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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Advice on what dose for 2nd pen

12 replies

YepIChangedMyNameForThis · 22/06/2025 08:38

On starter 2.5, have taken 3rd dose.
2nd week didn't feel as effective as the first week but this week (3) feels like week 1 again - appetite suppressed and avoidance of fatty foods - eurgh, just thinking of it is pretty horrific 😂 I have low level nausea and can pretty much cope with it but I find the tiredness pretty difficult.

Can I have some honest recollections of month 2 please? If you stepped up a dose did the SE increase? If you were tired on 2.5 did that get worse, did nausea turn to vomiting?

I have an event early August I would love a decent weight loss for and an operation on my ankle incoming, weight loss will help recovery. So the next month is quite key and I really do want a decent loss in July. If the second month felt like week 2 I would be gutted, it really didn't feel like it worked last week (although this week is fine).

What would you do?

OP posts:
loobyloo1979 · 22/06/2025 08:42

are you losing weight?

Histoscientist · 22/06/2025 09:07

Honestly with all those plans I'd go up. 2.5mg only lasted 2 weeks for me. 5mg lasted 5 weeks for me. I'm on 12.5mg and had zero side effects throughout other than just feeling cold and tiredness and no motivation to do anything which does get worse on every dose and is due to disruption of dopamine pathway and low calories. Started taking L tyrosine which converts to dopamine 3 weeks ago and back to positive happy smiling and more energy. Wish if found it 8 months ago.

Rose789 · 22/06/2025 09:16

The 5mg and 2.5mg pen is the same price so I would order the 5. If 2.5mg is still working just use 30 clicks of the pen to do a 2.5 dose but it means you have the option of going up without needing to wait a full 4/5 weeks before a new pen.

YepIChangedMyNameForThis · 22/06/2025 09:20

loobyloo1979 · 22/06/2025 08:42

are you losing weight?

First week 4
Second week put a pound on
This week definitely losing

OP posts:
YepIChangedMyNameForThis · 22/06/2025 09:20

Rose789 · 22/06/2025 09:16

The 5mg and 2.5mg pen is the same price so I would order the 5. If 2.5mg is still working just use 30 clicks of the pen to do a 2.5 dose but it means you have the option of going up without needing to wait a full 4/5 weeks before a new pen.

That is a really good suggestion, thank you

OP posts:
YepIChangedMyNameForThis · 22/06/2025 09:22

@Histoscientist I will look into that supplement, thank you. I do need to focus on supplements.

OP posts:
Histoscientist · 22/06/2025 09:22

Rose789 · 22/06/2025 09:16

The 5mg and 2.5mg pen is the same price so I would order the 5. If 2.5mg is still working just use 30 clicks of the pen to do a 2.5 dose but it means you have the option of going up without needing to wait a full 4/5 weeks before a new pen.

Yes I've done this with the 7.5mg pen and currently with 15mg pen, counted clicks and reduced doses as the higher one was too high and I could barely eat. Then eventually tolerance builds and I can go on to it fully.

creekyjohn · 22/06/2025 13:08

I have been on 2.5mg for 7 months. It’s not as effective as it was at the start but it’s still helping me lose a pound or 2 each week.

NicPapr25 · 23/06/2025 15:07

Hi, in month 2, had 5mg pen, but only did 40-45 clicks, so 3-3.5mg, just going into month 3 and staying on 5mg pen, going up to 4mg as getting good suppression and losing 1-2kgs per week, no real side effects, head ache day 2. I do take my jabs every 6 days as I find the suppression really reduces by then. Good luck, hope you find what works for you

Herewegoagainandagainandagain · 23/06/2025 15:24

@NicPapr25 Just an FYI for you and others who may see this as accuracy when sharing adjusted prescription doses is important: 40 - 45 clicks on a 5mg pen actually delivers 3.33mg - 3.75mg.

Did your provider suggest dosing more frequently than the usual 7 day schedule on a regular basis? Typically, that approach is only recommended very short term - usually just to finish a pen before moving up to a higher dose.

YepIChangedMyNameForThis · 23/06/2025 19:04

Daft question alert - will I find a you tube video to show me how to do part dose?

OP posts:
Histoscientist · 23/06/2025 20:52

You literally count them starting from 0, it's easier than you might think. Take your time and don't rush. I'm doing 52 clicks so going back from a full 60 turn as its quicker and easier going down 8 than counting 52!

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