Suddenly not tolerating 7.5mg

[LittlePetitePsychopath]

I’ve been on MJ since July. In November, 5mg stopped making much of a difference to my appetite so I went up to 7.5, which has reduced food noise again.

Last weeks hit hard, though, I felt badly nauseous all day, and I’ve not been able to eat much. This week has been the same. I’m also more headache-y.

I’m 18kg down; and about 5kg from target, ideally. Do I drop back down? Do the doses start to affect you more as you get smaller? My BMI is now 27, so I’m getting back towards “normal” for the first time in nearly a decade.

Thank you!

Anecdotally, there does seem to be some evidence of some people finding their dose hitting harder as they approach goal. It hasn't happened to me yet (I'm in my goal range and on 10mg) but I don't think you're alone on this. You could drop slightly by counting clicks, rather than dropping right back down to 5.

Ah thanks, @GiveMeWordGames, I'll research that!

I found it got too strong for me as I got closer to target, first 10mg made me have really bad indigestion and then vomiting so I dropped back to 7.5mg, after 3 months I had similar sickness on 7.5mg so dropped to 5mg by then I was more or less at target.
Maybe drop back to 5mg or take an in between dose like 6mg.

Ok this is really helpful. Im on 15mg and have been since December. For the last four weeks ive had an upset stomach a couple of days after injecting. At first i thought it was a bug but now its every week. Ive lost 5st so i wonder if I need to drop down next week and see if it help. I never meant to stay on 15mg, but i had a big loss from a bonus dose and decided to stick with it.

@Bluehels maybe drop back for one pen and see how you get on, GI pain is really horrible and if dropping down stops it it’s worth’s try, I continued to loose weight as I dropped down.
Good luck 🤞🏻

Have a read of the threads on split dosing. It’s not recommended by any prescriber so you need to risk assess for yourself but an option could be to go back to 5mg and take it every 5 days for example. It may build the level more gently without the spike from the 7.5mg brining the side effects so much.

5mg is 40 clicks from the 7.5mg pen (as 5 is 2/3 of 7.5 and 40 is 2/3 of 60). Apologies if you know this but I don’t like click charts - if people are dosing anything other than as prescribed I think they should understand what they are doing.

Thank you so much, I hadn't worked that out yet. I'm going to give this a try! Thank you x

I had the exact same thing OP. I’d been on 7.5mg for around 4 months and then for a full month just felt constantly nauseous. Even the sight of the pen in the fridge made me feel like heaving. I dropped back down to 5mg but that left me feeling too hungry (only lost 1lb that month as I was eating more than usual). I’m on week 2 of having gone back up to 7.5mg and so far so good! I’ve got decent suppression but no sickness so that’s good.