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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro 15ml not longer working - advice needed

28 replies

AnotherEmilee · 13/02/2026 11:18

I have been taking Mounjaro since July 2024 and have been on 15ml since Feb 2025.
I started at over 20 stone and have lost 4.5 stone. I was losing slowly but consistently until November 2024.

I have not lost any weight since the beginning of December and am finding the Mounjaro to be less effective, some of the food noise is creeping back and the food I am eating is not keeping me full for as long as it was.

I have made habit changes and am eating different foods but Mounjaro was heavily supporting these. Now I am eating the same heathier options but I am starting to feel hungry by late afternoon and with some of the food noise back it is difficult to always make healthy choices.

In January my weight started to go up so when I placed my last order I spoke to my supplier about this. They sent me an e-mail with a reminder of the standard advice about eating more protein, increasing exercise, drinking plenty of water etc. They did also say that I could try going back down to 10ml for a month then 12.5 then back to 15 to see if this helps.

I have been trying to make sure that I am drinking plenty and eating the right foods and this has helped a bit. I have stopped gaining and am back to the weight I was at the beginning of December.
I weigh every day and have been at 16 stone 2-3lbs for the past 2 weeks and it has stopped going down again.

I need to place my next order today and I don't know what to do. Should I order 10ml? I am worried that this will just make it harder and I will gain weight for the next 2 months (although it will make it a little cheaper).
Has anyone else tried this and did it work for you?

OP posts:
Blondeshavemorefun · 14/02/2026 12:24

AnotherEmilee · 14/02/2026 10:34

I lost 4s 9lbs in just under 18 months from 20stone 9 to 16stone.

I am happy with this rate of loss, some people may not understand but I wanted to lose weight slowly. I have weighed 18stone + for the past 20 years.
I am worried about gall stones or loose skin problems if I lose weight quickly. I am also dreading people starting to notice and comment on my weight loss. I am used to being the fattest person in the room and being the fat family member/friend. I wanted to lose slowly to allow time for my brain to adjust and keep up with my changing weight.

4.5 loss is great as in lost weight so well done - but over all being on 15 (I was for many months as went up each month) for a year and on mj 19 heading up to 20mths and 4.5s loss isnt that good as means losing less than a lb a week

there is slow and there is slow

I mean this kindly but it’s wasting your money if you don’t put the work into it by the food you eat

a lot of it is portion control and calories

as i said earlier if you eat less then you burn you will lose weight

a healthy loss is 1-2lbs a week. So even at 1lb you should have lost minimum

you started roughly same time as me and I’ve lost 7s (was 17.4 now 10.4) size 20+ now 10/12 an I’ve been maintaining current weight for 6mths or so

obv it isn’t a race but surely you can see that 4.5s in 18mths is slow

Blondeshavemorefun · 14/02/2026 12:25

Frenchfrychic · 14/02/2026 12:05

It’s also part of your problem though, you’re losing so very slowly, less than a pound a week so not even reaching the advisable min, which means you eat just below maintainance, and then as your weight drops, that maintenance does too, thus bringing you closer to no loss as you simply eat to maintenance.

you also don’t mention if you’re doing weight training or eating your protein sufficiently, meaning there is a high chance you’re losing muscle, which reduces your maintence cals again.

id really think about your reasons for going so so slow when spending so much money, and recognising it’s got you into this situation. Is it really you’re worried about loose skin, as going slowly won’t change that, working out will, is it really you’re worried about not being the fat person anymore;

or is it you just really don’t want to diet or reduce food, and are doing this simply as you feel you should.

You word it better than me

Frenchfrychic · 14/02/2026 12:29

Blondeshavemorefun · 14/02/2026 12:25

You word it better than me

I was literally thinking the same about your post.

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