I've been using skin + me for the last month, and am on an incredibly low dose of tret (0.006), but I think I can see an improvement!! My skin has been feeling softer and more "elastic" somehow (although I thought that might be due to slathering in moisturiser to soothe the dryness I experienced for a couple of weeks). I feel like my face just looks a bit brighter. I took a pic before starting and another one a couple of days ago. I've put them together and I think I can see a little softening of my (intense) frown lines. I'm so pleased! Can you see it too? (first pic on the left, new pic on the right). I'm annoyed that I didn't get the lighting the same, so I look more pink in the recent photo.