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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Anyone microdosing mounjaro?

99 replies

Fluffypiece · 06/06/2025 07:43

I am! W1 D3. Doing 0.5 for 2 weeks moving to 1.0 for the next 2 weeks and then will review with dr

so far mild effects but a reduction in hip pain that has plagued me for years - don’t know if that’s just psychological. No SE

(I know some people feel strongly anti re microdosing - I’m doing it with a dr and I’m happy with my choice - not advocating it for anyone else just would like to connect with anyone doing the same)

OP posts:
Amethystanddiamonds · 08/06/2025 19:20

The medication will probably be fine in the pen after 30 days but we don't know unless Eli Lilly have released the stability data (and I can't be bothered to look). Some medications can degrade in contact with air. The main risk though is infection. Bacteria will begin to grow in the pen once it is no longer sterile. Injecting bacteria under the skin is very rarely a sensible idea.

I also have no time with microdosing. Medications go through a hugely expensive and time consuming process in accordance with a raft of clinical trial regulations and all the paperwork and legalities it involves to find a therapeutic dose. They will have carefully balanced the therapeutic dose with the side effect profile and justified that dose and the risk benefit ratio to the regulatory authorities. Then someone comes along and says nope a tiny dose is absolutely fine?

WeAllHaveWings · 08/06/2025 19:27

summersleftus · 08/06/2025 19:13

The only advice I would give to anyone is do your own research , there is plenty of advice out there stating the biggest risk to using beyond 30 days is lessened efficiency, and the other risks you refer to are for a very small amount of users -weigh up your options as if you didn’t and decided to microdose (which as far as I’m aware doctors don’t recommend but it’s a personal choice )you would be throwing away more pens than you’d use I did my research and am not taking any risks with others,

To give some credibility to your post can you share your “research” that comes from a credible, trustworthy source and not from your counterfeit not “Tirzepatide” supplier and not anecdotes from social media that shows clearly genuine Mounjaro prescribed in a UK kwikpen is safe to use well beyond 30 days after first use.

summersleftus · 08/06/2025 19:33

WeAllHaveWings · 08/06/2025 19:27

To give some credibility to your post can you share your “research” that comes from a credible, trustworthy source and not from your counterfeit not “Tirzepatide” supplier and not anecdotes from social media that shows clearly genuine Mounjaro prescribed in a UK kwikpen is safe to use well beyond 30 days after first use.

No I can’t as I don’t need to give my reply’s any credibility and really cba going through months worth of google searches and linking them, not sure about your fb anecdote though -I’d never get advice from there nor here tbh - as I have previously stated I’m not giving advice make your own choices and take your own risks and discuss the risks with your doctor/supplier

Thisshirtisonfire · 08/06/2025 19:35

Amethystanddiamonds · 08/06/2025 19:20

The medication will probably be fine in the pen after 30 days but we don't know unless Eli Lilly have released the stability data (and I can't be bothered to look). Some medications can degrade in contact with air. The main risk though is infection. Bacteria will begin to grow in the pen once it is no longer sterile. Injecting bacteria under the skin is very rarely a sensible idea.

I also have no time with microdosing. Medications go through a hugely expensive and time consuming process in accordance with a raft of clinical trial regulations and all the paperwork and legalities it involves to find a therapeutic dose. They will have carefully balanced the therapeutic dose with the side effect profile and justified that dose and the risk benefit ratio to the regulatory authorities. Then someone comes along and says nope a tiny dose is absolutely fine?

I literally couldn't eat on 2.5. People's bodies react differently. The therapeutic dose from the studies is based on averages not your individual needs.
People should do what works best for them.
It would be great if we could all do this under medical supervision on the NHS but we can't.
I had to micro dose because I couldn't deal with the lowest "therapeutic" dose.
And it worked for me. I've lost 5 stone.
Think I'd be dead if I went ul the doses like it tells you to. I was barely managing 500kals a day on 2.5ml!! And I was on 2.5ml for 3 months so it's not like I didn't give my body any time to try and get used to it.

wobblybrain · 08/06/2025 20:32

WalkingOnADreamm · 08/06/2025 18:01

2.5mg x6 = 15mg and then times that by 4 as there are 4 doses

Sorry, can you actually explain it? How much (or little) liquid would a person be taking

WalkingOnADreamm · 08/06/2025 21:06

wobblybrain · 08/06/2025 20:32

Sorry, can you actually explain it? How much (or little) liquid would a person be taking

I think it would be 10 clicks? As each full dose is 60 clicks. Not sure on the amount of liquid. My question was just hypothetical because surely no one actually does this and keeps one pen opened for this long

WeAllHaveWings · 08/06/2025 21:19

@summersleftusAmazing how no one can ever find any of their alleged extensive “research” that potentially high risk changes to dosing schedules and using expired medication are actually ok 🤣. They never bookmark anything, note down links to go back to and can’t even find in google again.

Did none of your extensive research tell you that fake “not Tirzepatide” is ridiculously dangerous? Not sure research is one of your strong points.

Yes, in the absence of any credible evidence I will and do make my own risk assessments and choices, I also like to highlight posts that are clearly baseless, irresponsible and potentially dangerous to others.

I’ll leave it there and hide the thread as post like that risk harm to others probably rile me too much. You have dug yourself a big enough hole. Have a good evening.

Oblomov25 · 08/06/2025 21:22

I'm still calling bullshit on this aswell. How fast do you think General medications go out of date. Ever eaten food a day past its sell by date which was totally ok? This pen lasts months. You think taking a golden dose at month end will kill you?

where are these links to the golden dose killing people please? I'd like to read. Genuinely interested, not just about mounjaro but any medication.

summersleftus · 08/06/2025 21:24

WeAllHaveWings · 08/06/2025 21:19

@summersleftusAmazing how no one can ever find any of their alleged extensive “research” that potentially high risk changes to dosing schedules and using expired medication are actually ok 🤣. They never bookmark anything, note down links to go back to and can’t even find in google again.

Did none of your extensive research tell you that fake “not Tirzepatide” is ridiculously dangerous? Not sure research is one of your strong points.

Yes, in the absence of any credible evidence I will and do make my own risk assessments and choices, I also like to highlight posts that are clearly baseless, irresponsible and potentially dangerous to others.

I’ll leave it there and hide the thread as post like that risk harm to others probably rile me too much. You have dug yourself a big enough hole. Have a good evening.

Edited

😂😂😂 not once did I say I couldn’t t find it -I did say I cba digging it out for some random on a chat forum - enjoy your evening and I’ll enjoy my big hole ( which is now much bigger now my arse is only a size 10 from my fake tirz , I’ll bid you good night and won’t be replying again , too busy cataloging the research I found in case someone I actually give a shit about wants to read it 😂

BunnyEaster · 09/06/2025 00:26

I have just gone up from 5mg to a new 7.5 pen. However I'm getting itchy rash at injection site which is irritating for five days. I feel constantly sick too. I'm going to just dose 5mg from this pen unless I get rid of these side effects so I might see how I feel about using the two extra 5mg doses I will have left. My pen lives in the fridge. Pita as last two pens have been via med express and delayed delivery. I can't risk reordering at my third dose to see if it settles down. This is about as sick as I can tolerate feeling right now. So I might be breaking the 30 day rule.

Fluffypiece · 09/06/2025 08:06

BunnyEaster · 09/06/2025 00:26

I have just gone up from 5mg to a new 7.5 pen. However I'm getting itchy rash at injection site which is irritating for five days. I feel constantly sick too. I'm going to just dose 5mg from this pen unless I get rid of these side effects so I might see how I feel about using the two extra 5mg doses I will have left. My pen lives in the fridge. Pita as last two pens have been via med express and delayed delivery. I can't risk reordering at my third dose to see if it settles down. This is about as sick as I can tolerate feeling right now. So I might be breaking the 30 day rule.

Poor you - hope reducing the dose makes you feel better - were you getting results at 5? Might be you don’t need to go up

OP posts:
WalkingOnADreamm · 09/06/2025 08:51

BunnyEaster · 09/06/2025 00:26

I have just gone up from 5mg to a new 7.5 pen. However I'm getting itchy rash at injection site which is irritating for five days. I feel constantly sick too. I'm going to just dose 5mg from this pen unless I get rid of these side effects so I might see how I feel about using the two extra 5mg doses I will have left. My pen lives in the fridge. Pita as last two pens have been via med express and delayed delivery. I can't risk reordering at my third dose to see if it settles down. This is about as sick as I can tolerate feeling right now. So I might be breaking the 30 day rule.

I’ve had horrific nausea and vomiting for about 2 months and couldn’t get out of bed at times so I take Cyclizine and it really does help. The sickness has calmed down which I never thought it would

wobblybrain · 09/06/2025 10:14

WalkingOnADreamm · 08/06/2025 21:06

I think it would be 10 clicks? As each full dose is 60 clicks. Not sure on the amount of liquid. My question was just hypothetical because surely no one actually does this and keeps one pen opened for this long

It’s wild that anyone would buy a pen and use it 24 times.

WalkingOnADreamm · 09/06/2025 11:49

wobblybrain · 09/06/2025 10:14

It’s wild that anyone would buy a pen and use it 24 times.

I don’t think they do. My question was about people going beyond the 30 days. So when does it stop? Where is their cut off point?

Geordielass78 · 17/08/2025 20:40

I’m microdosing….so far so good, moved to 1mg today, have pens with exact dose so no clicking.

Ive lost 2-3lb in two weeks, being very mindful of keeping up strength training, getting enough protein and paying attention to drinking enough water, and asking myself if I’m really hungry…tbh I’m loving it, still enjoying food and drinks, but not snacking and eating smaller portions…all the things I should do, now I can do without overthinking xx

hope it’s working for you OP! X

onlymethen · 17/08/2025 23:26

I’ve micro dosed, used the same pen for3 months, a risk I’m happy to take. And for anyone asking about it’s effectiveness, I’ve not lost weight since reaching my target but have maintained.

babylone · 18/08/2025 11:24

@onlymethen can i ask how many jabs you have done over the course of three months using the same pen? I am interested but worry about damaging the seal with repeated “perforations”/jabs. Thank you I am also happy using it for longer than intended

TheRealGoose · 18/08/2025 11:36

wobblybrain · 09/06/2025 10:14

It’s wild that anyone would buy a pen and use it 24 times.

the pens are self sealing, they reclose, so it isn’t like piercing a normal piece of material, and they are tested with hundreds of piercings, if there was a risk there would be huge warnings on the box and on the leaflet, and el Lilly don’t say it’s not fine, they just say they can’t guarantee it. Which is very careful wording, they don’t want to encourage people as it impacts their profits.

wobblybrain · 18/08/2025 11:41

TheRealGoose · 18/08/2025 11:36

the pens are self sealing, they reclose, so it isn’t like piercing a normal piece of material, and they are tested with hundreds of piercings, if there was a risk there would be huge warnings on the box and on the leaflet, and el Lilly don’t say it’s not fine, they just say they can’t guarantee it. Which is very careful wording, they don’t want to encourage people as it impacts their profits.

I never mentioned anything about this

Fluffypiece · 18/08/2025 13:40

Good to hear @Geordielass78 and @onlymethen ! @onlymethen whatbdose are you using? And @Geordielass78 whats your plan for once you reach target? Has your clinic said anything about that? X

OP posts:
Geordielass78 · 18/08/2025 14:25

@Fluffypiece im getting married next year so if I can afford it would consider staying on a small dose til then, currently on 1mg so will see how that goes! Will talk to the clinic once I’m nearer target, taking it slowly so will be a few months xx

Fluffypiece · 18/08/2025 17:55

Ah congratulations @Geordielass78 ! Yes that had been my plan too but this finding re the risk to eyesight has made me think again. I was planning to maintain at 0.5 or 1mg partly for the other benefits to cognitive health etc …. In a quandary now!

OP posts:
babylone · 18/08/2025 17:57

@Fluffypiecewhat risk to eyesight?

Fluffypiece · 18/08/2025 18:08

babylone · 18/08/2025 17:57

@Fluffypiecewhat risk to eyesight?

There was quite a bit of coverage over the weekend. If you google you’ll see a few articles.

OP posts:
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