loss but also I’m so unfit I find it hard. I hoped if I lost a stone it might start to feel easier as there would be less of me to move!!

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LauraC1984 · 12/04/2026 20:52

I feel pretty similar to be honest! I’ve had to change my role at work recently because of childcare and I’m now sat at a desk every day and it’s so boring, I literally graze on rubbish all day to keep myself going! Definitely not because I’m hungry!
I feel like there’s definitely a very slight suppression but I’m still tracking, calorie counting and basically dieting. I want to up my dose when my next pen is due but really worried about side effects too.
I have also done no exercise for way way too long! I really want to start Couch 2 5K again, I know it works for me but I’m so bloody lazy, I just need to start, also worry about how unfit I am, I think I’d really struggle!
it’s good to hear from other people who are in similar positions though, hopefully we can push each other on!

Ellswells3 · 12/04/2026 21:16

LauraC1984 · 12/04/2026 20:52

I feel pretty similar to be honest! I’ve had to change my role at work recently because of childcare and I’m now sat at a desk every day and it’s so boring, I literally graze on rubbish all day to keep myself going! Definitely not because I’m hungry!
I feel like there’s definitely a very slight suppression but I’m still tracking, calorie counting and basically dieting. I want to up my dose when my next pen is due but really worried about side effects too.
I have also done no exercise for way way too long! I really want to start Couch 2 5K again, I know it works for me but I’m so bloody lazy, I just need to start, also worry about how unfit I am, I think I’d really struggle!
it’s good to hear from other people who are in similar positions though, hopefully we can push each other on!

Yep sometimes it’s really hard at work as there is a constant supply of biscuits near our desks!!

Me too although I have also seen that some people experience a lot more side effects as they go up; although between us it’s clear everyone is different! I also think I need some of the negative side effects to actually make some changes lol! If I had a bad reaction to chocolate maybe I’d learn!

I would like to do couch 2 5k too! I am so unfit though I don’t know how I’ll manage it! The accountability and motivation would be good though!

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LauraC1984 · 12/04/2026 21:50

I really need someone to do C25K with but everyone I know either isn’t interested or is so much fitter than me that they would breeze it while I struggled along huffing and puffing!
I think I’m going to order a 0.5mg one next and try it for the first week, if the side effects are too bad I might count clicks and try 0.375 and see how I go with that

creamcheeseandlox · 12/04/2026 22:50

jabsahoy · 11/04/2026 22:03

Pen finally arrived earlier this evening so will be doing jab #1 tomorrow!

Possibly having a bit of cheese and crackers session now 😄

Would you be kind enough to share a med express referral code with me for my recorder. It's at the bottom of the home page. We each get £50.

creamcheeseandlox · 14/04/2026 09:43

I did the couch to 5k after Xmas after being out of exercise from my hysterectomy. It's so good and I am now running 5k 3 times a week.

I weighed in this morning. -2lbs. Plus the one fromazt week so that's -3lbs in 2 weeks. I have been in huge calorie deficit so would have been .miffed if I hadn't lost anything.Third jab tomorrow and have just ordered a new pen.

LauraC1984 · 14/04/2026 09:51

That’s amazing that you’re running so much now, I really just need to push myself to actually start it!
Well done on the loss, fingers crossed this works for us all without too many side effects!
Im due my third jab today too but I haven’t reordered yet, I’m not sure whether to move up to 0.5 or not, I feel like the suppression isn’t great now but I’m worried in case it makes me ill! What have you decided to do?

Ellswells3 · 17/04/2026 22:04

How is everyone?! I’ve started to get the appetite suppression which is definitely helping me keep my calories low, and I do find the food noise has reduced… so far no real side effects either. Keeping my fingers crossed it stays this way!

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LauraC1984 · 20/04/2026 12:57

That good news @Ellswells3 I’m pleased it’s working for you!
I started off so well and lost 10lbs in the first two weeks but have fallen off the wagon spectacularly this weekend! I’ve been away for a wedding and have just eaten rubbish, back on it today so fingers crossed I haven’t done too much damage!
I ordered my new pen last week, I’ve upped to 0.5 as I feel like the initial suppression isn’t as strong now, but I’m terrified incase I get awful side effects! Still have another dose of 0.25 to take this weekend first. Have you stayed on 0.25 or upped your dose?

Ellswells3 · 20/04/2026 16:46

Oh bless you, it is always going to be an up and down journey especially when celebrating life events like a wedding! I have stayed on 0.25 for now as it seems to be working and I am worried about side effects too…
let us know how you get on!!

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ZZGirl · 20/04/2026 21:35

So far so good for me, I've done two injections and lost 3.8lbs. I'm eating between 1200-1300 cal a day and my IBS symptoms have improved. Got another two weeks on 0.25

creamcheeseandlox · 21/04/2026 10:23

I weighed in this morning and not lost or gained anything last week. Stayed the same. I have been doing the exact same as I did the week before. Hoping it's still doing it's thing in the background and trusting the process. Disappointing though. I ordered a 0.5 for my next pen.

hoodiemassive · 21/04/2026 17:50

I have a 0.5 pen waiting for after my fourth jab on Saturday. But worried as I had awful d&v after my 3rd jab which I’m just getting over…don’t know if it’s a bug or side effects.

I have lost 6lb in total though so am pleased with that, just worried about moving up to 0.5 and wishing I had stuck with 0.25 for my next pen.

hellomylov3 · 21/04/2026 18:37

Hope everyone is getting on ok. I got my 0.5 dose on Thursday having tormented myself whether to go for it or not. I was sick once but that's it. I actually feel that the 0.25 was more effective but maybe it's my imagination.
(I had bad d&v after my first 0.25 injection and had been in two minds whether to try to cancel the whole thing. I kept going and was ok so decided to stay with it )

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