Do some people not feel any effects until they are on high doses?

[greatyak]

Asking for a friend (yes really!)

she has been titrating gradually on mounjaro through to her current 7.5 but so far has felt nothing at all. No negative effects and no reduction in appetite.

is this unusual? Does this suggest it won’t work on her at all or might she still feel something when she goes up to the highest doses?

7.5 is half way so I can't see it starting to work if it hasn't already

Last year i barely had any positive side effect all the way to 15mg ( and never had negative ones either). I was expecting it to do all the work for me though as it had done for my friends. I didnt lose much weight.

Ive recently started again calorie counting and taking responsibility and this time i actually think it does have an effect but i need to work with it too

@21ZIGGYso it just doesn’t work for some people? Strange isn’t it. She says it’s just like she’s not taken anything. It’s so peculiar as others feel horribly sick in the first dose and lose weight.

so why do you think you feel the effects this time?

Its annoying. One of my friends never moved off 2.5 as it worked so well. Everyone i know is thin now🤣

I dont think its effects are any different this time, i just think my mindset is (and having thin mates is a big motivator). Hopefully i stay on track.

It was 10mg or 6 months for me, I had lost three stone by then though so I was happy enough with that. I've been on 15mg since Christmas and have lost another three stone. Slower than most but I am 55 sedentary with underlying medical conditions.

From the research trials there’s about 10% of people who didn’t lose much weight. Some people also may need the 15mg to get the effects. Given that she’s half way through titration to 15mg I think I’d want to persevere through 10, 12.5 and 15mg to see if one of those was effective before deciding that it wasn’t working for me.

My friend thought 2.5mg was doing nothing for her as she said she didn't feel different. Until she told me she's noticed she doesn't snack between meals anymore, can't drink how she used to and she's a wine bottle on most nights type and said she's getting full up quicker like when she went out for a meal and ordered a cake with coffee but could only eat a few spoons of it! Sometimes it's working but until people think about it, they don't realise as they don't have any side effects.