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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Bad side effects - will reducing a dose help?

4 replies

Chinup100 · 20/03/2025 04:57

Week 5 day 5

Successfully completed 4 weeks of 2.5mg without any side effects and good suppression. Towards the end of the 4th week my blood sugars started to go up so I decided to increase to 5mg.

Injected 5mg Sunday morning. Monday I had sulphur burps all day and managed a slice of toast. Monday evening I threw up Sundays food, and spent all night on the toilet 💩
Since then I have felt really weak but managed little morsels of food.
Last night we went for a meal (birthday celebration) and I had 2 courses - soup and sea bass, I left about half of both courses. Since then I’m back on the toilet and have woken up at 4.30am with more diorrhea and feeling sick again. I am so done in!!

my question is: will going back down to 2.5mg help? I was considering 3.75mg but honestly I’m not sure I can bare it. I feel like shit!

OP posts:
Tradersinsnow · 20/03/2025 05:02

Yes dropping back to the 2.5 dose usually works. Going up to the 3.75 dose before the 5 dose is a good idea.

Good luck!

Phillister · 20/03/2025 06:30

I had similar symptoms on my second week of 2.5mg...in retrospect, I don't think I was drinking nearly enough water (I felt like I was but I think pre and post mounjaro water intake is incomparable!).and had eaten a small but quite greasy meal. I've not had reoccurrence since - things I think have helped - constantly staying hydrated, 3 or 4 peppermint tea per day as well as all the water, gaviscon on hand for the days after the injection avoiding grease and titrating up to 5 slowly.
Im 5 or 6 weeks off 2.5 and tonight will be my first 5. I think I did 3/3.5/4 and then very gently increased clicks from 4.
Good luck! Those couple of days were rotten for me but I'm personally glad I stuck with it.

shrinkingthiswinter · 20/03/2025 06:31

Yes! Go back down to 2.5. You can try 3.75 for a few weeks before going up to 5. I take 5 now but as two 2.5 doses.

stopringingme · 20/03/2025 06:33

@Chinup100

I had dreadful side effects with 5mg, vomiting, constipation etc.

I decided to stop for a week then I went back down to 2.5mg by doing 30 clicks out of the 5mg for a couple of weeks then reordered 2.5mg and have been on that since.

I average a 2 - 3lb loss a week and have lost 3 stone in all since I started in December.

I didn't have suppression the week I had off, but I kept up the healthy eating and drinking 2-3 litres of water a day, and still lost weight, the mj stays in your system for a while.

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