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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

5mg not working anymore

9 replies

Tranquilitybaby · 02/11/2025 15:15

I bought three 5mg pens in advance, before the price increased as the supplier allowed us to do so. But in the last month I’ve found that 5mg isn’t working as well now and much as I’m not keen, I think I need to go up to 7.5mg. I’m just worried about side effects on a higher dose.

I can’t use the pen and do extra clicks on a 5mg can I, I presume I need to use one of the syringes to give the dose? It’s 0.9ml isn’t it?

thanks

OP posts:
HeidiLite · 02/11/2025 15:18

you can, just need to inject twice. With new needle. Full dose plus second half dose (30 clicks)

Kazzaa46 · 02/11/2025 15:28

If you’re worried about side effects you could always try 6.25mg first to see how you get on. That would be an additional 15 clicks on top of the first full dose.

WeAllHaveWings · 02/11/2025 16:07

That's unfortunate you have a stock of 5mg and it is wearing off, always the risk with pre buying (I did it too).

What does "not working as well" mean for you? No more suppression (I think that lessens over time for many people, regardless of dose), or food noise/cravings consistently back and cannot resist? Or weight loss stalled?

Have you tried all the basics to try to help with food noise/cravings and to keep your blood sugar / hunger cues steady? The things that help me are (apologies if you know all this already!) -

  1. Getting my protein goals mostly from whole foods - no shortcuts using low volume unsatisfying bars/drinks
  2. Getting protein in at every meal and no skipping meals
  3. Lots veg or salad at every meal too to increase volume and fiber with non starchy veg, lentils, seeds, berries
  4. Some fats at every meal, healthy if possible - nuts, seeds, Salmon, olive oil drizzles
  5. water throughout the day
  6. no UPF "soft" too easy to eat meals that don't satisfy for long and trigger cravings for me, go for real meals you need to properly chew - fresh chicken breast, steak
  7. I avoid daily treats with sugar/sweeteners (food and drinks) as they noticeably increase cravings/food noise - even zero cal drinks do this for me. If I have a biscuit or two one day I am thinking about having them again the next day.
  8. If loss slows down/stalls I will recalculate deficit and track calories for a few weeks to make sure I am still on track
  9. Improving sleep and reducing stress can also help if those are issues
FoxRedPuppy · 02/11/2025 18:55

I used a syringe and did 0.9ml. Or you could inject twice (I don’t think you need a new needle as very little bacteria would be introduced between the two).

MeridaBrave · 02/11/2025 20:10

Just do 5mg once a week and 2.5mg (30 clicks) 3 days later. Either way it’s worth trying to stick to deficit, meet protein and fibre targets, drink gallons of water etc.

pterodactylpinky · 03/11/2025 08:46

HeidiLite · 02/11/2025 15:18

you can, just need to inject twice. With new needle. Full dose plus second half dose (30 clicks)

You don’t need a new needle. The instructions say if the dose is not complete and you don’t see a zero after taking it out to reinsert and finish the process. It would be no different do taking it out and dialling it to 30 clicks and reinserting.

Chopsy123 · 03/11/2025 09:08

Are you getting suppression for a few days in the week or none at all?

If it wears off after a few days, you could try injecting 5mg and another 5mg on day 4 or 5 if you don’t want to increase to 7.5mg straight away.

susiedaisy1912 · 03/11/2025 16:36

MeridaBrave · 02/11/2025 20:10

Just do 5mg once a week and 2.5mg (30 clicks) 3 days later. Either way it’s worth trying to stick to deficit, meet protein and fibre targets, drink gallons of water etc.

This.

BlessicaBlimpson · 03/11/2025 19:57

I was in the same situation as you, just bought a new pen in a higher dose and will keep the unused pen in the fridge until I’m ready to wean off (I’m quite near my target weight).

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