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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weight loss trajectory in first month?

2 replies

Sweetysatsuma · 16/06/2025 11:33

Hi fellow June Jabbers,

Does anyone know what the typical weight loss trajectory is during the 1st month? I appreciate that there are differences but I'm on W1 D3 and have already lost 2 pounds. I'm consuming about 1000 calories per day. Not on purpose - it's all I feel like eating. I'm making sure I'm getting enough protein and trying to drink 2 liters of water.

I wonder whether the loss to date is more water than anything else.

OP posts:
SilenceInside · 16/06/2025 12:04

I don't think there is a "typical" as individual experiences vary a lot. The clinical trials showed that weight loss was not significant on average, whilst on the 2.5mg dose. Prescribers will say to expect 1 to 2 pounds a week, whilst also pointing out that not everyone loses on the initial dose level.

If you have a lot of weight to lose then you are able to create a larger calorie deficit at the beginning compared to someone who is at a much lower BMI. If your TDEE is 2,500 calories for example, then you could be in a 1,500 deficit every day and so lose at least 3lbs a week or more at the start.

Mounjaro also seems to reduce inflammation for some, I certainly had a quick reduction in lower leg swelling that I used to get which I am sure contributed to my high losses at the start.

WeAllHaveWings · 16/06/2025 13:27

@SilenceInside is absolutely right, I started with a BMI 44.8, so my loses although fairly similar to some others I chat with in the >5st thread who started with the same BMI as me, would be very different from someone starting with a BMI of 30.

If you are starting with a morbidly obese BMI > 40 I can share my first few weeks loses if you like?

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