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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Spreading dose

1 reply

PowderPants · 24/02/2025 19:14

I'm 6 months in and 2 stone down- so losing steadily and happy with what I am achieving.
I have worked slowly up to 10mg and did this in small increments (1mg per week with a pen dose change) as I got bad side effects with larger dose jumps.
I have now been on 10mg for about 5 weeks.
My week starts with total loss of appetite for 3 days (indeed mild nausea and severe heart burn) and I have to force myself to eat as would not if I didn't. Then better for another 2 days and bloody ravenous days 5-7!
My pen ran out on Saturday and the next pen only arrived today. I took the last 5mg of my last pen on Saturday and have felt good food suppression since. I was going to take the remaining 5mg as soon as the next pen arrived.
However I am wondering if I can delay the next dose to Wednesday? That way I don't get the peak/trough effects that I am currently?
Has anyone done this?

In short can I split a once weekly 10mg dose to two 5mg doses spread over the week? Anyone know if the pharmacodynamics of that are okay?
Thanks

OP posts:
WeAllHaveWings · 24/02/2025 19:48

Even if someone on MN said the "pharmacodynamics" were ok, how on earth would you validate their qualifications to give that opinion? 🤔

Some pharmacists advise if you are coming to the end of a pen and suppression is wearing of injecting a day or two earlier as a temporary solution for 1-2 weeks before going up to the next strength. No pharmacist qualified, or responsible, will approve twice weekly injections ongoing unless Eli Lilly agreed it was ok.

So that leaves you with deciding on whether you take the risk of additional stress on your body/organs processing two injections a week. Doesn't matter if others have done it before, they are not you. It is a risk tolerance based decision.

Personally I wouldn't do that "tweak" as too many unknowns.

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