I have 8 stone to lose. I have been taking it for 5 weeks - just had my first 5mg dose this week.
So far I have only lost 2kg, which is frustrating given that it definitely has suppressed my appetite right from the start. However, I am aware that the first 2.5 dose may not have any effect.
The side effects have been mixed. I did feel sick and have diarrhoea in the first few weeks, although the nausea seems to have passed - I still get diarrhoea but I've always suffered from that anyway.
The biggest issue I've had is mental.. about 10 days ago I started getting extremely anxious, and essentially in constant flight or fight mode. I want to pace around like a caged tiger, and it almost feels like there's something inside the back of my brain I want to rip out. Last week was very unpleasant. It seemed to recede over the weekend but came back yesterday (24 hours after my next dose, but also my first day back at work for 3 days), although not as severe.
I am very bad at keeping myself hydrated at the best of times, and that is no doubt that I have probably made myself dehydrated especially with all of the diarrhoea, so it may not be the medicine itself but that I've got my body out of whack. I'm going to try to get hydrated and take some electrolyte powder and see if that will help. I want to continue as clearly with 8 stone to lose the rewards will hopefully outweigh the risks... but if this fight or flight mode continues I will sadly have to stop I think.
I'm certainly not trying to put you off, I think it's absolutely worth trying it! But just be prepared for the side effects and don't let yourself get dehydrated!