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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Anyone microdosing mounjaro?

99 replies

Fluffypiece · 06/06/2025 07:43

I am! W1 D3. Doing 0.5 for 2 weeks moving to 1.0 for the next 2 weeks and then will review with dr

so far mild effects but a reduction in hip pain that has plagued me for years - don’t know if that’s just psychological. No SE

(I know some people feel strongly anti re microdosing - I’m doing it with a dr and I’m happy with my choice - not advocating it for anyone else just would like to connect with anyone doing the same)

OP posts:
Glowingup · 06/06/2025 11:24

Loveautumnhatewinter · 06/06/2025 11:17

I read something somewhere yesterday that the ‘golden dose’ people are referring to has been linked to deaths. And that it wasn’t intended to be used. Don’t know the legitimacy of what I’d read, just thought I’d flag it.

That seems incredibly unlikely when you think about it. It is precisely the same liquid as the other doses in the pen. If you think about it logically why would 1/5 of liquid kill you but the other 4/5 is fine? It sounds like yet another moronic social media rumour. It’s up to the individual if they want to pay more for their medication than they would otherwise need to.

Divebar2021 · 06/06/2025 11:31

I’d love to know how a coroner would link a death to the use of the golden dose.Theres so much anti “ Ozempic” rhetoric online and in the media.

Anyway to the question … I’m a pound or so away from target so working my way back down from 10mg. Im
actually bought a 10mg pen last time because it was the same price as the 7.5. Im using syringes to extract so I’ll be going beyond the 30 days. I would definitely be interested in micro dosing as a maintenance strategy but at the moment I’m waiting to see how I feel as I go. I suspect it will be more feasible to start low and stay low than come down from a higher dose.

SilenceInside · 06/06/2025 11:31

@Loveautumnhatewinter there was a DM+ article behind a paywall about this yesterday, which was a load of scaremongering nonsense and inaccuracies. No mention of any actual cases of anyone experiencing any issues, let alone dying.

Glowingup · 06/06/2025 11:42

Yeah I mean the link between Mounjaro and deaths full stop is iffy as everyone who has died had comorbidities but it’s ludicrous to suggest that the link is to one specific dose out of the pen.
I think I read the article you’re talking about actually. Was it the Daily Mail? They didn’t say anything about dying from it and it was very vague but one thing mentioned was the risk of an overdose. Some people have messed up dosages with syringes including someone I saw on tiktok who said she had assumed she needed to take 2.5 ml to get 2.5 mg. So a giant overdose (although I don’t think she actually took it). But if you’re a reasonably intelligent person it’s not hard to extract it or work out the correct dose.

Fluffypiece · 06/06/2025 13:36

hedgerunner · 06/06/2025 07:51

I’m not micro dosing, but someone I follow in insta is and is having great results. How do you it as I thought pens can’t be used after 30 days.

Oh that’s interesting @hedgerunner - when you have amin can you post their handle - would be great to follow

OP posts:
Fluffypiece · 06/06/2025 13:38

Divebar2021 · 06/06/2025 11:31

I’d love to know how a coroner would link a death to the use of the golden dose.Theres so much anti “ Ozempic” rhetoric online and in the media.

Anyway to the question … I’m a pound or so away from target so working my way back down from 10mg. Im
actually bought a 10mg pen last time because it was the same price as the 7.5. Im using syringes to extract so I’ll be going beyond the 30 days. I would definitely be interested in micro dosing as a maintenance strategy but at the moment I’m waiting to see how I feel as I go. I suspect it will be more feasible to start low and stay low than come down from a higher dose.

That’s amazing ! Well done , must feel really good to be at this point

OP posts:
NormasArse · 06/06/2025 13:41

How does it stop pain?

Fluffypiece · 06/06/2025 13:43

onlymethen · 06/06/2025 09:27

I’ve name changed for this as I’m sure a bun fight will follow.
Ive been microdosing for 3 months from a 15mg pen. My prescriber knows and although she can’t advocate it for professional reasons she has directed me to lots of information on microdosing.
This wonder drug does so much more than just weight loss as trials coming through will soon show and it will benefit people in many ways that are just starting to be discovered.
as for throwing it away after 30 days, as long as you are using sterile needles and alcohol wipes the chance of infection is very low.

Thanks @onlymethen and @BerfyTigot - yeah I really don’t want to be fighting with anyone on this! My doc does the micro doses for me. Would be great to hear about your experience - I’m only 4 days in but really hoping to reduce inflammation and food noise …. If better I’d be so grateful if you could dm what it’s been like for you xx

OP posts:
Fluffypiece · 06/06/2025 13:48

That’s great to hear @lifetheuniverseandeverything42 - I think that swallowing thing might be silent acid redux (something I get) - yes I’m hoping to get enough of the anti inflammatory and appetite suppressant at a low dose - hopefully no more than 2

OP posts:
almostbloody50 · 06/06/2025 13:58

I’m just about to start microdosing to support chronic pain, I do need to loose a small amount of weight but that’s not why I’m taking it, I need to balance hormones and I’m curious to see if it reduces my endometriosis flare ups as it has a huge impact on inflammation, I’m willing to take the risks as it’s a tiny amount.

listen to this if you are interested in why it’s being used this way, I know it’s being used for pain relief for inflammation linked disease.

https://open.spotify.com/episode/5YmZRXRm7bzgk3F1IOBcFO?si=0w4E7cKMQ4iYUJIedsiDTw

BerfyTigot · 06/06/2025 14:00

I started microdosing because of the extreme side effects I suffered after the first dose (projectile vomiting and uncontrollable diarrhoea).

Week 2 I did 40 clicks of the pen and another 30 5 days later when the food noise restarted ( so not actually less but split dose. I still had SE on 40 clicks so that's why I reduced the next dose.

I waited a full week for the next dose of 1.25mg (30 clicks) again hoping for a few days without diarrhoea. I had moderate diarrhoea and nausea but again food noise kicked back in, so 4 days later I had the rest of the dose.

Then I started to get a bit more scientific about it and used Shotsy (free version) to work out how much was actually in my bloodstream. This week has been the first time that I haven't had side effects and it's been blissful 😁. I've taken 1.25 mg on Monday and am planning to take another 1.25 in a few days' time.

trickyex · 06/06/2025 17:39

I have just ordered my first pen and want to start off microdosing, to take things slowly and minimise any possible side effects, I dont always react well to new medication.
Could I ask where you order your extra needles from?

RelaxedOddish · 06/06/2025 18:04

That's interesting that you're micro dosing. I have seen that this is becoming popular in the US because of the other health benefits.

OP I take it you're not obese but your Dr supports you micro dosing for other benefits?

trickyex · 06/06/2025 18:10

@PearlsPearl thank you, will take a look.
Lots to take on board....

Fluffypiece · 06/06/2025 20:27

RelaxedOddish · 06/06/2025 18:04

That's interesting that you're micro dosing. I have seen that this is becoming popular in the US because of the other health benefits.

OP I take it you're not obese but your Dr supports you micro dosing for other benefits?

Yes that’s right. Not obese (but overweight), gerd, Asian (so 25 bmi for Asian person is considered 27 in a white person) - but mainly a lot of inflammatory pain - fingers crossed I’ll get some relief because the impact of the insomnia due to pain and gerd is really intolerable …. 😞

OP posts:
Itscoldouthere · 06/06/2025 21:20

@almostbloody50 thank you for posting that link, really interesting.
I’m now in maintenance and going down the doses, hoping to end up just taking a really small amount for general health benefits rather than just to control weight, so much scientific research happening with GLPs and new drugs coming in the future, all very interesting.

almostbloody50 · 06/06/2025 23:14

Itscoldouthere · 06/06/2025 21:20

@almostbloody50 thank you for posting that link, really interesting.
I’m now in maintenance and going down the doses, hoping to end up just taking a really small amount for general health benefits rather than just to control weight, so much scientific research happening with GLPs and new drugs coming in the future, all very interesting.

It’s fascinating, and her take challenges conventional drugs as well, if she’s is right people will be able to come off the statins, BP and diabetes drugs for life, if they micro dose could see some really radically changes for endometriosis and other conditions like PCOS and all inflammatory diseases. So along with the weight loss benefits it seems we could be looking at multiple benefits. And this is coming in pill form in 2026 but I’m yet to read any papers on that.

Ozgirl76 · 07/06/2025 02:55

The Daily Mail seems dead against any WLI - I guess it goes against their boomer readership which is women who have spent their lifetime with eating disorders “oh I couldn’t possibly manage a whole potato” and now are annoyed that the younger generation don’t have to do this.

Luckily all their scaremonger articles are behind a paywall these days so I’m not even tempted to read them!

Even The Times has a piece this weekend about coping with all the side effects like muscle loss - saying this can be “catastrophic” in middle age 🙄 as if those of us on WLI don’t know that we might lose some muscle as well as fat. I’m all for informing about weight training, bone density etc but for most people taking these medicines, the risk of staying overweight far outweighs (sorry) that of taking the drug.

Oblomov25 · 07/06/2025 04:49

What are the medical grounds against micro-dosing?
I can see the medical industry objecting, because they lose money if you make a dose stretch over say 2 weeks.

Ozgirl76 · 07/06/2025 11:43

Given that it seems like half the population is either on it or wants to be on it, you wouldn’t think they would be overly concerned about the money!

GeraniumRoseblush · 08/06/2025 11:33

So interesting to read this thread - I'm on my 6th week and fully expected to be taking at least 3.75 now but have just gone back down to 2.5 (after a golden dose of 2.9). 2.9 tipped me into not having any appetite and I didn't like that at all.

I realise 2.5 isnt a microdose but it's reassuring to hear that lower doses can still be therapeutic, and the additional benefits of reducing inflammation and relieving pain etc are huge positives. I have hip osteoarthritis so I'm keeping fingers crossed for improvements in the amount of pain there.

@almostbloody50 thanks so much for that link 👍 very interesting to watch

@BerfyTigot I read about your nightmare with SEs on the May starters thread so really great to hear your SEs have eased up on a microdose 🙌

summersleftus · 08/06/2025 16:32

Doggymummar · 06/06/2025 07:45

Your pen will time out won't it? You can only use for 30 days once opened.

Edited

If you leave it in the fridge it will last 6 months or more

Time4changeagain · 08/06/2025 16:41

summersleftus · 08/06/2025 16:32

If you leave it in the fridge it will last 6 months or more

@Doggymummar is right about the 30 days for a pen after first use. It clearly states this on storage instructions.

medical.lilly.com/uk/products/answers/how-should-the-mounjaro-tirzepatide-kwikpen-be-stored-217607

WalkingOnADreamm · 08/06/2025 17:35

After reading the comments I’m curious because if it’s safe and effective after 30 days then surely people would be buying the 15mg pen and using it for loads of smaller dosages? So if they wanted 2.5mg they could use the 15mg pen 24 times? Not judging I’m genuinely curious?

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