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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Gone up 15mg Zero suppression this week.

4 replies

Oneeata · 06/06/2025 10:22

I've had my first 15mg on Monday and I have had absolutely no suppression whatsoever, I've been absolutely hank marvin and been back and forth to the fridge/cupboards like you wouldn't believe. I've gone over my calories slightly Tues/Wed/Thurs for the first time in weeks, hit my macros and had an extra protein shake yesterday and I am seriously hungry this morning. I have not felt any satiety at all this week.
Anyone had similar?

OP posts:
Belindabelle · 06/06/2025 10:35

Yes!

I am on my 2nd 15mg pen. Some days/weeks I have goodish suppression and some days I could chew my arm off. No rhyme nor reason to it that I can figure out. I always go for protein when hungry, avoid upf, loads of water etc.

I have gone up every month except for 5 when I accidentally ordered second pen and 12.5 when I wanted to delay taking 15mg because where do we go from here?

NaturalBlondeYeahRight · 06/06/2025 10:36

Yes I have, I put it down to trying the thigh instead of stomach but actually I wonder if we all just have weeks on mj when we are particularly hungry, especially as our bodies become ‘used’ to it. I’ve just broken out of a 9 week stall this week and I haven’t done anything different, just had more suppression this week on the 15 than the first week. I’ve got less to lose now as well so I think my body is adjusting to a new weight/set point theory and all that.

IsItSnowing · 06/06/2025 13:44

I am still on 10mg but I get days like this. Then I'll hardly want to eat for days. Then starving again.
I'm seriously considering going up to 12.5mg but not sure if that is the answer. I had similar on 7.5mg and so went up to 10mg but not much has changed really.
I'm reluctant to go up for 2 reasons, firstly there seems to be a shortage of the higher doses and secondly like you say, where do I go after that if I'm on the top dose/

Histoscientist · 07/06/2025 20:28

Stress and poor sleep can also affect hunger and suppression, as well as pmt or time of month. I know when I'm stressed and slept poorly, I crave carbs and chocolate (monday just gone) even if I've gone weeks/months without it before.
I'm on 12.5mg, found 15mg way too strong with suppression and affecting my energy leaving me flat and weary, so I dropped to 12.5mg. It disrupts dopamine and has always affected me from the start.

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