Cystic fibrosis carriers

[farfromperfect82]

Hi there. I wonder if anyone can help me with this? I just found out that both me and my partner are carriers of the Cystic Fibrosis gene. We were due to start IVF in February.

I believe that there is some testing that can be done on embryos to check them before? Has anyone got any experience of this

I know it's expensive and I know my chosen clinic doesn't do it so will mean changing clinics I think 😥

Hi, no direct experience, no, but basically the embryos are sampled then frozen until results come back. Basically to have CF you need to inherit a "dodgy" copy of the gene from both parents. Statistically there's a 1 in 4 chance that each embryo would receive the "dodgy" copy from both parents and be affected, so 25% chance any developing baby would have CF, 75% chance the embryo would be fine.

Are you in the UK? I'm assuming you're going private but it'd be worth asking your GP if they can refer you to your local genetics clinic to see if they can help. At the very least they should be able to offer you counselling to fully discuss the implications.

Hope things go well x

Hi @farfromperfect82

We are waiting to have PGD- Pre-implantation genetic diagnosis IVF at Guys hospital in London due to my husband have a balanced reciprocal translocated gene formation, basically the chromosomes he sends over to me to create a baby are unbalanced resulting in multiple miscarriages and possible disabilities and birth defects should I go full term.

I had so many tests done to find out what was happening and it was the last blood test from my husband that showed this condition so we were then referred for PGD and IVF NHS funding.

I would speak to your GP ASAP because you may be entitled to PGD so they can test the embryos and pick the ones with out the CF genes so long as neither of you have any children already?