Well William has the Middleton home as a safe and easy sanctuary. The Royal Family is vast but they are like satellites with their own paths. They only occasionally intersect and seem to keep themselves to themselves the rest of the time. It's not like they can just pop in unannounced anywhere.
I don't have much close family and it is bit sad. I have no parents to see at the weekend, no family home to visit. However once kids come, you tend to make your own little nucleus and you grow up a bit. A welcoming family is nice to have, but you realise that actually you will be the welcoming family for the kids when they grow up. So it's just the way life goes.
I imagine it is harder if there are no kids. I have a sister with no kids and she finds weekends lonely. So she tends to drop in on us! So I guess we have become the substitute for that family nest.
It's easier to have a cosy loving Middleton background, but you can be content without it, is my point.