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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Best day to inject?

24 replies

FlutteryButterfly · 19/09/2025 22:14

Newbie Mounjaro user. Im not massively overweight but enough. Ive been supper skinny and chunky over and op!r again for the past 30 years. Bad relationship with food unfortunately. My question is when's the best time /day to start? I work Tuesday through Friday. My weekends are generally more indulgent then weekdays.

Help!

OP posts:
Mrsmunchofmunchington · 19/09/2025 22:21

Why would how much overweight you are or aren’t affect which day you will inject?

SilenceInside · 19/09/2025 22:21

I do a Friday morning so that suppression is highest over the weekend which is what I prefer. In the early weeks when I was getting some side effects occasionally, it also meant that side effects were usually over the weekend too.

FlutteryButterfly · 19/09/2025 22:26

Mrsmunchofmunchington · 19/09/2025 22:21

Why would how much overweight you are or aren’t affect which day you will inject?

That's not what I said/meant. Just asking which day would you inject if you worked tueday- Friday long hours with the weekend s generally more indulgent....

OP posts:
FlutteryButterfly · 19/09/2025 22:28

SilenceInside · 19/09/2025 22:21

I do a Friday morning so that suppression is highest over the weekend which is what I prefer. In the early weeks when I was getting some side effects occasionally, it also meant that side effects were usually over the weekend too.

Thanks this is what I'm leaning towards. Im not in s job where I can rush to the toilet... as in my next opportunity would be 3 hours away. I know thats a bit 🙄 but entirely true!

OP posts:
SkinnyOatFlatWhiteForMePlease · 19/09/2025 22:33

I started on a Tuesday but moved to a Friday I am generally ok during the week but struggled at weekends.

rewardh · 19/09/2025 22:43

FlutteryButterfly · 19/09/2025 22:26

That's not what I said/meant. Just asking which day would you inject if you worked tueday- Friday long hours with the weekend s generally more indulgent....

The ‘more indulgent’ view of weekends is a view that you need to switch. If you are using MJ use it as a life change every day, not just the weekdays.

I do mine on a Tuesday becsue it was delivered in a Monday and I wanted to do it on a morning.

Mysticmaiden · 20/09/2025 00:18

I do it on a Saturday morning and it usually kicks in by Monday, which I prefer as I want the control during my working week. I'm fine and in control at home but at work when I am busy/tired/stressed used to be when I'd have more carbs and treats!

Bread121bread · 20/09/2025 03:29

I started on a Friday afternoon. I'm a shift worker and I had just completed three long days and I had annual leave booked the following week.

I wanted a controlled environment as mounjaro is a diabetetic drug. My diabetes doctor told me to carry extra hypoglycemia treatment and to monitor my sugars more often. It was easier to do this at home. I'm glad that I did it this way.

Lanva · 20/09/2025 07:08

Thursdays, as the worst day for SE if I have them is the third day and before I moved to Thursdays I missed work.

FlutteryButterfly · 20/09/2025 12:11

rewardh · 19/09/2025 22:43

The ‘more indulgent’ view of weekends is a view that you need to switch. If you are using MJ use it as a life change every day, not just the weekdays.

I do mine on a Tuesday becsue it was delivered in a Monday and I wanted to do it on a morning.

@rewardh I know but what I meant is the weekends are where I currently fall down. So would aim to inject to suppress appetite at a time where it would really kick in time for weekends.

OP posts:
Iamthemoom · 20/09/2025 12:16

It peaks at three days so I would time it so days 2,3 are your weekend if that’s when you indulge. Also if you get any side affects they will be worst on the weekend. So inject Friday morning.

TheChosenTwo · 20/09/2025 12:32

I do mine on a Saturday night, my first delivery came and I wanted to sleep through any side effects if they came on soon after starting!
some people reported nausea and headaches etc soon after injecting; I didn’t feel like I needed to be awake to feel those.
i have stuck to a Saturday night 11 months down the line.

FlutteryButterfly · 20/09/2025 16:32

Iamthemoom · 20/09/2025 12:16

It peaks at three days so I would time it so days 2,3 are your weekend if that’s when you indulge. Also if you get any side affects they will be worst on the weekend. So inject Friday morning.

Thank you!

OP posts:
FlutteryButterfly · 20/09/2025 16:34

Friday is seemingly my best option. Due to the likelihood of me overeating over the weekend and my work pattern as I am not allowed to go to the toilet on shift!

OP posts:
MoreIcedLattePlease · 20/09/2025 17:48

Personally, I find Thursday evening works best for me. I get highest suppression over the weekend (danger zone!) and also fewer potential side effects through the working week.

FurForksSake · 20/09/2025 18:48

“I’m not massively overweight” is this an attempt to distinguish yourself from other WLI users? Surely to be prescribed you are either obese or with a bmi over 27 with a weight related condition?

I find a Friday worked best at the beginning so I had time to manage any side effects over the weekend.

cheekybtch · 20/09/2025 18:58

I do it on Friday afternoon on my lunch break whilst working from home. That way I know I'm going to be sober (ie not having a drink on a Friday night or Saturday, or hungover) and it gives me time to fight off any side effects without it affecting work. Fridays works for me. It also arrived on a Friday when I first got it so I did it straight away. Also means less likely to spend the weekend snacking when not working!

Lanva · 21/09/2025 09:26

@FurForksSake Drug response is affected by weight (and associated things like blood volume). It doesnt seem like MJ is, particularly, but it's not unreasonable to mention it in this context.

StarCourt · 21/09/2025 19:40

Had my first injection on Friday just gone as wasn’t sure about side effects and thought it was better to have the worst over the weekend. I also work Tuesday to Friday. I woke up Saturday morning with no hunger at all and it’s carried on until now. Food noise completely disappeared too, I’m amazed it’s worked that quickly

MeridaBrave · 21/09/2025 21:01

I do on Thurs so highest suppression at weekend

Bipaloss · 21/09/2025 22:06

I started Sundays as I snack while working at home , went back to Wednesdays (shortened interval 10-14 weeks in) and went forward after holidays and now jabbing on Fridays.

for me the jab day has made no difference at all

my lowest day of the week since starting is is my weigh day Sunday (I’m 27 weeks in)
I gain Monday to Wednesday
then stable Wednesday to Friday
I loose from Friday to Sunday (if I loose from Wednesday I loose more, but only happened 3 times )

diet more or less the same throughout the week

RedPony1 · 22/09/2025 13:32

I'm more idulgent Mon-Fri so i inject on a Sunday eve.
I'm always on my feet all weekend so no time to think about snacking etc, which means i'm busy and distracted when the dosage is wearing off

NikkiPotnick · 22/09/2025 13:41

I deliberately do mine on Mondays so my suppression is lowest at weekend, as that's when we tend to do things like have family celebrations and I do want to still be able to eat at those. In my case, the fact that I came in with BMI about 31, ie at the lower end of eligibility, probably is relevant there- wouldn't necessarily recommend it for everyone. There are good reasons why some people might want to time max suppression for their time off work, and it sounds like you may be one of them OP.

In terms of whether you'll experience any side effects and what point in the week. I think you just have to try it and see. Remember there's nothing stopping you moving the day if it doesn't work for you.

OnceIn · 22/09/2025 13:43

I started injecting at night time before bed so I could sleep through the start of any side effects. I also did it on a Friday night for the same reason, so I was at home in the weekend and not having to deal with side effects at work.

that said I know what to expect now, so tend to inject on a Saturday morning

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