Another calm and supportive thread to discuss the Price Increases: Mounjaro THREAD TWO

[TryingAgainAgainAgain]

Keep calm and carry on discussing The Pendemic…

(sorry)

Had anyone had success ordering from the Family Chemist? I had an email yesterday morning to say that strengths up to 7.5 were now in stock and that one pen would be able to order for existing customers. Which is very fair. However, ever since I've had an error message when trying to access their website!

Success! My prescriber emailed about 5pm yesterday to say they had 2.5-10 back in. Just got on their website now and 7.5/10 are already sold out. But I've got my low dose ordered to be shipped out on Tues for delivery Weds🤞

It’s interesting to see where Eli Lilly have obviously settled (allowing MMP to offer at £270), and with the wholesaler rebate being on the condition that the full saving is passed on to patients, you can tell which pharmacies are now using this to make a huge chunk of profit.

(very pleased about this as the less businesses that have hideous full length photos of me + my ID the better!)

Absolutely. Surely those pharmacies who are at the more expensive end of the market are now going to lose all their customer base though. (Once other pharmacies like MMP start taking on new patients) They have to remain competitive. Now more than ever.

For those following memegate on Circle, someone has now posted a fucking POLL asking people if they wish to see multiple memes daily.

What busy lives they must lead. God, I hate Memes with a passion and leave folk on 'unread' who send me them on WhatsApp.

@PresidentBarklett

😅 the comment from someone who obviously hasn't a clue about what's been going on 'Lovely idea'. Aww bless.

I hate them too, but I do think they're being a bit mean to somebody who is harmless if potentially a bit hard of thinking.

Great entertainment though, to be fair. I'm ashamed to say I'm loving the whole thing. My favourite are the people wailing 'be kind!'.

No success. They are dreadful! As a customer of almost 12 months I was really annoyed when they sold all their pens to just anyone after the announcement and didn’t protect existing customers. I was on 10mg and couldn’t get a pen from them. No stock of high doses till September now. Unless they are cheapest or no one else will sell to me - I am BMI c24-25 now so almost maintenance - I won’t be giving them my custom again.

Someone said yesterday they tried to order 40 minutes after getting that email about lower dose pens and either the doses were sold by the time they finished their consult or the website wasn’t working.

Medicine Marketplace were consistently lower priced before this. No faffing with codes etc either.

Oh. My. God. Saturday morning entertainment sorted, even though I have a bloody parcel to drop off

I’m quite glad I have a couple of pens and a holiday lined up. It’s going to be absolute carnage, unless places like medexpress are going to restart their discount codes.

There is a problem though MMP are relatively small based on their previous stock allocations they likely supply around 10,000- 15,000 people per month. There are 1.5 million people taking WLI, MedExpress and Pharmacy2U supply hundreds of thousands of people per month. They know the small pharmacies offering 15mg pens sub £300 can't possibly supply everyone, thus people will still have to buy from them. The big guns really only have to complete with each other. I think we'll have a better overall picture once Pharmacy2U, Simple Online Pharmacy and IQ doctor declare their prices.

Not necessarily. I went back to Asda and paid a bit more because of the ability to go in person. And they just felt better, more professional.

I’ll be the same after. Unless Asda prices are completely prohibitive then I will stick with them and pay a bit more. Same reason people went with Boots or Juniper to start with I suppose.

I highly recommend a book called “Why diets make us fat” by Susan Aamoht. She also did a TED talk on it. It explains why we give up on diets, the evolutionary and genetic elements of weight etc.

https://www.ted.com/talks/sandra_aamodt_why_dieting_doesn_t_usually_work

I think this was often the advice widely quoted in the beginning. Partly because the safety trials put people onto the higher doses to see if they could tolerate them, and partly due to misunderstanding about what initial loading doses meant. MJ has a half-life of around 5 days in most people and so it takes time to build up to a level where it works effectively, but once people reach that level, there is no requirement to race up through the doses and a higher dose doesn’t mean more effective.

People need to find a level that meets their suppression needs without too many side effects. Within the extremes of nausea and not eating vs no side effects but no dietary changes there is personal choice too. Some people will choose a lower level of suppression so that they are still exercising willpower and control, others may choose to tolerate a higher level of side effects.

For most people who are losing weight on their current dose and tolerating the side effects, there is no need to increase the dose and If the side effects are too much, the advice is to reduce the dose. OTOH if there is no side effects and limited suppression, it is probably worth trying a higher dose.

We know that long term success comes from long term changes and I think (and I say this hypocritically as someone who is panicking if their next pen will turn up) that holding our nerves if we can, is the best plan. Steady progress is what we should be aiming for and we need to trust the process.

This obviously relates to diets before MJ! MJ actually works on the hormones she talks about which is why it works. If we can use MJ to change our at point weight we can maintain it.

The guidance still remains that if you’re using the half doses for more than a month (2.5, 7.5, 12.5), you’re using it off label.

for me I’ve done all sorts. I spent some time at 6.25, jumped back and forth between 7.5 and 10mg, split dosing. But the official guidance doesn’t seem to have changed.

Can I ask where that guidance is from @ThatCyanSheep? It is widely quoted, even by HCP but isn’t what the licence says. I’d be interested to bottom it out.
(posting link incase screenshot is delayed).
https://www.medicines.org.uk/emc/product/15482/smpc

That’s just what I’ve been told by all three of my prescribing pharmacies, I know even on places like Reddit you’ll talk about splitting doses etc and get a lot of stick!

Argh, my cloud order has been cancelled, and oushk order hasn't turned up. It should have arrived yesterday but the tracking info still says "we're expecting your parcel".

No deliveries now until Tuesday so the cold chain will be broken

I have tried a curate order but they need a video call before approving (which I have booked for the first available date). I have no confidence that the order won't be cancelled like cloud.

Thanks to everyone who replied to me and explained, I was feeling really stupid!
I will try and order my next pen with Voy after my 5mg comes on Tues.
What’s hard when you’re quite new to it is guessing if you will need to move up or not as a lot of people have been discussing.
2.5 hasn’t done loads for me apart from helping me focus on the way ahead so I’m thinking 5mg will give me the better suppression I need. But it’s tricky to know whether to order an extra 5 from somewhere whilst getting the next 7.5 from Voy. I know I can store them for future titration down but almost seems not worth it for us newbies.

Is it Royal Mail? Round here DPD still deliver on Sundays and bank holidays.

I’ve had MJ delivered by Royal Mail on a Sunday before! Considering they can’t deliver post most weeks around here, I was astounded!