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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

3.75mg - is anyone doing this?

39 replies

Cosycover · 03/09/2024 18:35

Very reluctant to go straight from 2.5 to 5 as I have a few things on during this time and don't want to be ill.

Is anyone doing the twists for 3.75, and if so, can you explain how to do this?

Thanks!

OP posts:
Bellyblueboy · 31/10/2024 08:31

Probably six? But you have to use it in 30 days so you should really only take 5

EliLilly · 31/10/2024 08:35

You can technically get 7 doses of 3.75 mg out of a 5 mg pen, but as PP said - due to the 30 day issue with the multi-use vial it is 5 doses (on assumption of one a week). I've used doses less than 5 mg out of my last three 5 mg pens and always discard what is left after my 5th dose - just not worth the risk.

Slimmingtime · 31/10/2024 16:31

I started a thread, when you do the hard twist, can you still count clicks or is it just free wheeling and broken so you don’t know how much is coming out?

Lisany · 04/11/2024 11:32

How many doses of 3.75mg will I get out of my 5mg pen?
thanks xx

Bellyblueboy · 04/11/2024 11:49

Lisany · 04/11/2024 11:32

How many doses of 3.75mg will I get out of my 5mg pen?
thanks xx

Hi this has been discussed a few posts up

MooDeng · 04/11/2024 11:50

Lisany · 04/11/2024 11:32

How many doses of 3.75mg will I get out of my 5mg pen?
thanks xx

4 x 5mg doses = 20mg

So you'd get 5 x 3.75mg (18.75)

And you'd have a bonus dose too.

So 6 weeks but that takes you over the recommended cut of of 30days to use the pen.

HKJ84 · 03/09/2025 22:16

MooDeng · 15/10/2024 13:21

I'm doing 2.5mg twice a week rather than 5mg weekly

How do you get on doing 2.5mg twice a week? I’ve been thinking about this but wasn’t sure if it was ok to do.

gallivantsaregood · 03/09/2025 22:38

@HKJ84I tried it but it was still too much suppression. So I'm now doing 3.75mg, maybe every 7, 6 or 5 days. I'll see how I feel come day 5 and decide then.

HKJ84 · 04/09/2025 08:35

gallivantsaregood · 03/09/2025 22:38

@HKJ84I tried it but it was still too much suppression. So I'm now doing 3.75mg, maybe every 7, 6 or 5 days. I'll see how I feel come day 5 and decide then.

Thanks for replying. That sounds like a good idea. I did 5mg for 8 weeks and tried to battle through but had 3 or 4 really nasty bouts of D&V and thought- this isn’t worth it. So I was advised to go back to 2.5mg but not really getting any suppression or feel like it’s supporting me any more than if I was just in a calorie deficit off the meds. I tried 3.75 for the first time last night. Got that fuzzy hangover feeling but no sickness or other symptoms yet. We’ll see!

ShuriPouri · 04/09/2025 08:38

https://www.vrgrowth.co.uk/mounjaro-clicks

here use this online calculator to work out your clicks and if you prefer split dosing etc. It is very easy and simple to use. Watch the video if you are unsure how the calculator works, but I found it very intuitive.

Mounjaro Click Count & Dose Calculator | Fat Old Climber

Mounjaro click count & dosing calculator. Calculate injections, costs per week, savings & dose schedules. Ideal for weight loss and saving money on Mounjaro.

https://www.vrgrowth.co.uk/mounjaro-clicks

Outspoken61 · 24/02/2026 22:47

For those worried about exceeding 30 days, not true, it lasts much longer than that

Bearsdolovetrees · 24/02/2026 22:51

WeAllHaveWings · 03/09/2024 21:17

I've had 6 weeks of 3.75mg now and it is working well for me.

I inject on a Saturday afternoon, feel a bit tired Sunday evening and very low appetite Monday-Wednesday-ish. Thursday/Friday ok suppression and I can eat reduced portions but nearly normally Saturday/Sunday - but over the week I keep within my weekly calorie deficit.

The 45 clicks also mean you don't need to hard twist for the 5th dose, but it is very tempting the 6th one that's left (but it is beyond 30 days).

30 days means nothing apart from ‘we want you to buy another pen.’ It does not suddenly become dangerous. If it did there would be a lot more stringent rules. I’ve used ones over 2-3 months and always fine and working

Bearsdolovetrees · 24/02/2026 22:53

EliLilly · 31/10/2024 08:35

You can technically get 7 doses of 3.75 mg out of a 5 mg pen, but as PP said - due to the 30 day issue with the multi-use vial it is 5 doses (on assumption of one a week). I've used doses less than 5 mg out of my last three 5 mg pens and always discard what is left after my 5th dose - just not worth the risk.

What risk do you think there is? Do you think people don’t use this dose? And do you think anything has ever ever ever happened to those that do? And if it had don’t you think it would be headline news and there would be huge restrictions.

WeAllHaveWings · 24/02/2026 23:06

@Bearsdolovetrees why are you resurrecting threads and quoting posts from so long ago, things have moved on since then.

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