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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Very high suppression

3 replies

Marylou2 · 09/08/2025 14:19

For context I've been on Mounjaro for 6 months. 2 months on 2.5mg and 4 months on 5mg. It's worked so well and I haven't needed to increase the dose further. I'm 5lbs off my target weight and took the final/4th dose from a 5mg pen on Thursday evening. Given that I've been on this dose for months and there's no scope for wrong dose or amount it has hit me so hard. Taken all morning to eat one yoghurt. I've been so careful all the way through with protein, exercise and electrolytes. Haven't changed my injection site . I always cycle around the abdominal area. Was going to go back down to 2.5mg for maintenance after the next pen but wondered if anyone else had experienced this after several months on Mounjaro. Think it's definitely suppression rather than just feeling ill. Thanks for any insights.

OP posts:
Bipaloss · 09/08/2025 14:40

Marylou2 · 09/08/2025 14:19

For context I've been on Mounjaro for 6 months. 2 months on 2.5mg and 4 months on 5mg. It's worked so well and I haven't needed to increase the dose further. I'm 5lbs off my target weight and took the final/4th dose from a 5mg pen on Thursday evening. Given that I've been on this dose for months and there's no scope for wrong dose or amount it has hit me so hard. Taken all morning to eat one yoghurt. I've been so careful all the way through with protein, exercise and electrolytes. Haven't changed my injection site . I always cycle around the abdominal area. Was going to go back down to 2.5mg for maintenance after the next pen but wondered if anyone else had experienced this after several months on Mounjaro. Think it's definitely suppression rather than just feeling ill. Thanks for any insights.

Great work on nearing goal. Could it be the injection site? I’m 5 months in but on my second pen of 10mg . I only inject in tummy but have more suppression lower right and upper left vs upper right and bottom left , noticed this on my last dose of 7.5 mg that I suddenly had more suppression especially on upper left and have done that site twice after and deffo more suppression .

Wishe · 09/08/2025 15:36

Suppression is a side effect and like all side effects on Mounjaro it can come and go, increase or decrease, with no rhyme or reason.

I wouldn't worry about it or overthink it right now. Try and hit your nutrition goals but if you can't today you can always eat a bit extra tomorrow so your weekly goal is still achieved.

Marylou2 · 09/08/2025 16:43

Thanks for the responses. Yes it could be the injection site. It was a surprise to suddenly have such high suppression after all this time. I've noted it on my shotsy app and will avoid in future. So interesting that a few cms can make such a difference. Absolutely will make up for any lost calories and protein later in the week!!

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