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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

June 2025 Starters - Mounjaro (thread 4)

1000 replies

FoxRedPuppy · 10/07/2025 18:27

Into our second month now!

OP posts:
Thread gallery
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ChiaraMontague · 12/07/2025 17:16

W5D1 - I did my first 5mg jab last night. Feeling ok so far. I had a breakfast smoothie and a coffee about 10.30 and not felt hungry for anything else yet but that might be because it’s so hot today!

Ive had about 2.5 litres of water so far and still sipping

MissMogs · 12/07/2025 19:16

Just wondering if this is normal. New 5mg pen. Clicked a couple of times for priming, but nothing came out when I pushed the plunger down. Had to do it about 3 times before any liquid came out (as in clicked again). Also when I did my actual dose, the plunger was sort of stiff to push in. Not good when you’re trying to hold the needle steady! Dodgy pen or normal? My last one (2.5) was very smooth!

healthjourney · 12/07/2025 19:30

@MissMogs I had this with the first dose from both my pens so far. The first dose took 3 attempts at priming then all the other doses were fine with just the 1, so I'd say nothing to worry about but if it doesn't seem right at your next dose you could speak to your provider.

MissMogs · 12/07/2025 19:34

healthjourney · 12/07/2025 19:30

@MissMogs I had this with the first dose from both my pens so far. The first dose took 3 attempts at priming then all the other doses were fine with just the 1, so I'd say nothing to worry about but if it doesn't seem right at your next dose you could speak to your provider.

Thank you for sharing! Were yours stiff to push in to administer the main dose as well? It made me feel like I was going to waggle the needle around and cause bruising because it wasn’t sliding in smoothly. Also what if it runs out of clicks because I’ve used too many priming it excessively?!

healthjourney · 12/07/2025 19:38

@MissMogs a little bit, to be honest I'm always a bit nervous pushing it down and doing it so slowly so not sure I'm a good judge or whether it is smooth/stiff! I think there are normally some extra clicks in a pen over the 240 needed for 4 doses so unless you need to prime more than 3 times every dose it should all still add up OK.

Gingercar · 12/07/2025 20:07

FoxRedPuppy · 12/07/2025 11:59

I meant to get up early today and go for a run, but I didn’t 😂

W4D6. I’ve lost 7.1lg now. I’m so unsure about 2.5 or 5 on Monday. I drinking noticed less suppression and a bit more hunger this week. But not to the point I over ate. And I’ve lost quite quickly, which I don’t love. I was so certain I was moving to 5mg and now I don’t know!

Especially as my side effects have pretty much gone.

Why don’t you try a 3.75 first? Then 5 next week if all goes well?

Tinybirdie · 13/07/2025 03:45

W7 D2
Still only taking 2.5mg. Been on holiday and still managed a small loss. Suppression has definitely waned so am contemplating 3.75mg next week. Bowel issues are my one side effect. Sometimes constipated and then a day of diarrhoea!

Sw 13 stone 8
CW 12 stone 7
GW 10 stone

ShesRunningOutTheDoor · 13/07/2025 08:54

I’m on 2nd pen. 3.33mg. Good suppression. Eating in calorie deficit. Have done 3 ‘bootcamps’ this week and scale not budged at all. Hope it’s a short-lived plateau. Lost a stone in first 5 weeks

FoxRedPuppy · 13/07/2025 09:09

ShesRunningOutTheDoor · 13/07/2025 08:54

I’m on 2nd pen. 3.33mg. Good suppression. Eating in calorie deficit. Have done 3 ‘bootcamps’ this week and scale not budged at all. Hope it’s a short-lived plateau. Lost a stone in first 5 weeks

I’ve read a few people plateau after the first few weeks as your body gets used to the new eating etc.

OP posts:
FoxRedPuppy · 13/07/2025 09:11

@Gingercar i definitely should just try 3.75. Dunno why I’m dithering about it!

I definitely felt hungry in the late evenings, but that could be the heat and a bit of dehydration. And also think that’s ok, as I will probably need to get used to that.

OP posts:
UglyBastardFace · 13/07/2025 09:18

ShesRunningOutTheDoor · 13/07/2025 08:54

I’m on 2nd pen. 3.33mg. Good suppression. Eating in calorie deficit. Have done 3 ‘bootcamps’ this week and scale not budged at all. Hope it’s a short-lived plateau. Lost a stone in first 5 weeks

I am having a similar experience. Lost a stone in the first 4 weeks. Now on 3.75mg, last week I gained a pound. 😯

I am in calorie deficit and logging everything I eat but am exercising and weight training. I'm thinking muscle is denser than fat so maybe this may account for the slight fluctuations.

Oldlady62 · 13/07/2025 09:19

UglyBastardFace · 13/07/2025 09:18

I am having a similar experience. Lost a stone in the first 4 weeks. Now on 3.75mg, last week I gained a pound. 😯

I am in calorie deficit and logging everything I eat but am exercising and weight training. I'm thinking muscle is denser than fat so maybe this may account for the slight fluctuations.

Edited

Try going up to 5 it's more of a therapeutic dose xx

SomethingAboutYou · 13/07/2025 09:25

The last couple of days I've been weighing daily and I've dropped a pound since official weigh day on friday! It's as if the 2.5mg is showing off now that a 5mg is on its way!! Or could be the tonnes of water I'm drinking thanks to the heat!!

Huge non scale victory (NSV) - I can comfortably lean over my knees and touch my toes to cut and paint them 🎉 my belly used to be in the way and I'd need to come up to breathe and lean round the side of my shins awkwardly. I'm not even a full stone down yet and I can't believe how much my belly has deflated, bloody delighted! (I'm W7D2)

SomethingAboutYou · 13/07/2025 09:28

I would say losing a stone in 4 weeks is quite fast so your body is probably just balancing out and will cary on losing when it's adjusted. A little rest for a week makes sense to me. Consistency is our friend so don't go making major changes to your calorie intake etc it was obviously working!

ToddlerMumma · 13/07/2025 09:45

Checking in at W6D6 and 11lbs down. Weight loss has slowed but 1-2lbs a week will do me. I thought appetite suppression was not working as well but went out for dinner last night and totally couldn’t eat much so they let me take it home! If I eat too much, I feel horribly full and uncomfortable for ages

ShesRunningOutTheDoor · 13/07/2025 09:52

UglyBastardFace · 13/07/2025 09:18

I am having a similar experience. Lost a stone in the first 4 weeks. Now on 3.75mg, last week I gained a pound. 😯

I am in calorie deficit and logging everything I eat but am exercising and weight training. I'm thinking muscle is denser than fat so maybe this may account for the slight fluctuations.

Edited

I am hoping this is the case too. Also water retention and inflammation in muscles from exercise causing scales to stay still. If I am losing fat and building muscle - great. If I’m not 🥲

MissMogs · 13/07/2025 11:00

Good news today - after a small gain yesterday (99.1 to 99.3kg), this morning I went down to 98.4!

Not so good news - nausea has hit after moving up to 3.75mg for the first time yesterday! Hoping it stays just as nausea…
Also had a nosebleed this morning

RatherTardy · 13/07/2025 11:13

BoredReceptionist · 12/07/2025 13:56

Third time lucky with this, I put it on thread 3, then started a thread 4 having missed this one!!

7th injection this morning, 6th weigh in. I’ve stayed with 2.5 as the suppression is really good still. I’ve lost a total of 1st 3lbs. Starting weight 15st1, current weight 13st 12 (goal probably 10st 7 ish). I’m over the moon to be honest, it’s such a relief to finally find something that works! I’m exercising, drinking loads of water, eating sensibly with occasional treats and I think I’ve been incredibly lucky with next to no side effects. My pens have come from Medexpress and then IQDoctor to use discounts I’d found, but I plan to switch to Lotus I think as they guarantee a maintenance plan for when I reach target.
Randomly, I’ve started getting news articles in my facebook feed featuring PTs moaning that people are using MJ as a quick fix. Idiots!!

We're very similar.

I started 1lb less than you, and I've not lost quite as much. But I'm v pleased with my weightloss

RatherTardy · 13/07/2025 11:16

I've STILL not heard from Pharmacy2U

I've emailed them directly

Thank god I did the golden dose. But I'm going to need to jab on Wednesday

healthjourney · 13/07/2025 11:20

Morning June Jabbers!
SW 14st 2
CW 12st 13.5
GW 10st 7ish

Another 2lbs off for me this week which means I am in a new scale bracket, a number I haven't seen in around 5 years 🥳 plus I found a pair of shorts and some PJs in my 'too small' clothes box that now fit perfectly. I hope you are all having a good weekend with some scale or non-scale victories too.

Focusispower · 13/07/2025 11:24

It is interesting to hear how people’s weightloss is showing up across their bodies. My tummy has massively gone down and my waist is back! I had really painful boobs for about a week and then they have deflated somewhat! I don’t mind as I was sick of having bigger boobs having breastfed or been pregnant for a solid 6.5 years. I would like my thighs and my knees to shrink next!

I think this last week of my first pen is going to see a plateau but I did lose a lot in the first three weeks. Still sticking to 2.5mg though. I’ve only had side effects after eating something unhealthy so it’s massively incentivized me to stick to healthy choices. My worst side effect seems to be not sleeping but that could be peri or heat or all three!

I had a couple of drinks on Friday night and felt really sick - couldn’t finish the second one! I hadn’t really had anything to drink since starting and I’m not sure I will go there again in a hurry!

Gingercar · 13/07/2025 11:24

RatherTardy · 13/07/2025 11:16

I've STILL not heard from Pharmacy2U

I've emailed them directly

Thank god I did the golden dose. But I'm going to need to jab on Wednesday

That’s awful. Have they had your money?

Thornrose · 13/07/2025 11:26

I met a friend today who I haven't seen since pre Mounjaro.

She noticed straight away that I've lost weight and asked direct if I'm on weight loss drugs. I confessed and it was almost a relief to share with someone in real life.

Unfortunately Sunday morning is my worst day after jabbing on Saturday. I always get dizzy and light headed.

I might jab on Saturday morning early instead of in the afternoon. I'm sick of my Sunday mornings being spoiled!

Thornrose · 13/07/2025 11:27

Duplicate post...

Crinklecat · 13/07/2025 11:50

Final weigh in after 4 weeks, doing the golden dose tonight. I’ve been away at a festival all weekend and I’ve gained 4lb in a day 😂 I did eat and drink lots but I think most of the weight is swelling in my legs and ankles from hours of dancing in this heat. Hoping it goes down quickly. I’m taking yesterday’s weight instead. So 1 stone 4 lb lost in 4 weeks. Doing the golden dose tonight and then will start the 5mg pen next week

June 2025 Starters - Mounjaro (thread 4)
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