When do the side effects from increased dose affect you?

[Inyournewdress]

I was wondering…if you get side effects or worsening of them when increasing a dose, what is the timing of them? Do you find it’s usually within a few hours of the jab or a couple of days etc? Or random!

I am going up to 5mg sometime between today and Tuesday…just anxious about the school run 😬

Are you going up from 2.5 to 5? I spent 4 weeks at 3.75 (45clicks) before going up to 5 and it seemed to minimise them a fair bit...

I would like to do that I think @Sam, I think. Do you mean 45 turns of the pen?

Yeah, you just count the clicks. 45 clicks on a 5mg pen is 3.75mg

24-48 hours after are generally the worst for me.

I agree that it's wise to do 3.75 first as it helps to minimise the side effects.

I was incredibly poorly 48 hours after going up to 5 and I really regret it. I would definitely recommend the 45 clicks up to 3.75 for a few weeks. It will also save you money!

Thank you, I am going to do 3.75. Got to do something as 2.5 really not working, but a middle way for a month might help. I have a quite long walk to and from school pick up and there’s never a good time to do these things so any way to cushion the adjustment is good!

2.5 used to work but it’s really stopped doing so now.

I always do my jab just before im getting into bed. I found this to be quite helpful.

I also did 3.75 for a while, maybe 8 or 9 weeks. Otherwise it’s a big jump up

I’ve just gone up to 15mg from being on 12.5mg for 2 months and felt really sick yesterday. I could hardly move. Any ideas of what dose I could go to instead of the 15mg?

It made me very ill too, I just used the whole pen then dropped back down to 12.5, which wasn't the best idea as I was a zombie for a month, only eating 700-900 cals a day but I lost a lot of weight! but you could try clicks to 13.5 if you want an inbetween?

That’s what I’m like now. Feel sick, so tired, stomach feel off. Did you start feel better by the end of the pen? I’m thinking of 13.5mg but not sure how many clicks that is?

No I was ill upto the very end, exhausted every day but I've kinda felt like this since day 1 just got worse on higher doses but always been there and no enthusiasm or energy to do any jobs etc. I also took the bonus dose as an idiot, full amount must've been 17mg in there. And then it took a few weeks of dropping down before it started to feel better as the concentration in body builds. It's weird as 12.5 wore off which is why I went up but 15 was too strong throughout, I never got used to it.
It's 54 clicks for 13.5. 0.25 per click.
I'm now down to 10.5mg because I'm tapering down as even 12.5 was too strong then, I think because overall was concentration had built up too high in body.

I’ve been on it a year at the end of this month, and one thing I’ve learned is that 2.5mg is too much to add to usual dose. I have to go up by half a ml each week otherwise I am very ill.

@KitsyWitsy how exactly does that work with the pen, if you know what I mean?

I’ve always done them in the evening. Never had any side effects beyond a bit of constipation. I’ve been on it for 13 months and am about to take my first 15ml dose.

I am glad I didn’t go up to 5 mg. I did the 3.75 last night and am now up with a bit of an upset tummy and bit nauseous. I really hope this settles I have an event in the morning! Thanks so much for the advice as if I had gone up to 5 mg can only imagine would be worse!